Kasugamycin
Last updated: 03/09/2023
(Also known as: kasugamycinic acid; crop antibiotic)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An aminoglycoside antibiotic used, normally as the hydrochloride salt, against bacteria and some fungi.
Bacterial rot (Erwinia atroseptica ); Leaf mold (Cladosporium fulvum ); Bacteria spot (Xanthomonas campestris, pv vesicatoria ), Rice blast; Scab
Tomatoes; Peppers; Rice; Potatoes; Sugar beet; Celery, Apples
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Current
1965
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Netherlands
Expired
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Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
India, Belize, Japan; Mexico, USA
Kasugamycin is a chiral molecule
C₁₄H₂₅N₃O₉
CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N
C[C@@H]1[C@H](C[C@@H]([C@H](O1)OC2[C@@H]([C@H](C([C@@H]([C@@H]2O)O)O)O)O)N)N=C(C(=O)O)N
PVTHJAPFENJVNC-MHRBZPPQSA-N
InChI=1S/C14H25N3O9/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24)/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-/m1/s1
Yes
Fungicide, Bactericide, Crop antibiotic, Other substance, Metabolite
Soil, Plant
Wood preservative
Micro-organism
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Natural
Contact action resulting in the inhibition of protein biosynthesis reducing bacterial growth and reproduction (bacteriostatic), rather than killing the bacteria directly.
6980-18-3
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230001
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391.38
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(5-amino-2-methyl-6-(2,3,4,5,6-pentahydroxycyclohexyloxy)tetrahydropyran-3-yl)amino-a-iminoacetic acid
3-O-(2-amino-4-((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-a-D-arabino-hexopyranosyl)-D-chiro-inositol
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Not applicable
Not applicable
Not applicable
24
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White, crystalline substance
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Usually supplied as the hydrochloride formulated as a wettable powder
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3.23
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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pKa(2) = 7.73, pKa(3) = 11.0
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Literature states that substance rapidly breaks down to form ammonia, water and carbon dioxide
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Soil adsorption and mobility
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Cannot be calculated
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Secondary metabolite
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Secondary metabolite
Known groundwater metabolites
None
kasuganobiosamine
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Plant
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ammonia Note: Secondary metabolite
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Plant
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oxalic acid Note: Secondary metabolite
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Plant
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Terrestrial ecotoxicology
21000
Mouse
Low
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> 4000
Colinus virginianus
Low
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> 1000
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Eisenia foetida
Low
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> 40
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Apis mellifera
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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21000
Mouse
Low
4000
Rat
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
?Possibly, status not identified
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
No further information available
No information available
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U (Unlikely to present an acute hazard)
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kasugamycin
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kasugamicina
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Record last updated:
03/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242