(Also known as: TCMTB; TCMB; alentisan; KVK 733059)
SUMMARY
2-(thiocyanomethylthio)benzothiazole is a soil and seed treatment used to control various fungal and bacterial infections. It is moderately soluble in water, has a low volatility and is not expected to be persistent in soil systems. It is not expected to leach to groundwater. It has a pungent odour, is highly toxic to most aquatic species and moderately toxic to birds. 2-(thiocyanomethylthio)benzothiazole is highly toxic to humans via the oral route and is a recognised irritant.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate Moderate alert: Potential for particle bound transport: Medium
Warning: Significant data are missing
Ecotoxicity High alert: Fish acute ecotoxicity: High; Fish chronic ecotoxicity: High; Daphnia acute ecotoxicity: High; Daphnia chronic ecotoxicity: High
Human health Moderate alert: Mammals acute toxicity: Moderate; Possible Carcinogen
GENERAL INFORMATION
Description
Used as a soil and seed treatment against various diseases. Also used as a marine biocide, and as a wood and leather preservative.
Complex - reacts with the nucleophilic cell entities which causes the antimicrobial activity. Also known to inhibit flavoenzymes in the tricarboxylic acid cycle.
CAS RN
21564-17-0
EC number
244-445-0
CIPAC number
None allocated
US EPA chemical code
035603
PubChem CID
30692
CLP index number
613-119-00-3
Molecular mass
238.36
PIN (Preferred Identification Name)
-
IUPAC name
2-(thiocyanatomethylthio)-1,3-benzothiazole
CAS name
(2-benzothiazolylthio)methyl thiocyanate
Other status information
-
Relevant Environmental Water Quality Standards
-
Herbicide Resistance Class (HRAC MoA class)
Not applicable
Herbicide Resistance Class (WSSA MoA class)
Not applicable
Insecticide Resistance Class (IRAC MoA class)
Not applicable
Fungicide Resistance Class (FRAC MOA class)
Not known
Examples of recorded resistance
-
Physical state
Dark orange liquid
Formulations
Property
Value
Example manufacturers & suppliers of products using this active now or historically
-
Example products using this active
Busan 30
Busan 44
Superdavloxan
Busan 72
Formulation and application details
Usually supplied as an emulsifiable liquid, ready-to-use liquids and wettable powders
ENVIRONMENTAL FATE
Property
Value
Source; quality score; and other information
Interpretation
Solubility - In water at 20 °C (mg l⁻¹)
125
V4 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 4 = Verified data
at 24 °C
Moderate
Solubility - In organic solvents at 20 °C (mg l⁻¹)
Miscible
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Ethanol
-
Miscible
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Ethyl acetate
-
Melting point (°C)
-
-
-
Boiling point (°C)
191
F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source
-
Degradation point (°C)
60
-
-
Flashpoint (°C)
189
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
-
Octanol-water partition coefficient at pH 7, 20 °C
P
2.00 X 1003
Calculated
-
Log P
3.3
V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source
High
Fat solubility of residues
Solubility
-
-
-
Data type
-
-
-
Density (g ml⁻¹)
1.4
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
-
Dissociation constant pKa) at 25 °C
-
-
-
-
Vapour pressure at 20 °C (mPa)
-
-
-
Henry's law constant at 25 °C (Pa m³ mol⁻¹)
6.58 X 10-07
V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source
V4 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 4 = Verified data
Rat
Moderate
Mammals - Dermal LD₅₀ (mg kg⁻¹ body weight)
10000
F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source
Rabbit
-
Mammals - Inhalation LC₅₀ (mg l⁻¹)
0.0671
P3 P = Other non-EU, UK or US Governments and Regulators 3 = Unverified data of known source
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242