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etridiazole (Ref: Olin 2424)
** echlomezol ** ethazol ** athazole ** terrazole ** OM 2424 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for etridiazole

Description: A fungicide for soil or compost incorporation to control mainly Phytophthora and Pythium spp.

Example pests controlled: Phytophthora, Pythium spp.; Damping off; Powdery mildew

Example applications: Field crops; Vegetables; Ornamentals; Lawns; Tomato and other vegetable seedlings

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1972

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Netherlands/Spain
Date inclusion expires 31/05/2021
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C5H5Cl3N2OS
Canonical SMILES CCOC1=NC(=NS1)C(Cl)(Cl)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) KQTVWCSONPJJPE-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide
Substance group Aromatic hydrocarbon
Minimum active substance purity 970 g/kg
Known relevant impurities EU dossier - none declared
Substance origin Synthetic
Mode of action Contact with protective and curative action. Lipid peroxidation inhibitor.
CAS RN 2593-15-9
EC number 219-991-8
CIPAC number 518
US EPA chemical code 084701
PubChem CID 17432
Molecular mass (g mol-1) 247.53
PIN (Preferred Identification Name) 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole
IUPAC name ethyl 3-trichloromethyl-1,2,4-thiadiazol-5-yl ether
CAS name 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 14
Examples of recorded resistance -
Physical state Clear colourless to reddish brown semi-solid
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • AgriGuard
  • Standon
  • Scotts
  • Ollin
  • Mallinckrodt
Example products using this active
  • Terraguard
  • Aaterra
  • Pansoil
  • Truban
  • Dwell
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Often supplied as a wettable powder, emulsifiable concentrate or dust.


ENVIRONMENTAL FATE

for etridiazole

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 88.9 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) Miscible A5 - Xylene -
Miscible A5 - Ethanol -
Miscible A5 - Methanol -
Miscible A5 - Hexane -
Melting point (oC) 22 A5 -
Boiling point (oC) 113 A3 -
Degradation point (oC) - - -
Flashpoint (oC) 111 A5 -
Octanol-water partition coefficient at pH 7, 20oC P 2.34 X 1003 Calculated -
Log P 3.37 A5 High
Bulk density (g ml-1)/Specific gravity 1.497 A5 -
Dissociation constant (pKa) at 25oC 2.77 A5 -
Note: Very weak base
Vapour pressure at 20oC (mPa) 1430 A5 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 3.02 A5 Moderately volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.47 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.86 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Maxima 220nm = 5444 A5 -
Surface tension (mN m-1) 71.9 A5 at 22oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 20 M4 Non-persistent
DT50 (lab at 20oC) 8.98 A5 Non-persistent
DT50 (field) - - -
DT90 (lab at 20oC) 72.5 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies range 2.22 (loam) - 45.5 (sandy loam) days, DT90 range 7.4-194 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 0.04 K3 Fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 98 A5 Moderately persistent
Note Slightly sensitive to pH: DT50 92 days at pH 5, 88 days at pH 9 all at 25 degC
Water-sediment DT50 (days) 1.85 A5 Fast
Water phase only DT50 (days) 1.31 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - DW3 Slightly mobile
Koc 1000
Notes and range -
Freundlich Kf 7.17 A5 Moderately mobile
Kfoc 289
1/n 0.873
Notes and range EU dossier Kf range 5.06-8.24 mL/g, Kfoc range 195-349 mL/g, 1/n range 0.84-0.92, Soils=3
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
dichloroetridiazole This metabolite may cause environmental pollution, click here for further information Soil   0.133   Major fraction, Relevant
etridiazole acid Soil   0.067   Minor fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
5-hydroxymethyl etridiazole - Rat - -
5-hydroxyethoxy etridiazole acid - Rat - -
N-carbethoxy oxamic acid - Rat (Urinary) - -
ethyl (aminocarbamyl) carbamate - Rat (Urinary) - -
oxalic acid - Rat (Urinary) - -
etridiazole carboxylic acid - Rat (Urinary) - -
3-hydroxymethyl etridiazole - Rat - -


ECOTOXICOLOGY

for etridiazole

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 165 A5 Threshold for concern
CT50 (days) 1 -
Mammals - Acute oral LD50 (mg kg-1) > 945 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) 2.7 A5 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 560 A5 Colinus virginianus Moderate
Birds - Short term dietary (LC50/LD50) 286 mg kg bw-1 day-1 A3 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 2.4 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.12 A5 Oncorhynchus mykiss Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 3.1 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.37 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 2.5 A5 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 7.3 A5 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.3 A5 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) 0.32 Q2 Unknown species Moderate
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect 96 Mortality
Dose: 14.4 kg ha-1
A5 Aphidius rhopalosiphi, adult
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 96 Mortality
Dose: 14.4 kg ha-1
A5 Typhlodromus pyri, protonymph
-
Soil micro-organisms Nitrogen mineralisation: Chronic effect
Carbon mineralisation: Chronic effect
A3
Dose: Not stated
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for etridiazole

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 945 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.7 A5 Rat (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.015 A4 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.15 A4 Rabbit, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.03 A4 Dog, SF=100 -
Dermal penetration studies (%) 18-30 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Bystanders should be prohibited from entering glasshouses post-application
Occupational PPE/PPC required to minimise exposure
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; Calc MAC=15.0 μg l-1; A5 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Possible liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H302, H312, H331, H351
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Carcinogen category 3: R40
T - Toxic: R23, Xn - Harmful: R21, R22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S36/37, S38, S45, S60, S61
WHO Classification III - Slightly hazardous
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number Usually 2810
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group II (medium danger)


TRANSLATIONS

for etridiazole

Language Name
English etridiazole
French etridiazole
German Etridiazol
Danish etridiazole
Italian etridiazolo
Spanish etridiazol
Greek -
Slovenian etridiazol
Polish etridiazol
Swedish -
Hungarian -
Dutch etridiazool

Record last updated: Thursday 23 August 2018
Contact: aeru@herts.ac.uk