Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

EPN (Ref: OMS 219)
** ENT 17298 ** HSDB 4049 ** tsumaphos ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for EPN

Description: Used to control Lepidoptera larva, especially bollworms in a range of crops including cotton

Example pests controlled: Bollworms; Rice stem borer; Oriental fruit moth; Armyworms; Leaf miners; Mexican bean beetles; Leafrollers; Tobacco budworm; Boll weevils

Example applications: Cotton; Rice; Fruit; Vegetables; Tobacco

Efficacy & activity: -

Availability status: Unknown

Introduction & key dates: -

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires Not applicable
EU Candidate for substitution (CfS) Not applicable
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism EPN is a chiral molecule having a have a (+)- and a (-)-isomer. Commercial products are isomeric mixtures with the (+)-form showing the greatest insecticidal activity and also the least neurotoxicity.
Chemical formula C14H14NO4PS
Canonical SMILES CCOP(=S)(C1=CC=CC=C1)OC2=CC=C(C=C2)[N+](=O)[O-]
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) AIGRXSNSLVJMEA-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C10H13NO2/c1-7-4-8(2)6-9(5-7)13-10(12)11-3/h4-6H,1-3H3,(H,11,12)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide
Substance group Organophosphate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Non-systemic with contact and stomach action, works by cholinesterase inhibition
CAS RN 2104-64-5
EC number 218-276-8
CIPAC number 302
US EPA chemical code 041801
PubChem CID 16421
Molecular mass (g mol-1) 323.30
PIN (Preferred Identification Name) (E)-[O-ethyl O-(4-nitrophenyl) phenylphosphonothioate]
IUPAC name (RS)-(O-ethyl O-4-nitrophenyl phenylphosphonothioate)
CAS name O-ethyl O-(4-nitrophenyl) phenylphosphonothioate
Other status information Severe Marine Pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Chilo suppressalis
Plutella xylostella
Psylla pyricola
Tetranychus bimaculatus
Physical state Yellow crystals
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically -
Example products using this active -
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details -


ENVIRONMENTAL FATE

for EPN

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.5 F3 Low
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting point (oC) 34.5 L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 1.05 X 1005 Calculated -
Log P 5.02 L3 High
Bulk density (g ml-1)/Specific gravity 1.27 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 0.041 L3 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) - - -
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.47 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 8.95 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 15 F3 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) 15 F3 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note USDA data; Other data sources quote DT50 <15 days in paddy fields
Dissipation rate RL50 on plant matrix Value 4.0 R4 -
Note Published literature RL50 range 1.0-7.0 days, cotton leaves, n=2
Dissipation rate RL50 on and in plant matrix Value 5.6 R4 -
Note Published literature RL50 range 3.0-10.0 days, fruit & leaves of 2 orchard crops, n=4
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - US3 Non-mobile
Koc 4000
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for EPN

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 2346 R3 Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 14 F3 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 289 F3 Colinus virginianus Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.110 F3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.00006 F3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.003 F3 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) 0.237 Q3 High
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for EPN

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 14 F3 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 538 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.106 V3 Rat, 1 hr -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits [LT TWA (USA) 8-hr: 0.5 mg/m3], [STEL: 2 mg/l] F3 -
Exposure Routes Public -
Occupational May be absorbed through the skin
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

-

-

General human health issues Inhalation and ingestion may cause a variety of symptons including convulsions, dizziness, sweating, breathing difficulties, nausea and unconsciousness

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes IMDG Transport Code is 6.1
CLP classification 2013 Health: H300, H310
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Highly toxic: R27/28
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S22, S36/37, S45, S60, S61
WHO Classification Ia - Extremely hazardous
US EPA Classification (formulation) I - Danger - Highly toxic
UN Number 2783
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for EPN

Language Name
English EPN
French EPN
German EPN
Danish EPN
Italian EPN
Spanish EPN
Greek EPN
Slovenian EPN
Polish EPN
Swedish EPN
Hungarian EPN
Dutch EPN

Record last updated: Friday 25 May 2018
Contact: aeru@herts.ac.uk