broflanilide (Ref: MCI-8007) |
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GENERAL INFORMATION
for broflanilide
Description: A novel meta-diamide organo-halide insecticide that has larvicidal activity against many chewing pests
Example pests controlled: Chewing insect pests including termites, roaches and Spodoptera litura
Example applications: -
Efficacy & activity: -
Availability status: Novel
Introduction & key dates: 2014
EC Regulation 1107/2009 (repealing 91/414):
Status | Not approved |
Dossier rapporteur/co-rapporteur | Not applicable |
Date inclusion expires | Not applicable |
EU Candidate for substitution (CfS) | Not applicable |
Listed in EU database | No |
Approved for use () or known to be used (
) in the following European countries:
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
Isomerism | - |
Chemical formula | C25H14BrF11N2O2 |
Canonical SMILES | CN(C1=CC=CC(=C1F)C(=O)NC2=C(C=C(C=C2Br)C(C(F)(F)F)(C(F)(F)F)F)C(F)(F)F)C(=O)C3=CC=CC=C3 |
Isomeric SMILES | No data |
International Chemical Identifier key (InChIKey) | QSLZKWPYTWEWHC-UHFFFAOYSA-N |
International Chemical Identifier (InChI) | InChI=1S/C25H14BrF11N2O2/c1-39(21(41)12-6-3-2-4-7-12)17-9-5-8-14(18(17)27)20(40)38-19-15(23(29,30)31)10-13(11-16(19)26)22(28,24(32,33)34)25(35,36)37/h2-11H,1H3,(H,38,40) |
2D structure diagram/image available? | Yes |
Pesticide type | Insecticide, Larvicide | |||
Substance group | Diamide | |||
Minimum active substance purity | - | |||
Known relevant impurities | - | |||
Substance origin | Synthetic | |||
Mode of action | Acts as a noncompetitive resistant-to-dieldrin (RDL) gamma-aminobutyric acid (GABA) receptor antagonist | |||
CAS RN | 1207727-04-5 | |||
EC number | - | |||
CIPAC number | - | |||
US EPA chemical code | - | |||
PubChem CID | 53341374 | |||
Molecular mass (g mol-1) | - | |||
PIN (Preferred Identification Name) | N-(2-bromo-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide | |||
IUPAC name | 6'-bromo-α,α,α,2-tetrafluoro-3-(N-methylbenzamido)-4'-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)benz-o-toluidide | |||
CAS name | 3-(benzoylmethylamino)-N-(2-bromo-4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide | |||
Other status information | - | |||
Relevant Environmental Water Quality Standards | - | |||
Herbicide Resistance Classification (HRAC) | Not applicable | |||
Herbicide Resistance Classification (WSSA) | Not applicable | |||
Insecticide Resistance Classification (IRAC) | - | |||
Fungicide Resistance Classification (FRAC) | Not applicable | |||
Examples of recorded resistance | - | |||
Physical state | - | |||
Related substances & organisms | - |
Formulations:
ENVIRONMENTAL FATE
for broflanilide
Property ![]() |
Value | Source/Quality Score/Other Information ![]() |
Interpretation ![]() |
|
Linear | Kd | - | - | - |
Koc | - | |||
Notes and range | - | |||
Freundlich | Kf | - | - | - |
Kfoc | - | |||
1/n | - | |||
Notes and range | - | |||
pH sensitivity | - |
ECOTOXICOLOGY
for broflanilide
HUMAN HEALTH AND PROTECTION
for broflanilide
General:
Property ![]() |
Value | Source/Quality Score/Other Information ![]() |
Interpretation ![]() |
|
Threshold of Toxicological Concern (Cramer Class) ![]() |
High (class III) | - | - | |
Mammals - Acute oral LD50 (mg kg-1) | - | - | - | |
Mammals - Dermal LD50 (mg kg-1 body weight) | - | - | - | |
Mammals - Inhalation LC50 (mg l-1) | - | - | - | |
Other Mammal toxicity endpoints | - | - | ||
ADI - Acceptable Daily Intake (mg kg-1bw day-1) | - | - | - | |
ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
Dermal penetration studies (%) | - | - | - | |
Dangerous Substances Directive 76/464 | - | - | - | |
Exposure Routes | Public | - | ||
Occupational | - | |||
European MRLs | Click here for the EU MRL pesticide database | |||
Drinking Water Standards | - | - | - | |
Drinking Water MAC (μg l-1) | - | - | - |
Health issues:
Carcinogen | Genotoxic | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
- |
A0; B0; C0; D0; E0 | - |
- |
- |
- |
|||
Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
- |
- |
- |
- |
- |
|
|||
General human health issues | No information available | |||||||
Key: Genotoxicity A: Chromosome aberration (EFSA database) B: DNA damage/repair (EFSA database) C: Gene mutation (EFSA database) D: Genome mutation (EFSA database) E: Unspecified genotoxicity type (miscellaneous data source) 0: No data 1: Positive 2: Mixed/ambiguous results 3: Negative |
Key: Other![]() ![]() ![]() - : No data found |
Handling issues:
Language | Name |
English | broflanilide |
French | broflanilide |
German | - |
Danish | - |
Italian | - |
Spanish | - |
Greek | - |
Slovenian | - |
Polish | - |
Swedish | - |
Hungarian | - |
Dutch | - |
Record last updated: Friday 01 June 2018
Contact: aeru@herts.ac.uk