Methiozolin (Ref: MRC-01)
Last updated: 24/01/2023
(Also known as: metiozolin)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A herbicide for turf and particularly useful for control of annual bluegass (Poa annua ).
Annual bluegrass and other grass weeds
Turf; Sports greens
-
Current
2008; 2010 first registered in Korea
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
Methiozolin is a chiral molecule occurring in the R- and S-forms. Commercially it is sold as a an isomeric herbicide.
C₁₇H₁₇F₂NO₂S
CC1=C(SC=C1)C2=NOC(C2)(C)COCC3=C(C=CC=C3F)F
No data
OPEJGICLTMWFNQ-UHFFFAOYSA-N
InChI=1S/C17H17F2NO2S/c1-11-6-7-23-16(11)15-8-17(2,22-20-15)10-21-9-12-13(18)4-3-5-14(12)19/h3-7H,8-10H2,1-2H3
Yes
Herbicide
Isoxazoline herbicide; Oxazole herbicide
-
-
Synthetic
Root uptake, slow acting, strongly inhibits plant cell wall biosynthesis in susceptible grasses
403640-27-7
No data found
None allocated
-
11500973
No data found
337.38
rac-(5R)-5-{[(2,6-difluorophenyl)methoxy]methyl}-5-methyl-3-(3-methylthiophen-2-yl)-4,5-dihydro-1,2-oxazole
(5RS)-5-[(2,6-difluorobenzyloxy)methyl]-4,5-dihydro-5-methyl-3-(3-methyl-2-thienyl)-1,2-oxazole
5-[[(2,6-difluorophenyl)methoxy]methyl]-4,5-dihydro-5-methyl-3-(3-methyl-2-thienyl)isoxazole
-
-
Q
30
Not applicable
Not applicable
None identified
-
Usually supplied as an emulsifiable concentrate
3.4
R4 R = Peer reviewed scientific publications 4 = Verified data
Low
1000
R4 R = Peer reviewed scientific publications 4 = Verified data
Acetone
-
560
R4 R = Peer reviewed scientific publications 4 = Verified data
Methanol
-
26
R4 R = Peer reviewed scientific publications 4 = Verified data
Hexane
-
50.2
R4 R = Peer reviewed scientific publications 4 = Verified data
-
402.7
-
-
-
-
197.4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
49
R4 R = Peer reviewed scientific publications 4 = Verified data
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
DT₅₀ range 46.8 to 51.7 days
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
-
-
-
-
-
None
Terrestrial ecotoxicology
> 2500
R4 R = Peer reviewed scientific publications 4 = Verified data
Rat
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 1000
Eisenia foetida
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 100
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1.53
R4 R = Peer reviewed scientific publications 4 = Verified data
Oncorhynchus mykiss
Moderate
-
-
-
2.04
R4 R = Peer reviewed scientific publications 4 = Verified data
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2.88
R4 R = Peer reviewed scientific publications 4 = Verified data
Selenastrum capricornutum
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 2500
R4 R = Peer reviewed scientific publications 4 = Verified data
Rat
Low
2500
R4 R = Peer reviewed scientific publications 4 = Verified data
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
No further information available
No information available
-
Not listed (Not listed)
-
-
-
methiozolin
-
-
-
-
-
-
-
-
-
-
-
Record last updated:
24/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242