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GET ADDITIONAL DATA HERE!

24-epibrassinolide
** epibrassinolide ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for 24-epibrassinolide

Description: An activator that enhances the plants ability to protect against abiotic stresses and to improve plant health. Although it is effective against some fungal infections it has no direct fungicidal or antagonistic effects.

Example pests controlled: Grey mould; Downy mildew; Bottom rot; Leaf spot; Salt stress

Example applications: Wine and table grapes; Leafy vegetables e.g. endive, chicory, spinach; Pumpkin; Lettuce; Cucumber; Sugarbeet

Efficacy & activity: Effectiveness demonstrated in plant trials. Disease severity and incidence tend to be reduced rather than cured.

Availability status: Current

Introduction & key dates: -

EC Regulation 1107/2009 (repealing 91/414):
Status Pending
Dossier rapporteur/co-rapporteur Austria
Date inclusion expires -
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: USA (pending)

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism A brassinosteroid isomer
Chemical formula C28H48O6
Canonical SMILES CC(C)C(C)C(C(C(C)C1CCC2C1(CCC3C2COC(=O)C4C3(CC(C(C4)O)O)C)C)O)O
Isomeric SMILES -
International Chemical Identifier key (InChIKey) IXVMHGVQKLDRKH-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Elicitor and Plant activator; Fungicide
Substance group Plant hormone
Minimum active substance purity 900 g/kg
Known relevant impurities EU dossier 2018: None declared
Substance origin Natural
Mode of action An elicitor of the plantís self-defence mechanisms against fungal diseases
CAS RN 78821-43-9
EC number -
CIPAC number -
US EPA chemical code -
PubChem CID -
Molecular mass (g mol-1) 480.68
PIN (Preferred Identification Name) (22R,23R,24R)-2a,3a,22,23-tetrahydroxy-24-methyl-Ŗ-homo-7-oxa-5-cholestan-6-one
IUPAC name (22R,23R,24R)-2a,3a,22,23-tetrahydroxy-24-methyl-Ŗ-homo-7-oxa-5-cholestan-6-one
CAS name 24-epibrassinolide
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state White to cream coloured powdery solid
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Suntton
Example products using this active
  • Sunergist
UK LERAP status No UK approval for use
Formulation and application details -


ENVIRONMENTAL FATE

for 24-epibrassinolide

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 3.8 A5 - @ pH 4.5 Low
Solubility - In organic solvents at 20oC (mg l-1) 28700 A5 - Methanol -
3.1 A5 - n-Heptane -
5500 A5 - Ethyl acetate -
18000 A5 - Acetone -
Melting point (oC) 254.6 A5 -
Boiling point (oC) >400 A3 -
Degradation point (oC) >400 A3 -
Flashpoint (oC) Not expected to self-ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.00 X 1002 Calculated -
Log P 2.0 A4 - @ 30 degC Low
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC No dissociation A5 -
Note:
Vapour pressure at 20oC (mPa) 1.9 X 10-12 A3 - Estimated Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.40 X 10-13 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index - - -
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value - - -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - - -
Maximum UV-vis absorption L mol-1 cm-1 pH 5.5: 205nm=183, 215nm=91.0
pH 0.6: 200nm=245
pH 13.4: 219nm=67
A5 -
Surface tension (mN m-1) 68 A5 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability Nor readily biodegradable
Soil degradation (days) (aerobic) DT50 (typical) 34.4 A5 Moderately persistent
DT50 (lab at 20oC) 34.4 A5 Moderately persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier 2018: Dark aerobic conditions normalised Lab DT50 range 22.17-69.55 days, Soils=3
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value Stable A4 -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 19.6 A5 - @ 25 degC Non-persistent
Note pH sensitive: 24.1 days @ pH 5, 16.4 days @ pH 9, all at 25 degC
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for 24-epibrassinolide

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) - - -
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) - - -
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) > 5.0 A5 Danio rerio Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 2.86 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 10 A4 Apis mellifera, solubility limit Moderate
Oral acute 48 hour LD50 (μg bee-1) > 92.2 A5 Apis mellifera Moderate
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 0.69 >
A5 Aphidius rhopalosiphi
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 0.28 >
A5 Typhlodrumus pyri
-
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for 24-epibrassinolide

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class - - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 1.08 A5 Rat, 4 hr -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) None allocated A5 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) None allocated A5 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) None allocated A5 -
Dermal penetration studies (%) 0.01 A3 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public As the substance displays no biologically or toxicologically relevant hazard risks are consider negligible
Occupational As the substance displays no biologically or toxicologically relevant hazard risks are consider negligible
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Decrease in food consumption and loss of body weight may occur if ingested

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
CLP classification 2013 Environment: H413
EC Risk Classification Click here to view information omn the EU risk phrases -
EC Safety Classification Click here to view information omn the EU safety phrases -
WHO Classification - -
US EPA Classification (formulation) - -
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for 24-epibrassinolide

Language Name
English 24-epibrassinolide
French -
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian -
Polish -
Swedish -
Hungarian -
Dutch -

Record last updated: Thursday 04 April 2019
Contact: aeru@herts.ac.uk