1,2-dibromoethane is a largely obsolete insecticide. It is not approved for use in many countries. It is highly soluble in water and volatile, classified as a POP. It can be very persistent in soil systems depending on soil type and environmental conditions. It also has the potential to leach to groundwater. 1,2-bromoethane tends to have a low to medium toxicity to most biodiversity although there are gaps in data. It has a moderate level of oral toxicity to humans, is a probable carcinogen and may also affect human fertility/reproduction.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate High alert: Very persistent; GUS: High leachability
Ecotoxicity Moderate alert: Birds acute ecotoxicity: Moderate; Fish acute ecotoxicity: Moderate; Fish chronic ecotoxicity: Moderate
Human health High alert: Carcinogen; Reproduction/development effects
GENERAL INFORMATION
Description
A largely obsolete post-harvest pesticide, often used in mixtures, to control termites and other insect pests
Example pests controlled
Termites; Ants; Japanese and other beetles; Moths; Nematodes; Wireworms
Example applications
Fruit including citrus, tropical fruit; Vegetables; Cereals
Efficacy & activity
-
Availability status
Considered obsolete but may be available in some countries; Banned in many countries
Introduction & key dates
-
UK regulatory status
UK COPR regulatory status
Not approved
Date COPR inclusion expires
Expired, banned
UK LERAP status
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
EC Regulation 1107/2009 status
Not approved
Dossier rapporteur/co-rapporteur
Not applicable
Date EC 1107/2009 inclusion expires
Expired, banned 2010
EU Candidate for substitution (CfS)
Not applicable
Listed in EU database
Yes
Approved for use (✓) under EC 1107/2009 in the following EU Member States
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
Approved for use (✓) under EC 1107/2009 by Mutual Recognition of Authorisation and/or national regulations in the following EEA countries
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Octanol-water partition coefficient at pH 7, 20 °C
P
9.12 X 1001
Calculated
-
Log P
1.96
V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source
Low
Fat solubility of residues
Solubility
Soluble
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
-
Data type
Regulatory data - observed in metabolism and farm animal feeding studies
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes
Risk of exposure from agricultural sources is negligible Possible risk in some countries via consumption of contaminated drinking water
Occupational
May be absorped through inhalation, ingestion, or the skin
MRLs
European
EU MRL pesticide database
Great Britain
GB MRL Register
Notes
-
Drinking Water Standards
Non-statutory WHO drinking water guideline 0.0004 mg l⁻¹
B5 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) 5 = Verified data used for regulatory purposes
UK EA QS database 2018
-
Drinking Water MAC (μg l⁻¹)
-
-
-
Mammalian dose elimination route and rate
-
-
-
Health issues
Specific human health issues
Carcinogen
Genotoxic
Endocrine disruptor
✓Yes, known to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
;
B0 B = DNA damage/repair (EFSA database) 0 = No data
;
C0 C = Gene mutation (EFSA database) 0 = No data
;
D0 D = Genome mutation (EFSA database) 0 = No data
;
E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
?Possibly, status not identified
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
?Possibly, status not identified
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
✓Yes, known to cause a problem
No data found
General human health issues
Possible liver and kidney toxicant May cause testicular damage and antispermatogenic effects High doses may lead to death CLP data - known human carcinogen; US NTP - suspected carcinogen; OSHA - anticipated human carcinogen; US EPA - probable human carcinogen
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242
Environmental fate
Ecotoxicity
