Demeton-S-methyl
Last updated: 15/01/2023
(Also known as: methyl-mercaptophos-teolovy; methyl demeton; mercapthphos)
Demeton-S-methyl is an insecticide and acaricide. It is highly soluble in water, volatile and, based on its physico-chemical data, it is not expected to leach to groundwater. It is not persistent in soil systems. Demeton-S-methyl is highly toxic to mammals, a cholinesterase inhibitor, a neurotoxin and a recognised irritant. It is highly toxic to birds, aquatic invertebrates and honey bees and moderately toxic to most other species including fish and earthworms.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An insecticide used to control aphids and other sucking insects on a range of crops
Aphids including woolly aphids, citrus aphids, Russian aphids; Sawflies; Bryobia mites; Lacebugs
Vegetables including beans, peas, brassicas, peppers, aubergines, onions; Fruit including olives, peaches, plums, apricots; Tomatoes; Cotton; Peanuts; Wheat; Maize; Sorghum
-
-
1957
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Expired
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
The methyl ester of the S-form of isomeric demeton
C₆H₁₅O₃PS₂
CCSCCSP(=O)(OC)OC
No data
WEBQKRLKWNIYKK-UHFFFAOYSA-N
InChI=1S/C6H15O3PS2/c1-4-11-5-6-12-10(7,8-2)9-3/h4-6H2,1-3H3
Yes
Insecticide, Acaricide
Organophosphate insecticide; Organothiophosphate insecticide; Organophosphate acaricide; Organothiophosphate acaricide
-
-
Synthetic
Systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
919-86-8
213-052-6
47
-
13526
015-031-00-5
230.29
S-[2-(ethylsulfanyl)ethyl] O,O-dimethyl phosphorothioate
S-2-ethylthioethyl O,O-dimethyl phosphorothioate
S-(2-(ethylthio)ethyl) O,O-dimethyl phosphorothioate
PAN Bad Actor Chemical; Subject to the provisions of the UK Poisons Act 1972
-
Not applicable
Not applicable
1B
Not applicable
Aphis gossypii , Panonychus ulmi , Tetranychus urticae , Tetranychus viennensis , Aculus cornutus , Aphis craccivora , many others
Yellow oil
Bayer CropScience Doo Yang Industrial Co. Ltd.
Metasystox Duratox DSM Demeton EC
Usually supplied as an emulsifiable concentrate.
22000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2.09 X 1001
Calculated
-
1.32
Low
-
-
-
-
-
-
1.21
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
40
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Highly volatile
4.19 X 10-04
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
2.7
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Non-persistent
2.7
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Non-persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3.0
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
-
Mango fruit, n=1
-
-
-
-
56
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately persistent
pH sensitive: DT₅₀ 63 days at pH 4, 8 days at pH 9 all at 22 °C
-
-
-
-
-
-
Soil adsorption and mobility
-
W3 W = French database provided by ARVALIS-Institut du Végétal 3 = Unverified data of known source
Moderately mobile
90
-
-
-
-
-
-
-
-
0.88
Calculated
Low leachability
1.95 X 10-03
Calculated
-
-
Low
Calculated
-
Moderately mobile
Calculated
-
0.5
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Based on LogP < 3
Low potential
Not available
-
Known groundwater metabolites
None
None
Terrestrial ecotoxicology
40
Rat
High
-
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 2 year
-
1
-
-
-
-
44
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Coturnix japonica
High
-
-
-
-
-
-
> 250
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Eisenia foetida
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2.6
Apis mellifera 24hr
Moderate
> 0.19
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Apis mellifera
High
-
-
-
-
-
-
> 2.68
R4 R = Peer reviewed scientific publications 4 = Verified data
Bombus terrestris 48 hr
Moderate
-
-
-
-
-
-
-
-
-
-
-
0.076
R4 R = Peer reviewed scientific publications 4 = Verified data
Megachile rotundata
High
Contact
-
-
-
-
-
-
-
-
-
-
-
-
-
Harmless
AB1 AB = SELECTV Database 1 = Estimated data with little or no verification
Typhlodromus pyri
-
-
-
-
> 6.4
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 0.023
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
22.1
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Scenedemus subspicatus
Low
10
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Unknown species
Low
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
40
Rat
High
30
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
0.13
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat (aerosol)
-
-
-
-
0.0003
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
-
-
-
List I; List II
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
Rapidly eliminated in urine
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E1 E = Unspecified genotoxicity type (miscellaneous data source) 1 = Positive
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
✓Yes, known to cause a problem
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
?Possibly, status not identified
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
No further information available
Combustible
Health: H301, H311 Environment: H411
Ib (Highly hazardous)
Usually 3018
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demeton-S-methyl
demeton-S-methyle
Demeton-S-methyl
demeton-S-methyl
demeton-s-metil
demeton-S-metil
demeton-S-methyl
demeton-S-metylowy
-
-
demeton-S-methyl
Record last updated:
15/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242