Diclomezine (Ref: F-850)
Last updated: 03/09/2023
(Also known as: SF-7531)
Diclomezine is a curative and protective fungicide. It has a low aqueous solubility and is volatile. There are significant gaps in reported fate data. It is highly toxic to mammals. Diclomezine moderately toxic to honeybees but is relatively non-toxic to most aquatic organisms and birds.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An unclassified fungicide used to control various pathogens in rice and other crops
Twig rot; Rice sheath blight; White mildew
Rice; Peanuts; Turf; cereals; Oilseeds
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1988, first introduced Japan
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₁₁H₈Cl₂N₂O
CC1=C(C=C(C=C1Cl)C2=NNC(=O)C=C2)Cl
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UWQMKVBQKFHLCE-UHFFFAOYSA-N
InChI=1S/C11H8Cl2N2O/c1-6-8(12)4-7(5-9(6)13)10-2-3-11(16)15-14-10/h2-5H,1H3,(H,15,16)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
diclomezine
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Fungicide
Pyridazine fungicide
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Synthetic
Curative and protectant activity, works by inhibiting the formation of septum and mycelial growth.
62865-36-5
No data found
None allocated
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93341
No data found
255.1
6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2H)-one
6-(3,5-dichlorophenyl-p-tolyl)pyridazin-3(2H)-one
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Not applicable
Not applicable
Not applicable
37
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Colourless crystalline solid
Supplied in a variety of formulations including soluble concentrates and wettable powders
0.74
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
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3400
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
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252
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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4.47 X 1002
Calculated
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2.65
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
Low
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1.44
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
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0.013
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
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Soil adsorption and mobility
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Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
Slightly mobile
654
Estimated
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Cannot be calculated
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Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
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None
Terrestrial ecotoxicology
> 12000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
98.9
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
High
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> 7000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Colinus virginianus
Low
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> 100
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Apis mellifera
Low
> 100
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Apis mellifera
Low
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> 300
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Cyprinus carpio
Low
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> 300
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Low
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 12000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
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0.82
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
Toxic if inhaled
No information available
Health: H331
U (Unlikely to present an acute hazard)
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diclomezine
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dichlomezyna
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Record last updated:
03/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242