2,2-dibromo-3-nitrilopropionamide (Ref: XD 1603)
Last updated: 05/06/2023
(Also known as: DBNPA)
2,2-dibromo-3-nitrilopropionamide is a broad specturum non-food biocide. It is highly soluble in water and in some organic solvents such as acetone and ethanol. There is little information published on its environmental fate. It is moderately toxic to aquatic organisms. 2,2-dibromo-3-nitrilopropionamide has a moderate human oral toxicity, may be a reproduction/developmental toxin nd is a recognised irritant.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
Mainly used as a non-food biocide within the paper industry and as preservatives for coatings and slurries.
Algae; Bacteria; Yeasts; Fungi
Water treatment systems; Industrial water cooling systems
-
-
1972, USA
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₃H₂Br₂N₂O
C(#N)C(C(=O)N)(Br)Br
-
UUIVKBHZENILKB-UHFFFAOYSA-N
InChI=1S/C3H2Br2N2O/c4-3(5,1-6)2(7)8/h(H2,7,8)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
2,2-dibromo-3-nitrilopropionamide
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Microbiocide, Fungicide, Algicide
Unclassified pesticide
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-
Synthetic
Broad spectrum antimicrobial activity
10222-01-2
233-539-7
-
101801
25059
No data found
241.87
-
2,2-dibromo-2-cyanoacetamide
2,2-dibromo-3-nitrilopropionamide
PAN Bad Actor, Potential groundwater contaminant
-
Not applicable
Not applicable
Not applicable
Not applicable
-
White-yellow powdery solid with mild antiseptic odour
Slimicide 508 XD-7287L Antimicrobial Aqucar Dowicil Sump buddy
Formulations include tablets and both solid and liquid soluble concentrates.
15000
High
350000
Acetone
-
250000
Ethanol
-
123
-
-
-
-
190
-
-
-
-
6.31 X 1000
Calculated
-
0.80
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
-
-
Known soil and groundwater metabolites
None
dibromoacetonitrile
-
Water (Hydrolysis)
0.55
-
dibromoacetic acid
-
Water (a = Hydrolysis, pH 5), (b = Photolysis)
a=0.30, b=0.64
-
cyanoacetamide
-
Water
-
-
bromoacetamide
-
Water
-
-
oxalic acid
-
Water
-
-
ammonia
-
-
-
-
Terrestrial ecotoxicology
235
Rat
Moderate
-
-
-
-
-
-
-
-
150
Anas platyrhynchos
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1.0
Oncorhynchus mykiss
Moderate
0.47
Oncorhynchus mykiss
Moderate
0.90
Daphnia magna
Moderate
0.02
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
235
Rat
Moderate
2000
Rat
-
0.32
Rat
-
Intravenous LD₅₀ = 10 mg kg⁻¹
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
?Possibly, status not identified
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May cause breathing difficulties
Corrosive Not expected to autoignite; Not highly flammable
-
Not listed
-
-
2,2-dibromo-3-nitrilopropionamide
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-
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-
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Record last updated:
05/06/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242