Bixlozone is a herbicide used to control problematic grasses and broadleaved weeds in a wide range of crops. It is slightly soluble in water and is not highly volatile. Depending on local cobditions it can be moderately persistent in soils. It is hydrolytically stable. It is moderately toxic to birds. Bixlozone has a low oral mammalian toxicity.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate Moderate alert: Moderately persistent; GUS: Transition state; Drainflow: Moderately mobile; Potential for particle bound transport: Medium
Ecotoxicity Moderate alert: Birds acute ecotoxicity: Moderate; Fish acute ecotoxicity: Moderate; Fish chronic ecotoxicity: Moderate; Earthworms acute ecotoxicity: Moderate
Human health Low alert
GENERAL INFORMATION
Description
A herbicide used to control problematic grasses and broad-leaved weeds
Example manufacturers & suppliers of products using this active now or historically
FMC Australasia
Example products using this active
Overwatch
Isoflex
Formulation and application details
Usually formulated as a suspension concentrate
ENVIRONMENTAL FATE
Property
Value
Source; quality score; and other information
Interpretation
Solubility - In water at 20 °C (mg l⁻¹)
39.6
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Low
Solubility - In organic solvents at 20 °C (mg l⁻¹)
250000
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Acetone
-
120000
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Methanol
-
250000
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Ethy acetate
-
250000
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Toluene
-
Melting point (°C)
81.5
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
-
Boiling point (°C)
Decomposes before boiling
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
-
Degradation point (°C)
-
-
-
Flashpoint (°C)
-
-
-
Octanol-water partition coefficient at pH 7, 20 °C
P
2.00 X 1003
Calculated
-
Log P
3.3
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
High
Fat solubility of residues
Solubility
-
-
-
Data type
-
-
-
Density (g ml⁻¹)
1.37
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
-
Dissociation constant pKa) at 25 °C
-
-
-
-
Vapour pressure at 20 °C (mPa)
2.3 X 10-06
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Low volatility
Henry's law constant at 25 °C (Pa m³ mol⁻¹)
7.2 X 10-03
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Non-volatile
Maximum UV-vis absorption L mol⁻¹ cm⁻¹
-
-
-
Surface tension (mN m⁻¹)
66.5
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
-
Degradation
Property
Value
Source; quality score; and other information
Interpretation
General biodegradability
Not readily biodegradable
Soil degradation (days) (aerobic)
DT₅₀ (typical)
153
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Persistent
DT₅₀ (lab at 20 °C)
153
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Persistent
DT₅₀ (field)
93
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Not incorporated
Moderately persistent
DT₉₀ (lab at 20 °C)
-
-
-
DT₉₀ (field)
-
-
-
DT₅₀ modelling endpoint
-
-
-
Note
Australian 2019 dossier: Lab studies DT₅₀ range 64-330 days, Soils=7; Field studies (not incorporated) DT₅₀ range 46 to 267 days, Soils=7, Incorporated DT₅₀ = 31 to 446 days, Soils=7
Dissipation rate RL₅₀ on plant matrix
Value
-
-
-
Note
-
Dissipation rate RL₅₀ on and in plant matrix
Value
-
-
-
Note
-
Aqueous photolysis DT₅₀ (days) at pH 7
Value
49
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Stable
Note
-
Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7
Value
Stable
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Stable
Note
Stable at all relevant pH's
Water-sediment DT₅₀ (days)
-
-
-
Water phase only DT₅₀ (days)
-
-
-
Soil adsorption and mobility
Property
Value
Source; quality score; and other information
Interpretation
Linear
Kd
-
-
-
Koc
-
Notes and range
-
Freundlich
Kf
4.85
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Moderately mobile
Kfoc
400
1/n
0.84
Notes and range
Australian 2019 dossier Kf range 1.6-8.3 mL g⁻¹; Kfoc range 334-465 mL g⁻¹
pH sensitivity
-
Fate indices
Property
Value
Source; quality score; and other information
Interpretation
GUS leaching potential index
2.75
Calculated
Transition state
SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate
Value
2.30 X 10-01
Calculated
-
Note
-
Potential for particle bound transport index
Medium
Calculated
-
Potential for loss via drain flow
Moderately mobile
Calculated
-
Bio-concentration factor
BCF (l kg⁻¹)
-
-
-
CT₅₀ (days)
-
-
Other known metabolites
Metabolite name and reference
Aliases
Formation medium / Rate
Estimated maximum occurrence fraction
Metabolising enzymes
F9600-3-OH-propanamide
-
Soil
0.150
-
2,4-dichlorobenzoic acid
-
Soil
0.006
-
ECOTOXICOLOGY
Terrestrial ecotoxicology
Property
Value
Source; quality score; and other information
Interpretation
Mammals - Acute oral LD₅₀ (mg kg⁻¹)
> 2000
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Rat
Low
Mammals - Short term dietary NOEL
(mg kg⁻¹)
-
-
-
(ppm diet)
-
-
Mammals - Chronic 21d NOAEL (mg kg⁻¹ bw d⁻¹)
-
-
-
Birds - Acute LD₅₀ (mg kg⁻¹)
> 887
M4 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 4 = Verified data
Taeniopygia guttata
Moderate
Birds - Short term dietary (LC₅₀/LD₅₀)
-
-
-
Birds - Chronic 21d NOEL (mg kg⁻¹ bw d⁻¹)
-
-
-
Earthworms - Acute 14 day LC₅₀ (mg kg⁻¹)
607
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Moderate
Earthworms - Chronic NOEC, reproduction (mg kg⁻¹)
-
-
-
Soil micro-organisms
-
-
-
Collembola
Acute LC₅₀ (mg kg⁻¹)
-
-
-
Chronic NOEC (mg kg⁻¹)
-
-
-
Non-target plants
-
-
-
-
-
-
Honeybees (Apis spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 100
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Apis mellifera
Low
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 100
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Apis mellifera
Low
Unknown mode acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Chronic
-
-
-
Bumblebees (Bombus spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
-
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
-
Mason bees (Osmia spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Other pollinators (1)
Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)
-
-
-
Mode of exposure
-
Other pollinators (2)
Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)
-
-
-
Mode of exposure
-
Beneficial insects (Ladybirds)
-
-
-
Beneficial insects (Lacewings)
-
-
-
Beneficial insects (Parasitic wasps)
-
-
-
Beneficial insects (Predatory mites)
-
-
-
Beneficial insects (Ground beetles)
-
-
-
Aquatic ecotoxicology
Property
Value
Source; quality score; and other information
Interpretation
Fish - Acute 96 hour LC₅₀ (mg l⁻¹)
9.8
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Oncorhynchus mykiss
Moderate
Fish - Chronic 21 day NOEC (mg l⁻¹)
0.38
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Aquatic plants - Acute 7 day EC₅₀, biomass (mg l⁻¹)
-
-
-
Algae - Acute 72 hour EC₅₀, growth (mg l⁻¹)
-
-
-
Algae - Chronic 96 hour NOEC, growth (mg l⁻¹)
-
-
-
Mesocosm study data
NOEAEC mg l⁻¹
-
-
-
NOEAEC mg l⁻¹
-
-
-
HUMAN HEALTH AND PROTECTION
General
Property
Value
Source; quality score; and other information
Interpretation
Threshold of Toxicological Concern (Cramer Class)
-
-
-
Mammals - Acute oral LD₅₀ (mg kg⁻¹)
> 2000
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
Rat
Low
Mammals - Dermal LD₅₀ (mg kg⁻¹ body weight)
-
-
-
Mammals - Inhalation LC₅₀ (mg l⁻¹)
-
-
-
Other Mammal toxicity endpoints
-
-
-
ADI - Acceptable Daily Intake (mg kg⁻¹ bw day⁻¹)
0.3
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
M5 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems) (click here ) 5 = Verified data used for regulatory purposes
-
Health issues
Specific human health issues
Carcinogen
Genotoxic
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
;
B0 B = DNA damage/repair (EFSA database) 0 = No data
;
C0 C = Gene mutation (EFSA database) 0 = No data
;
D0 D = Genome mutation (EFSA database) 0 = No data
;
E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
?Possibly, status not identified
XNo, known not to cause a problem
Eye irritant
Phototoxicant
 
?Possibly, status not identified
XNo, known not to cause a problem
 
General human health issues
No information available
Handling issues
Property
Value and interpretation
General
Not highly flammable; Not expected to autoignite Not oxidising or explosive
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242