The following Pesticide Hazard Tricolour (PHT) alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. The alerts for Highly Hazardous Pesticides (HHPs) are based on applying the FAO/WHO (Type 1) and the PAN (Type II) criteria to PPDB data. Further details on the HHP indicators are given in the tables below. Neither the PHT nor the HHP hazard alerts take account of usage patterns or exposure, thus they do not represent risk.
PHT: Environmental fate
PHT: Ecotoxicity
PHT: Human health
Highly Hazardous Pesticide
Environmental fate High alert: Persistent; Potential for particle bound transport: High
Fluindapyr is a pesticide active ingredient that has been shown to be highly effective in controlling a broad range of plant diseases on various crops and also for non-cropping situations
Example pests controlled
Asian Soybean rust; Scab; Brown rot blossom blight; Leaf rust; Pink snow mold; Powdery mildew
No UK approval for use as a plant protection agent
EC Regulation 1107/2009 (repealing 91/414)
EC Regulation 1107/2009 status
Pending
Dossier rapporteur/co-rapporteur
-
Date EC 1107/2009 inclusion expires
-
EU Candidate for substitution (CfS)
Not applicable
Listed in EU database
Yes
Approved for use (✓) under EC 1107/2009 in the following EU Member States
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
✓
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
Approved for use (✓) under EC 1107/2009 by Mutual Recognition of Authorisation and/or national regulations in the following EEA countries
ISIceland
NONorway
Additional information
Also used in
Paraguay
Chemical structure
Isomerism
Fluindapyr exhibits stereoisomerism due to the presence of a chiral carbon atom in its molecular structure, specifically within the 1-fluoroethyl group attached to the pyrazole ring. This chiral centre results in two enantiomers, (R)- and (S)-fluindapyr. The commercial formulation of fluindapyr is typically supplied as a racemic mixture.
R11 Rule 11: Pesticide active ingredients that are environmentally persistent (where sediment phase only DT₅₀ => 90 days or water phase only DT₅₀ => 90 days or DT₅₀ (field) => 60 days (note lab values are used when field values are not available))
]
Other status information
-
Herbicide Resistance Class (HRAC MoA class)
Not applicable
Herbicide Resistance Class (WSSA MoA class)
Not applicable
Insecticide Resistance Class (IRAC MoA class)
Not applicable
Fungicide Resistance Class (FRAC MOA class)
7
Examples of recorded resistance
-
Physical state
Off-white coloured solid
Commercial
Property
Value
Availability status
Novel
Introduction & key dates
2012, developed
Example manufacturers & suppliers of products using this active now or historically
Isagro S.p.A
FMC Corporation
Example products using this active
Adastrio
Kalida Fungicide SDS
Formulation and application details
Usually formulated as a suspension concentrate
Commercial production
Fluindapyr was produced through a modern, multi-step synthetic route typical of SDHI fungicides, but its commercial production still follows a clear, modular logic. Manufacturers first build the substituted pyrazole core, an established scaffold in contemporary fungicide chemistry, through condensation and cyclisation steps that introduce the key heterocycle with the correct substitution pattern. In parallel, they prepare the distinctive difluoromethyl-substituted aromatic fragment that defines fluindapyr’s potency and lipophilicity. These two intermediates are then coupled through a controlled acylation or related bond-forming step to assemble the full amide structure, with process conditions tuned to avoid decomposition of the sensitive difluoromethyl group. Final purification removes coloured or polymeric by-products common to heterocycle-aryl couplings, yielding technical grade fluindapyr that can be formulated.
As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below.
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242
Environmental fate
Ecotoxicity
Human health
Warning:
