Chloral hydrate
Last updated: 22/01/2023
(Also known as: aquachloral; chorhydrate)
Chloral hydrate is an obsolete herbicide. It is a highly volatile substance which is not highly toxic to aquatic species. Chloral hydrate is moderately toxic to mammals if ingested. It is also carcinogenic and an irritasnt/
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An obsolete herbicide that was used, pre-emergence/pre-sowing to control grass weeds
Couch; Millet; Wild oats; Foxtails
Field crops
-
Considered obsolete but may be available in some countries
1832, first discovered Germany
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₂H₃Cl₃O₂
C(C(Cl)(Cl)Cl)(O)O
-
RNFNDJAIBTYOQL-UHFFFAOYSA-N
InChI=1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
chloral hydrate
-
Herbicide, Veterinary substance
Organochloride herbicide
-
-
Synthetic
-
302-17-0
206-117-5
None allocated
268100
2707
605-014-00-6
165.42
2,2,2-trichloroethane-1,1-diol
2,2,2-trichloroethane-1,1-diol
2,2,2-tricloro-1,1-ethandiol
-
-
Not known
Not known
Not applicable
Not applicable
-
Colourless crystals, hygroscopicith characteristic odour
Chemiekombinat Bitterfield
Usually formulated as an aqueous solution
3830000
High
-
-
-
51.6
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
98.0
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
97.0
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
9.77 X 1000
Calculated
-
0.99
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
Low
Likely to be soluble
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
Based on chemical group
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
1.91
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
6.8
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
-
4.7 X 1006
Highly volatile
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Known groundwater metabolites
None
None
Terrestrial ecotoxicology
1080
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
200
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Perca fluviatilis
Low
-
-
-
> 245
Daphnia magna
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
-
-
-
1080
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
3030
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
Intraperitoneal LD₅₀ = 472 mg kg⁻¹
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
Hetaptic metabolism. Excreted in the bile, faeces & urine
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
Carcinogen
Endocrine disruptor
✓Yes, known to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E2 E = Unspecified genotoxicity type (miscellaneous data source) 2 = Mixed/ambiguous results
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
May induce sedative & hypnotic effects CNS & heart toxicant May cause diarrhoea, dizziness and nausea Possible liver & kidney toxicant
Slightly corrosive to metals Incompatible with strong bases and oxidisers
-
NL (Not listed)
-
-
chloral hydrate
hydrate de chloral
Chloraldurat
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-
-
-
-
-
-
-
Record last updated:
22/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242