Cycloprothrin is a pyrethroid insecticide. It has a low aqueous solubility and is non-volatile. It may be persistent in soil and water systems depending upon local conditions. It is not expected to leach to groundwater. Cycloprothrin tends to have a low to moderate toxicity to biodiversity depending on species. It has a low oral mammalian toxicity.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate High alert: Potential for particle bound transport: High
Human health Moderate alert: Possible Endocrine distrupter
Warning: Significant data are missing
GENERAL INFORMATION
Description
Used to control rice water weevils and other insects in paddy fields and on other crops
Example pests controlled
Rice water weevils; Vine weevils; Leaf miners
Example applications
Paddy rice; Fruit and vines; Vegetables; Forestry; Cotton
Efficacy & activity
-
Availability status
-
Introduction & key dates
1987, Japan
UK regulatory status
UK COPR regulatory status
Not approved
Date COPR inclusion expires
Not applicable
UK LERAP status
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
EC Regulation 1107/2009 status
Not approved
Dossier rapporteur/co-rapporteur
Not applicable
Date EC 1107/2009 inclusion expires
Not applicable
EU Candidate for substitution (CfS)
Not applicable
Listed in EU database
No
Approved for use (✓) under EC 1107/2009 in the following EU Member States
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
Approved for use (✓) under EC 1107/2009 by Mutual Recognition of Authorisation and/or national regulations in the following EEA countries
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
Additional information
Also used in
-
Chemical structure
Isomerism
Cycloprothrin is a molecule with 2 chiral centres. The commerical product is an isomeric mixture of the 4 stereoisomers. The (1R, alphaR)-isomer demonstrates the greatest insecticidal activity being roughly 5x stronger than the racemic mixture.
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242