Chloroxylenol
Last updated: 22/01/2023
(Also known as: 2-chloro-m-xylenol; p-chloro-m-xylenol )
Chloroxylenol is a bactericide and antiseptic used mainly in public health situations. Available data is limited. It is moderately toxic to aquatic species. Mammalian toxicity is low and, whilst it may be an eye irritant, no data is available that suggests it may cause more serious health impacts unless dosages are high.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A chlorinated phenolic substance used as a biocide and sanitizer
Bacteria; Algae; Fungi
Adhesives, emulsions, paints and wash tanks; Hospitables and wound cleaning preparations; Households
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Current
1959, USA
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₈H₉ClO
CC1=CC(=CC(=C1Cl)C)O
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OSDLLIBGSJNGJE-UHFFFAOYSA-N
InChI=1S/C8H9ClO/c1-5-3-7(10)4-6(2)8(5)9/h3-4,10H,1-2H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
chloroxylenol
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Fungicide, Bactericide, Microbiocide, Veterinary substance
Chlorinated phenol compound; Unclassified pesticide
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Synthetic
Causes disruption of cell membrane potentials, blocking production of adenosine triphosphate
88-04-0
201-793-8
None allocated
086801
2723
604-038-00-4
156.61
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4-chloro-3,5-dimethylphenol
chloroxylenol
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-
Not applicable
Not applicable
Not applicable
BM01
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Colourless oily liquid with pleasant aromatic odour
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Dettol Bar-Fungal Plus Buckeye E.D.C. Environmental Disinfectant Cleaner Chase's Mildew Stops Mold And Mildew
Formulated as ready-to-use liquids, creams and as liquid concentrates
250
Moderate
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-
-
115
-
246
-
-
-
-
-
-
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1.86 X 1003
Calculated
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3.27
High
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-
-
-
-
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1.12
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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9.7
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
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-
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-
-
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-
-
-
-
-
-
-
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-
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-
-
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Soil adsorption and mobility
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Cannot be calculated
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-
-
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-
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None
Terrestrial ecotoxicology
3830
Rat
Low
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-
-
-
-
-
-
-
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-
-
-
-
-
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-
-
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-
-
-
-
-
-
-
-
-
-
-
1.6
Lepomis macrochirus
Moderate
-
-
-
6.7
Daphnia magna
Moderate
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
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-
HUMAN HEALTH AND PROTECTION
High (class III)
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-
3830
Rat
Low
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-
-
-
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Intraperitoneal LD₅₀ = 115000 mg kg⁻¹
Mouse
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-
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EU MRL pesticide database 
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Excreted in the urine as a glucuronide conjugate and as the sulfate together with some unchanged chemical
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
?Possibly, status not identified
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
IARC Carcinogen: 2B May cause nausea, vomiting, and diarrhoea May cause pulmonary edema and neurological changes Possible liver and renal toxicant
Highly corrosive
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Not listed
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chloroxylenol
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cloroxilenol
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Record last updated:
22/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242