Benzofenap (Ref: MY 71)
Last updated: 19/08/2023
(Also known as: Yukawide)
Benzofenap is a herbicide used mainly to control broad-leaved weeds in water-seeded rice. It has a low aqueous solubility, is not volatile and is moderately persistent in soil systems with a low risk of leaching to groundwater. Benzofenap tends to have a low to moderate toxicity to biodiversity. Its toxicity to mammals including humans is low if ingested. It is also a skin irritant.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Used mainly to control broad-leaved weeds in water-seeded rice
Seedings of water plantain (Sagittaria montevidensis ), Maddog weed (Alisma plantago aquatica ), Lance-leaf water plantain (Alisma lanceolatum ), Starfruit plantain (Damasonium minus ), Flatsedge (Cyperus difformis )
Paddy rice
-
Current
1981, first synthesized; 1987, first registered Japan
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₂₂H₂₀Cl₂N₂O₃
CC1=CC=C(C=C1)C(=O)COC2=C(C(=NN2C)C)C(=O)C3=C(C(=C(C=C3)Cl)C)Cl
No data
JDWQITFHZOBBFE-UHFFFAOYSA-N
InChI=1S/C22H20Cl2N2O3/c1-12-5-7-15(8-6-12)18(27)11-29-22-19(14(3)25-26(22)4)21(28)16-9-10-17(23)13(2)20(16)24/h5-10H,11H2,1-4H3
Yes
Herbicide
Benzoylpyrazole herbicide
-
-
Synthetic
Systemic, absorbed through roots. Bleaching inhibition of 4-hydroxyphenyl-pyruvate-dioxygenase.
82692-44-2
No data found
None allocated
Not listed
94686
No data found
431.31
2-{[4-(2,4-dichloro-3-methylbenzoyl)-1,3-dimethyl-1H-pyrazol-5-yl]oxy}-1-(4-methylphenyl)ethan-1-one
2-[4-(2,4-dichloro-m-toluoyl)-1,3-dimethylpyrazol-5-yloxy]-4'-methylacetophenone
2-[[4-(2,4-dichloro-3-methylbenzoyl)-1,3-dimethyl-1H-pyrazol-5-yl]oxy]-1-(4-methylphenyl)ethanone
-
-
F2
27
Not applicable
Not applicable
-
White solid
Bayer CropScience Rhone poulenc
Usually supplied as a flowable concentrate or as granules
0.13
at 25 °C
Low
69000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Xylene
-
73000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
5600
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
n-Hexane
-
920000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Chloroform
-
133.3
-
-
-
-
-
-
-
-
-
-
4.90 X 1004
Calculated
-
4.69
High
-
-
-
-
-
-
1.09
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
-
-
-
0.013
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
-
-
-
-
-
-
-
-
-
-
38
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Data for paddy fields
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
Non-mobile
6405
Estimated
-
-
-
-
-
-
-
0.31
Calculated
Low leachability
7.73 X 10-03
Calculated
-
-
Medium
Calculated
-
Non-mobile
Calculated
-
-
-
-
-
-
None
Terrestrial ecotoxicology
> 15000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Low
-
-
-
-
-
-
-
-
> 2000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Coturnix japonica
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 0.762
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 0.383
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.148
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Pseudokirchneriella subcapitata
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 15000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Low
5000
Rat
-
1.93
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
No further information available
No information available
Health: H332 Environment: H400, H410
Not listed (Not listed)
-
-
-
benzofenap
-
-
-
-
-
-
benzofenap
-
-
-
-
Record last updated:
19/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242