Afidopyropen (Ref: ME5343)
Last updated: 15/02/2023
(Also known as: coprapidpen; BAS 440 I)
Afidopyropen is an insecticide. It is moderately persistent in soil and water. It is moderately mobile and may leach to groundwaters. It has a favourable biodiversity toxcityl profile and is not highly toxic to bees. Whilst it has a low oral toxicity to mammals there are some conserns that afidopyropen may be carcinogenic.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An insecticide that is effective against sucking insects
Aphids; Spidermites; Whitefly; Thrips; Psyllids; Mealybugs, Scale
Fruit; Vegetables; Nuts; Cotton; Ornamentals
-
Current
2013
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
Isomeric
C₃₃H₃₉NO₉
CC12CCC(C(C1CC(C3(C2C(C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)O)(C)COC(=O)C6CC6)OC(=O)C7CC7
C[C@]12CC[C@@H]([C@@]([C@@H]1C[C@@H]([C@@]3([C@@H]2[C@H](C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)O)(C)COC(=O)C6CC6)OC(=O)C7CC7
LRZWFURXIMFONG-HRSIRGMGSA-N
InChI=1S/C33H39NO9/c1-31-11-10-24(42-29(38)18-8-9-18)32(2,16-40-28(37)17-6-7-17)22(31)14-23(35)33(3)27(31)26(36)25-21(43-33)13-20(41-30(25)39)19-5-4-12-34-15-19/h4-5,12-13,15,17-18,22-24,26-27,35-36H,6-11,14,16H2,1-3H3/t22-,23+,24+,26+,27-,31+,32+,33-/m1/s1
Yes
Insecticide
Pyropene insecticide; Organic heterotetracyclic compound
-
-
Synthetic
Disrupts insect feeding behaviour. A chlordotonal orgn TRPV (transient receptor potential vanilloid) channel modulatot
915972-17-7
815-966-6
None allocated
7969
54589430
No data found
593.7
-
((3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3-(cyclopropylcarbonyloxy)-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridyl)-11H,12H-benzo(f)pyrano(4,3-b)chromen-4-yl)methyl cyclopropanecarboxylate
((3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3-((cyclopropylcarbonyl)oxy)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridinyl)-2H,11H-naphtho(2,1-b)pyrano(3,4-e)pyran-4-yl)methyl cyclopropanecarboxylate
-
Possible groundwater pollutants
Not applicable
Not applicable
9D
Not applicable
-
The technical maaterial is a yellow powder
Sefina Versys Ventigra Inscalis
-
25.1
E4 E = Manufacturers safety data sheets 4 = Verified data
Low
55400
E4 E = Manufacturers safety data sheets 4 = Verified data
Toluene
-
500000
E4 E = Manufacturers safety data sheets 4 = Verified data
Methanol
-
500000
E4 E = Manufacturers safety data sheets 4 = Verified data
Acetone
-
500000
E4 E = Manufacturers safety data sheets 4 = Verified data
Ethyl acetate
-
150
E4 E = Manufacturers safety data sheets 4 = Verified data
-
-
-
-
-
-
-
-
-
-
2.82 X 1003
Calculated
-
3.45
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
High
-
-
-
-
-
-
-
-
-
-
-
-
-
9.99 X 10-03
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Low volatility
2.34 X 10-04
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Non-volatile
-
-
-
-
-
-
-
8.8
E4 E = Manufacturers safety data sheets 4 = Verified data
Non-persistent
8.8
E4 E = Manufacturers safety data sheets 4 = Verified data
Non-persistent
-
-
-
-
-
-
-
-
-
-
-
-
General literature: aerobic DT₅₀ 2.7-18.6 days
-
-
-
-
-
-
-
-
-
-
-
-
Stable
P3 P = Other non-EU, UK or US Governments and Regulators 3 = Unverified data of known source
Stable
Stable at all environmntally relevant pH values
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
-
-
-
-
-
None
Terrestrial ecotoxicology
> 2000
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
Low
-
-
-
-
-
-
-
-
> 802
E4 E = Manufacturers safety data sheets 4 = Verified data
Colinus virginianus
Moderate
-
-
-
-
-
-
> 1000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Eisenia foatida
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 200
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Apis mellifea
Low
> 100
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Apis mellifera
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
78.1
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Unknown species
-
140.4
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Unknown species
-
-
-
-
> 18.3
E4 E = Manufacturers safety data sheets 4 = Verified data
Pimephales promelas
Moderate
-
-
-
> 8.0
E4 E = Manufacturers safety data sheets 4 = Verified data
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 2000
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
Low
2000
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
-
> 5.48
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
?Possibly, status not identified
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
XNo, known not to cause a problem
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
No information available
Not explosive or oxidising Not expected to autoignite; Not highly flammable
-
Not listed
-
-
afidopyropen
afidopyropene
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Record last updated:
15/02/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242