Coumachlor
Last updated: 14/01/2023
(Not known by any other names)
Coumachlor is a first generation rodenticide which is now largely obsolete. There are many gaps in the available data, however, It has a low aqueous solubility and is not volatile. It is highly toxic to birds and aquatic invertebrates. It also has a high oral toxicity to mammals.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An obsolete coumarin rodenticide
Rats; Mice; Other small rodents
Rats; Mice; Other small rodents
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Considered obsolete but may be available in some countries
circa 1952
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Poland
Expired
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
A chiral molecule. Coumachlor is racemic.
C₁₉H₁₅ClO₄
CC(=O)CC(C1=CC=C(C=C1)Cl)C2=C(C3=CC=CC=C3OC2=O)O
-
DEKWZWCFHUABHE-UHFFFAOYSA-N
InChI=1S/C19H15ClO4/c1-11(21)10-15(12-6-8-13(20)9-7-12)17-18(22)14-4-2-3-5-16(14)24-19(17)23/h2-9,15,22H,10H2,1H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
coumachlor
Unstated isomer
Rodenticide
Coumarin rodenticide
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-
Synthetic
1st generation anticoagulant, blocks formation of prothrombin, inhibits blood coagulation causing death by internal haemorrhage
81-82-3
201-378-1
188
224200
54682651
607-057-00-6
342.77
rac-3-[(1R)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one
3-[(1RS)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxycoumarin
3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one
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-
Not applicable
Not applicable
Not applicable
Not applicable
-
Off-white crystalline powder
Usually supplied as bait or tracking powders
1.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
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170
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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-
-
-
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1.35 X 1004
Calculated
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4.13
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
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1.38
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
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-
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0.013
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
1.71 X 10-08
Non-volatile
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Soil adsorption and mobility
-
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-mobile
13440
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Cannot be calculated
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None
Terrestrial ecotoxicology
16
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
High
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>> 4.3
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Colinus virginianus
High
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> 340
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Lepomis macrochirus
Low
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0.001
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
High
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HUMAN HEALTH AND PROTECTION
High (class III)
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16
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
High
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
May cause pulmonary edema Potential dyspnea on exertion May cause blood coagulation disturbance resulting in hematomata
No information available
Health: H373 Environment: H412
Not classified: Obsolete
-
-
coumachlor
coumachlore
Coumachlor
coumachlor
cumacloro
cumacloro
coumachlor
kumachlor
-
-
cumachloor
-
Record last updated:
14/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242