Probenazole
Last updated: 24/01/2023
(Also known as: PBZ)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
A benoxthiazole fungicide widely used to control rice blast in paddy fields in Japan
Rice blast; Rice brown spot (Cochliobolus miyabeanus ); Leaf spot (Cercospora capsici ); Powdery mildew (Oidiopsis sicula ), Bacteria blight (Xanthomonas oryzae ); Black rot (Xanthomonas campestris ); Soft rot (Pseudomonas caratovora )
Rice; Peppers; Cabbage; Lettuce; Broccoli; Onion
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Current
1975
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₁₀H₉NO₃S
C=CCOC1=NS(=O)(=O)C2=CC=CC=C21
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WHHIPMZEDGBUCC-UHFFFAOYSA-N
InChI=1S/C10H9NO3S/c1-2-7-14-10-8-5-3-4-6-9(8)15(12,13)11-10/h2-6H,1,7H2
Yes
Fungicide, Bactericide, Wood preservative
Benzisothiazole fungicide
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-
Synthetic
Induces systemic acquired resistence - plant defense activator
27605-76-1
608-113-2
None allocated
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91587
No data found
223.25
3-(prop-2-en-1-yloxy)-1lambda6,2-benzothiazole-1,1-dione
3-allyloxy-1,2-benzothiazole 1,1-dioxide
3-(2-propen-1-yloxy)-1,2-benzisothiazole 1,1-dioxide
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-
Not applicable
Not applicable
Not applicable
P02
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Usually supplied in a granular formulation
150
Moderate
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138.5
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2.51 X 1001
Calculated
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1.4
Low
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2.1
R4 R = Peer reviewed scientific publications 4 = Verified data
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Published literature RL₅₀ range 1.7-2.4 days, rice leaves & straw, n=2
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Soil adsorption and mobility
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Cannot be calculated
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Known soil and groundwater metabolites
None
1,2-benzosothiazole-3-(2H)-one, 1,1-dioxide
BIT
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Terrestrial ecotoxicology
2030
Rat
Low
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HUMAN HEALTH AND PROTECTION
High (class III)
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2030
Rat
Low
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Intraperitoneal LD₅₀ = 850 mg kg⁻¹
Rat
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Subcutaneous LD₅₀ > 5000 mg kg⁻¹
Rat
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
No further information available
No information available
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O (Obsolete substance)
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probenazole
probenazole
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Record last updated:
24/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242