N-methyl-2-pyrrolidone
Last updated: 16/03/2023
(Also known as: NMP; m-pyrol)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A polar solvent with handling properties valuable in many pesticide formulations
Unknown
-
Not applicable
Not applicable
Not applicable
EC Regulation 1107/2009 (repealing 91/414)
Not applicable
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
-
C₅H₉NO
CN1CCCC1=O
No data
SECXISVLQFMRJM-UHFFFAOYSA-N
InChI=1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
Yes
Other substance
Solvent
Cyclic amide
-
-
Synthetic
Inert
872-50-4
212-828-1
-
-
-
99.13
-
1-methylpyrrolidin-2-one
N-methyl-2-pyrrolidone
PAN Bad Chemical Actor
-
Not applicable
Not applicable
Not applicable
Not applicable
-
Clear, colourless oily liquid
1000000
High
Miscible
Acetone
-
Miscible
Ethyl acetate
-
Miscible
Ethanol
-
Miscible
Benzene
-
-24.4
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
203
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
-
-
95
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
3.47 X 10-01
Calculated
-
-0.46
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Low
-
-
-
-
-
-
1.028
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
-
205nm = Log E 3.46
-
-
-
-
-
8.0
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-persistent
8.0
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-persistent
-
-
-
-
-
-
-
-
-
-
-
-
Literature states DT₅₀ 4.0 days clay, 8.7 days loam, and 11.5 days sand
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
-
-
-
-
-
None
Terrestrial ecotoxicology
3914
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 4000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Unknown species
Low
-
-
-
> 1000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Daphnia magna
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 500
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Unknown species
Low
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
3914
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Low
8000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rabbit
-
5.1
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Rat 4 hr
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
XNo, known not to cause a problem
?Possibly, status not identified
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Causes irritation to the gastrointestinal tract May cause corneal clouding Possible kidney toxicant May cause dermatitis
Flammable Explosive air-vapour mixes may form Incompatible with strong oxidants and acids
-
Not listed (Not listed)
-
-
-
N-methyl-2-pyrrolidone
-
-
-
-
-
-
-
-
-
-
-
Record last updated:
16/03/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242