Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

dodemorph acetate (Ref: BAS 238F)
** cyclomorph ** meltatox ** milban ** 22341 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for dodemorph acetate

Description: A systemic morpholine fungicide for powdery mildew and other disease control

Example pests controlled: Powdery mildew; Rusts; Leaf spot

Example applications: Ornamentals including potted flowering shrubs (e.g. roses) and field grown plants - not cut flowers

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1968

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Netherlands/Italy
Date inclusion expires 31/08/2022
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C20H39NO3
Canonical SMILES CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) YLJLLELGHSWIDU-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide
Substance group Morpholine
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Systemic with protective and curative action. Inhibits sterol biosynthesis in membranes.
CAS RN 31717-87-0
EC number 250-778-2
CIPAC number 300
US EPA chemical code 110401
PubChem CID 61898
Molecular mass (g mol-1) 341.53
PIN (Preferred Identification Name) acetic acidó4-cyclododecyl-2,6-dimethylmorpholine (1/1)
IUPAC name 4-cyclododecyl-2,6-dimethylmorpholine acetate
CAS name 4-cyclododecyl-2,6-dimethylmorpholine acetate
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 5
Examples of recorded resistance -
Physical state Colourless solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • BASF
Example products using this active
  • Meltatox
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details -


ENVIRONMENTAL FATE

for dodemorph acetate

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 746 A5 High
Solubility - In organic solvents at 20oC (mg l-1) 1000000 A5 - Chloroform -
846000 L3 - Cyclohexane -
1000000 A5 - Ethyl acetate -
66000 L3 - Ethanol -
Melting point (oC) 42 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 158 A5 -
Flashpoint (oC) 73.8 A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.70 X 1004 Calculated -
Log P 4.23 L3 High
Bulk density (g ml-1)/Specific gravity 0.93 L3 -
Dissociation constant (pKa) at 25oC 8.5 A5 -
Note: Weak acid
Vapour pressure at 20oC (mPa) 12 L3 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 0.008 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.62 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 206nm = 1008, no absorbance 400-750nm A5 -
Surface tension (mN m-1) 55.1 A5 at 20oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 41 A3 Moderately persistent
DT50 (lab at 20oC) 36 A3 Moderately persistent
DT50 (field) - - -
DT90 (lab at 20oC) 118 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range Dodemorph 24-83 days, DT90 range 79-274 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 3.6 A5 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 45 A5 Moderately persistent
Note Not pH sensitive
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 214 A5 Non-mobile
Kfoc 25200
1/n 0.855
Notes and range EU dossier kf range 54-336, kfoc range 5300-49000 mL/g, 1/n range 0.7416-0.9452
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
dodemorph This metabolite may cause environmental pollution, click here for further information Soil   1.00   Major fraction; Relevant


ECOTOXICOLOGY

for dodemorph acetate

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) - - -
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 4100 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) - - -
Birds - Short term dietary (LC50/LD50) > 280 mg kg feed-1 A4 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 1.23 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 100 A5 Oncorhynchus mykiss Low
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 1.48 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 80 A5 Daphnia magna Low
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 1.1 L3 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) 250 A4 Unknown species Low
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 76.6 A5, as dodemorph Moderate
Oral acute 48 hour LD50 (μg bee-1) > 106.3 A5, as dodemorph Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 824 A5 as dodemorph Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 204.8 48 hour, as dodemorph
A5 Aphidius rhopalosiphi, adult
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 291 7 day, as dodemorph
A5 Typhlodromus pyri
-
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect [Dose: 50 mg kg-1 soil, 28 days]
Carbon mineralisation: No significant adverse effect [Dose: 3.13 mg kg-1 soil, 28 days]
A5 -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for dodemorph acetate

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 4100 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.0 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.1 A2 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.4 A2 Rabbit, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.04 A2 Dog, SF=100 -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Negligible risk to bystanders
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; Calc MAC=2.5 μg l-1; A5 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues No further information available

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Corrosive
Not explosive or oxidising
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H315, H319, H335
Environment: H411
EC Risk Classification Click here to view information omn the EU risk phrases N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S60, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Usually 2588
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for dodemorph acetate

Language Name
English dodemorph acetate
French acetate de dodemorfe
German Dodemorphacetat
Danish -
Italian -
Spanish acetato de dodemorf
Greek -
Slovenian dodemorf acetat
Polish octan dodemorfu
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 30 May 2018
Contact: aeru@herts.ac.uk