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isolan (Ref: ENT 19060)
** isolane ** Geigy G-23611 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for isolan

Description: An obsolete, mainly experimental, carbamate insecticide with rapid knockdown contact and fumigant action.

Example pests controlled: Aphids, Houseflies, Oriental fruitfly; Thrips; Mites; Bedbugs

Example applications: Citrus fruits and other crops

Efficacy & activity: -

Availability status: Obsolete

Introduction & key dates: 1952, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires Not applicable
EU Candidate for substitution (CfS) Not applicable
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C10H17N3O2
Canonical SMILES CC1=NN(C(=C1)OC(=O)N(C)C)C(C)C
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) RNNBHZYEKNHLKT-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C10H17N3O2/c1-7(2)13-9(6-8(3)11-13)15-10(14)12(4)5/h6-7H,1-5H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Fumigant
Substance group Carbamate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Systemic. Cholinesterase inhibitor.
CAS RN 119-38-0
EC number 204-318-2
CIPAC number 104
US EPA chemical code 511500
PubChem CID 8393
Molecular mass (g mol-1) 211.26
PIN (Preferred Identification Name) 3-methyl-1-(propan-2-yl)-1H-pyrazol-5-yl dimethylcarbamate
IUPAC name (5-methyl-2-propan-2-ylpyrazol-3-yl) N,N-dimethylcarbamate
CAS name dimethyl-5-(1-isopropyl-3-methyl-pyrazolyl)carbamate
Other status information PAN Bad Chemical Actor
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1A
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Myzus persicae
Physical state Colourless liquid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Ciba Geigy
Example products using this active
  • Primin
  • Saolan
  • Isolan
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details No longer available.


ENVIRONMENTAL FATE

for isolan

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 1000000 V3 High
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting point (oC) - - -
Boiling point (oC) 301 Q3 -
Degradation point (oC) - - -
Flashpoint (oC) 136 Q3 -
Octanol-water partition coefficient at pH 7, 20oC P 4.47 X 1001 Calculated -
Log P 1.65 V3 Low
Bulk density (g ml-1)/Specific gravity 1.1 Q3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) - - -
Henry's law constant at 25oC (Pa m3 mol-1) - - -
GUS leaching potential index Click here for a note on the limitations of the GUS index 5.23 Calculated High leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 7.36 X 10+00 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 Does not absorb at wavelengths >290 nm V3 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 500 Q2 Very persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Stable in soil, still detectable after 500 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value Stable V3 -
Note Stable under normal environmental temperatures and pH
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stabe V3 -
Note Stable under normal environmental temperatures and pH
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - V3 Moderately mobile
Koc 115
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for isolan

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk Q3 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 10.8 V3 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 7.94 CA3 Sturnus vulgaris High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) > 10.70 F4 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0125 F4 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for isolan

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 10.8 V3 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) > 5600 V3 Rat -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Negligible risk since isolan is no longer produced or used
Occupational Negligible risk since isolan is no longer produced or used
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

-

General human health issues Toxic by ingestion, skin contact and intraperitoneal routes

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Store ventilated, at low-temperatures and keep dry
IMDG Transport Code is usually 6.1
CLP classification 2013 -
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Very toxic: R27, R28
EC Safety Classification Click here to view information omn the EU safety phrases S28, S36/37/39, S45
WHO Classification NL - Not listed
US EPA Classification (formulation) - -
UN Number 2992
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group I (great danger)


TRANSLATIONS

for isolan

Language Name
English isolan
French isolane
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian -
Polish -
Swedish -
Hungarian -
Dutch -

Record last updated: Thursday 31 May 2018
Contact: aeru@herts.ac.uk