Flamprop-M-isopropyl (Ref: WL 43425)
Last updated: 02/09/2023
(Also known as: flamprop-M; CL 901444; AC 901444; L-flamprop-isopropyl)
Flamprop-M-isopropyl is a discontinued herbicide. It has a low solubility in water, is volatile and there is some concern regarding risk of leaching to groundwater. It is moderately persistent in soils. Whilst it has a low mammalian toxicity there is some concern about bioaccumulation. No serious human health risks have been identified. It is moderately toxic to birds, most aquatic organisms, honeybees and earthworms.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A translocated, post-emergence arylalanine herbicide used to control wild-oats
Avena fatua
Wheat
-
Current
circa 1978
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Expired
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
Flamprop-M-isopropyl is the stereospecific ester of the L-isomer of flamprop.
C₁₉H₁₉ClFNO₃
CC(C)OC(=O)C(C)N(C1=CC(=C(C=C1)F)Cl)C(=O)C2=CC=CC=C2
C[C@@H](C(=O)OC(C)C)N(C1=CC(=C(C=C1)F)Cl)C(=O)C2=CC=CC=C2
IKVXBIIHQGXQRQ-CYBMUJFWSA-N
InChI=1S/C19H19ClFNO3/c1-12(2)25-19(24)13(3)22(15-9-10-17(21)16(20)11-15)18(23)14-7-5-4-6-8-14/h4-13H,1-3H3/t13-/m1/s1
Yes
Herbicide
Arylalanine herbicide
-
-
Synthetic
Selective, systemic, absorbed by leaves
63782-90-1
618-483-7
349
-
92366
No data found
363.81
isopropyl N-benzoyl-N-(3-chloro-4-fluorophenyl)-D-alaninate
isopropyl N-benzoyl-N-(3-chloro-4-fluorophenyl)-D-alaninate
1-methylethyl N-benzoyl-N-(3-chloro-4-fluorophenyl)-D-alaninate
-
-
Z
0
Not applicable
Not applicable
Avena fatua
White crystals
12
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
1560000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
147000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethanol
-
16000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Hexane
-
500000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Xylene
-
73.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
4.90 X 1003
Calculated
-
3.69
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
-
-
-
-
-
-
1.32
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
8.50 X 10-02
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
2.58 X 10-03
Non-volatile
-
-
-
-
-
-
-
55
S1 S = Expert judgement 1 = Estimated data with little or no verification
Moderately persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Best available data
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
W3 W = French database provided by ARVALIS-Institut du Végétal. Dataset no longer available. 3 = Unverified data of known source
Slightly mobile
750
Best available data
-
-
-
-
-
-
-
1.96
Calculated
Transition state
7.45 X 10-02
Calculated
-
-
Medium
Calculated
-
Slightly mobile
Calculated
-
120
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Threshold for concern
Not available
-
Known groundwater metabolites
None
None
Terrestrial ecotoxicology
> 4000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
-
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
2.5
-
-
-
-
> 2000
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Gallus domesticus
Low
-
-
-
-
-
-
1000
L1 L = Pesticide manuals and hard copy reference books / other sources 1 = Estimated data with little or no verification
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
40
L1 L = Pesticide manuals and hard copy reference books / other sources 1 = Estimated data with little or no verification
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 2.4
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 12
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Unknown species
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6.8
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Unknown species
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
> 4000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
List II
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
May cause skin damage if contact occurs
Not expected to autoignite; Not highly flammable
Health: H312 Environment: H400, H410
III (Slightly hazardous)
-
-
-
flamprop-M-isopropyl
flamprop isopropyl r-(-)-isomere
Flamprop-M-isopropyl
flamprop-M-isopropyl
flamprop-isopropile R
flamprop-M-isopropil
-
flamprop-M-izopropylu
-
-
-
-
Record last updated:
02/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242