Buthidazole (Ref: Vel-5026)
Last updated: 16/03/2023
(Not known by any other names)
Buthidazole is a pre-emergence herbicide that is now considered obsolete. It is highly soluble in water and non-volatile. It can be moderately persistent in soil systems depending on local conditions. Very little ecotoxicity data is available. It is moderately toxic to humans if ingested.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A largely obsolete herbicide that was used for the pre-emergence or early emergence control of various broad-leaved weeds and grasses
Pigweed; Lambsquarters; Groundsel; Quackgrass
Corn; Alfalfa; Sugarcane
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Considered obsolete but may be available in some countries
1974, first reported
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
Buthidazole is a chiral molecule. The technical material is an isomeric mixture.
C₁₀H₁₆N₄O₂S
CC(C)(C)C1=NN=C(S1)N2C(CN(C2=O)C)O
No data
SWMGXKSQWDSBKV-UHFFFAOYSA-N
InChI=1S/C10H16N4O2S/c1-10(2,3)7-11-12-8(17-7)14-6(15)5-13(4)9(14)16/h6,15H,5H2,1-4H3
Yes
Herbicide
Unclassified pesticide
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Synthetic
Selective, contact, thought to be absorbed by roots and translocated to leaves
55511-98-3
259-685-1
None allocated
115901
41462
No data found
256.32
rac-(4R)-3-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-4-hydroxy-1-methylimidazolidin-2-one
(4RS)-3-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-4-hydroxy-1-methylimidazolidin-2-one
3-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-4-hydroxy-1-methyl-2-imidazolidinone
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Not known
Not known
Not applicable
Not applicable
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Colourless crystalline solid
Usually supplied as granules or as wettable powders
6500
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
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133
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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237
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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2.51 X 1003
Calculated
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3.4
High
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1.25
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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0.0053
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
2.09 X 10-07
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
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50
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately persistent
50
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately persistent
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General literature states DT₅₀ less than 50 days
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Soil adsorption and mobility
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Cannot be calculated
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Known soil and groundwater metabolites
None
N-(5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl)urea
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3-(5-(1,1-dimethylethyl)-1,3,4-thiadazol-2-yl)-4-hydroxy-2-imidazolidione
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3-(5-(1,1-diemthylethyl)-1,3,4-thiadazol-2-yl)-4,5-dihydroxy-2-imidazolidione
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N-(5-(1,1-dimethylethyl)-1,3,4-thiadazol-2-yl)-N-hydroxymethyl-N-methylurea
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-
Terrestrial ecotoxicology
1542
Rat
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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1542
Rat
Moderate
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
No further information available
No information available
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III (Slightly hazardous)
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buthidazole
buthidazole
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Record last updated:
16/03/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242