Bromobutide (Ref: S 4347 )
Last updated: 03/09/2023
(Also known as: S-47)
Bromobutide is a post-emergence herbicide mainly used in Japan, It has a low aqueous solubility and is a moderately volatile substance. It may be prone to drift. Little information is available regarding its environmental fate. It is moderately toxic to fish. It has a low mammalian toxicity via the human route but other human health information is scant.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A selective, post emeregnce herbicide that is currently used to control perennial weeds in paddy fields
Cockspur (Echinochloa oryzicola ); False pickerelweed (Monochoria vaginals ); Rotala indica ; Scirpus juncoides
Paddy rice
-
Current
1981, first reported
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
A chiral molecule. Substance is racemic.
C₁₅H₂₂BrNO
CC(C)(C)C(C(=O)NC(C)(C)C1=CC=CC=C1)Br
-
WZDDLAZXUYIVMU-UHFFFAOYSA-N
InChI=1S/C15H22BrNO/c1-14(2,3)12(16)13(18)17-15(4,5)11-9-7-6-8-10-11/h6-10,12H,1-5H3,(H,17,18)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
bromobutide
-
Herbicide
Amide herbicide
-
-
Synthetic
Inhibition of 4-hydroxyphenyl-pyruvate dioxygenase, bleaching
74712-19-9
No data found
None allocated
Not listed
53079
No data found
312.25
rac-(2R)-2-bromo-3,3-dimethyl-N-(2-phenylpropan-2-yl)butanamide
(RS)-2-bromo-3,3-dimethyl-N-(1-methyl-1-phenylethyl)butyramide
2-bromo-3,3-dimethyl-N-(1-methyl-1-phenylethyl)butanamide
May be prone to drift.
-
Z
0
Not applicable
Not applicable
-
Colourless to yellow crystals
3.54
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
at 25 °C
Low
4700
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Xylene
-
35000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Methanol
-
500
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Hexane
-
-112
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
101.4
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
-
-
23
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
(closed cup)
-
3.02 X 1003
Calculated
-
3.48
High
-
-
-
-
-
-
1.276
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
-
-
-
74.0
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Highly volatile
6.53
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Moderately volatile
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
-
-
-
-
-
None
Terrestrial ecotoxicology
> 5000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 10.0
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Cyprinus carpio
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 5000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Low
5000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May cause damage to lungs and mucous membranes
Flammable
-
U (Unlikely to present an acute hazard)
UN1126
Packaging Group II (moderate danger)
-
bromobutide
-
-
-
-
-
-
-
-
-
-
-
Record last updated:
03/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242