4,4-methylenedianiline
Last updated: 16/03/2023
(Also known as: DADPM; MDA; methylenedianiline; diaminodiphenylmethane)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An industrially produced compound that is not known to occur naturally but used fior making foams, coating materials and resins
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-
Not applicable
Not applicable
Not applicable
EC Regulation 1107/2009 (repealing 91/414)
Not applicable
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
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C₁₃H₁₄N₂
C1=CC(=CC=C1CC2=CC=C(C=C2)N)N
No data
YBRVSVVVWCFQMG-UHFFFAOYSA-N
InChI=1S/C13H14N2/c14-12-5-1-10(2-6-12)9-11-3-7-13(15)8-4-11/h1-8H,9,14-15H2
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
4,4-methylenedianiline
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Other substance
Foam
Diaminodiphenylmethane
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Synthetic
Not applicable
101-77-9
202-974-4
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198.26
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bis(4-aminophenyl)methane
4,4-methylenedianiline
Potential groundwater pollutant; Marine pollutant; PAN Bad Actor Chemical
-
Not applicable
Not applicable
Not applicable
Not applicable
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Pale yellow to light brown crystalline powder
1000
High
2730000
Acetone
-
90000
Benzene
-
7000
Carbon tetrachloride
-
1430000
Methanol
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92.5
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
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399
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
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3.89 X 1001
Calculated
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1.59
Low
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-
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-
1.07
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-
Weak base
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-
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-
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-
-
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Soil adsorption and mobility
-
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-mobile
4753
Koc range 3825 to 5681mL g⁻¹
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Cannot be calculated
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None
Terrestrial ecotoxicology
620
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Moderate
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148
Agelaius phoeniceus
Moderate
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> 444
Eisenia foetida
Moderate
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-
-
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39.0
Oncorhynchus mykiss
Moderate
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2.3
Daphnia magna
Moderate
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-
-
-
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-
-
-
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21
Scenedemus subspicatus
Low
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-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
620
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Moderate
200
Rabbit
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
✓Yes, known to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
?Possibly, status not identified
?Possibly, status not identified
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
Immunotoxicant Cardiovascular or blood toxicant Kidney toxicant Mutagenic
Incompatible with strong acids & strong oxidising agents
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None - not a ppp
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4,4-methylenedianiline
-
4,4'-Diaminodiphenylmethan
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Record last updated:
16/03/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242