Fentrazamide (Ref: BAY YRC 2388)
Last updated: 19/08/2023
(Also known as: YRC 2388; NBA 061)
Fentrazamide is a tetrazolinone herbicide for use in rice. It has a very low aqueous solubility, is relatively volatile and very persistent in water systems but much less so in soil. It has a low mammalian toxicity, however there is little reported information on human health effects. It is moderately toxic to birds, most aquatic organisms and earthworms but is not toxic to honeybees.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A post-emergence herbicide for rice crops
Barnyard grass, Annual sedges, Broadleaved weeds
Rice
-
Current
circa 1997
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₁₆H₂₀ClN₅O₂
CCN(C1CCCCC1)C(=O)N2C(=O)N(N=N2)C3=CC=CC=C3Cl
-
LLQPHQFNMLZJMP-UHFFFAOYSA-N
InChI=1S/C16H20ClN5O2/c1-2-20(12-8-4-3-5-9-12)15(23)22-16(24)21(18-19-22)14-11-7-6-10-13(14)17/h6-7,10-12H,2-5,8-9H2,1H3
Yes
Herbicide
Tetrazolinone
-
-
Synthetic
Selective, inhibits very long chain fatty acid synthesis and so cell division (Inhibition of VLCFAs)
158237-07-1
605-140-1
None allocated
-
3081363
No data found
349.82
4-(2-chlorophenyl)-N-cyclohexyl-N-ethyl-5-oxo-4,5-dihydro-1H-tetrazole-1-carboxamide
4-(2-chlorophenyl)-N-cyclohexyl-N-ethyl-4,5-dihydro-5-oxo-1H-tetrazole-1-carboxamide
4-(2-chlorophenyl)-N-cyclohexyl-N-ethyl-4,5-dihydro-5-oxo-1H-tetrazole-1-carboxamide
-
-
K3
15
Not applicable
Not applicable
-
Colourless crystalline solid
2.3
at 25 °C
Low
2100
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
n-Heptane
-
32000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Isopropanol
-
250000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Xylene
-
250000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Dichloromethane
-
79
-
-
-
-
-
-
-
-
-
-
3.98 X 1003
Calculated
-
3.60
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
-
-
-
-
-
-
1.30
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
0.05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
7.0 X 10-06
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
30
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Literature values state DT₅₀ in paddy field conditions is around 30 days in volcanic soil and 20 days in alluvial soil.
-
-
-
-
-
-
-
-
20
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Slow
DT₅₀ 20 days in pure water, 10 days in natural waters
Stable
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Stable
Stable pH 5 to pH 9
-
-
-
-
-
-
Soil adsorption and mobility
-
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Moderately mobile
100
Literature values range from 300 to 3400
-
-
-
-
-
-
-
2.95
Calculated
High leachability
2.49 X 10-01
Calculated
-
-
Low
Calculated
-
Moderately mobile
Calculated
-
-
-
-
-
-
None
Terrestrial ecotoxicology
> 5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
10.3
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
High
-
-
-
-
-
> 2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Coturnix japonica
Low
-
-
-
-
-
-
> 1000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 150
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3.4
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 10.0
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.006
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Green algae
High
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
> 5.0
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No data found
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
No further information available
IMDG Transport Hazard Class 9 Not expected to autoignite; Not highly flammable
Environment: H400
Not listed (Not listed)
UN3077
Packaging Group III (minor danger)
-
fentrazamide
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-
-
-
-
-
fentrazamid
-
-
-
-
Record last updated:
19/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242