Monocrotophos (Ref: ENT 27129)
Last updated: 19/01/2023
(Also known as: azadrin; corophos; OMS 834)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Used to control sucking and chewing pests typically on cotton, citrus and many other crops
Aphids; Common mites; Ticks; Spiders; Caterpillars
Cotton; Palms; Ornamental conifers; Ornamental shrubs and flowers; Peanuts; Sugarcane; Citrus; Olives
-
Banned in many countries
-
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Italy
Expired
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
Exists in the cis- and trans-forms.The cis-form is the major constituent of the technical material.
C₇H₁₄NO₅P
C/C(=C\C(=O)NC)/OP(=O)(OC)OC
C/C(=C\C(=O)NC)/OP(=O)(OC)OC
KRTSDMXIXPKRQR-AATRIKPKSA-N
InChI=1S/C7H14NO5P/c1-6(5-7(9)8-2)13-14(10,11-3)12-4/h5H,1-4H3,(H,8,9)/b6-5+
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
monocrotophos
-
Insecticide, Acaricide
Organophosphate insecticide; Organophosphate acaricide
-
-
Synthetic
Broad spectrum, systemic with stomach and contact action. Acetylcholinesterase (AChE) inhibitor.
6923-22-4
230-042-7
287
058903
5371562
015-072-00-9
223.16
dimethyl (2E)-4-(methylamino)-4-oxobut-2-en-2-yl phosphate
dimethyl (E)-1-methyl-2-(methylcarbamoyl)vinyl phosphate
dimethyl (1E)-1-methyl-3-(methylamino)-3-oxo-1-propenyl phosphate
PIC Annex III; Marine Pollutant; Rotterdam Convention (Class Ib)
-
Not applicable
Not applicable
1B
Not applicable
Bemisia tabaci , Boophilus microplus , Cacopsylla pyri , Earias vittella , Lygus hesperus , Spodoptera littoralis , many others
Colourless crystals when pure reddish-brown as technical substance
BASF AgroCare King Tech Corp United Phosphorus
Nuvacron Crisodrin Monophos Monodrin Phoskill
Available as a water soluble concentrate and ULV formulation
818000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
High
700000
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Acetone
-
1000000
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Methanol
-
10000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Toluene
-
292000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Ethanol
-
54
-
-
-
-
-
-
-
-
-
-
6.03 X 10-01
Calculated
-
-0.22
Low
-
-
-
-
-
-
1.16
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
-
-
-
-
-
0.29
Low volatility
-
-
-
-
-
-
-
-
-
-
7
Non-persistent
-
-
-
30
Moderately persistent
-
-
-
-
-
-
-
-
-
Literature values for soil DT₅₀ range 1-35 days
5.0
R4 R = Peer reviewed scientific publications 4 = Verified data
-
Published literature RL₅₀ range 2.4-7.8 days, 2 field grown crops, various matrices, n=2
3.7
R4 R = Peer reviewed scientific publications 4 = Verified data
-
Published literature RL₅₀ range 1.3-14.5 days, 10 field grown crops, various matrices, n=11
26
P3 P = Other governments and regulators 3 = Unverified data of known source
Slow
-
134
P3 P = Other governments and regulators 3 = Unverified data of known source
Persistent
-
-
-
-
-
-
-
Soil adsorption and mobility
-
P3 P = Other governments and regulators 3 = Unverified data of known source
Mobile
19
Literature values for Koc range 0.9-30.8 mL g⁻¹
-
-
-
-
-
-
-
4.02
Calculated
High leachability
8.78 X 10-01
Calculated
-
-
Low
Calculated
-
Mobile
Calculated
-
Low risk
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Based on LogP < 3
Low risk
-
-
None
Terrestrial ecotoxicology
14
Rat
High
-
-
-
-
-
-
-
-
> 0.94
Colinus virginianus
High
-
-
-
-
-
-
35
R4 R = Peer reviewed scientific publications 4 = Verified data
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.13
K3 K = Research datasets, e.g. Pandora, Demetra 3 = Unverified data of known source
Apis mellifera
High
0.02
R4 R = Peer reviewed scientific publications 4 = Verified data
Apis mellifera
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1.1
R4 R = Peer reviewed scientific publications 4 = Verified data
Megachile rotundata
Moderate
Contact
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 7.0
Oncorhynchus mykiss
Moderate
-
-
-
0.023
Daphnia magna
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
14
Rat
High
157
Rat
-
-
-
-
-
-
-
0.0006
JMPR 1995
-
0.002
JMPR 1995
-
-
-
-
-
-
-
-
-
-
List I; List II
-
-
Minimal risk from food residues Exposure by general public unlikely
Full protective clothing required including respirator to minimise operator and worker exposure May be absorbed through skin
EU MRL pesticide database 
-
-
-
-
-
-
-
In mammals, 60-65% is excreted within 24 hours, predominantly in the urine
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E1 E = Unspecified genotoxicity type (miscellaneous data source) 1 = Positive
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
✓Yes, known to cause a problem
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Highly toxic orally
Corrosive IMDG Transport Code is 6.1
Health: H300, H311; H330; H340 Environment: H400, H410
Ib (Highly hazardous)
2783
-
monocrotophos
monocrotophos
Monocrotophos
-
-
monocrotofos
-
monokrotofos
-
-
-
Record last updated:
19/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242