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fuberidazole
** furidazol ** furidazole ** fuberidazole (MBC) ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for fuberidazole

Description: A fungicide used mainly as a seed treatment to control a variety of soil and seed borne diseases in cereals

Example pests controlled: Fusarium spp.; Snow mould; Stinking smut

Example applications: Cereals

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1970

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur UK/Finland
Date inclusion expires Expired
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C11H8N2O
Canonical SMILES C1=CC=C2C(=C1)NC(=N2)C3=CC=CO3
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) UYJUZNLFJAWNEZ-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide, Seed treatment
Substance group Benzimidazole
Minimum active substance purity 970 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Systemic with specific action against Fusarium spp. Inhibition of mitosis and cell division (Beta-tubulin assembly in mitosis).
CAS RN 3878-19-1
EC number 223-404-0
CIPAC number 525
US EPA chemical code -
PubChem CID 19756
Molecular mass (g mol-1) 184.19
PIN (Preferred Identification Name) -
IUPAC name 2-(2'-furyl)benzimidazole
CAS name 2-(2-furanyl)-1H-benzimidazole
Other status information PAN listed Highly Hazardous Chemical
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 1
Examples of recorded resistance -
Physical state Light brown to colourless crystalline powder
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Makhteshim-Agan
  • Bayer
Example products using this active
  • Tripod Plus
  • Baytan FS
  • Voronit
UK LERAP status None
Formulation and application details Usually supplied as a flowable concentrate for use as a seed dressing.


ENVIRONMENTAL FATE

for fuberidazole

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 71 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 350 A5 - Toluene -
14000 A5 - Acetone -
7900 A5 - Ethyl acetate -
6600 A5 - Dichloromethane -
Melting point (oC) Decomposes on melting A5 -
Boiling point (oC) Decomposes before boiling L3 -
Degradation point (oC) 292 L3 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 5.13 X 1002 Calculated -
Log P 2.71 A5 Moderate
Bulk density (g ml-1)/Specific gravity 1.246 A5 -
Dissociation constant (pKa) at 25oC 4 A4 -
Note: Weak base
Vapour pressure at 20oC (mPa) 9.00 X 10-04 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.00 X 10-06 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.69 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 4.64 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 298.7nm = 26651, 306.3nm = 33982, 321.5nm = 26243 A5 -
Surface tension (mN m-1) 72.35 A5 at 20oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 6 L3 Non-persistent
DT50 (lab at 20oC) 24.6 A5 Non-persistent
DT50 (field) 6 L3 Non-persistent
DT90 (lab at 20oC) 88.7 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 6.3-56.5 days, DT90 range 20.8-187.7 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 0.15 A4 Fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 4 to pH 9
Water-sediment DT50 (days) 15.1 A5 Fast
Water phase only DT50 (days) 0.59 A5 Fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 9.84 A5 Slightly mobile
Kfoc 605
1/n 0.82
Notes and range EU dossier Kf range 6.24-16.89 mL/g, Kfoc range 420-698 mL/g, 1/n range 0.750-0.866, Soils=4
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
1H-benzimidazole-2-carboxylic acid This metabolite may cause environmental pollution, click here for further information Soil   0.147   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
(2E)-4-(1H-benzimidazol-2-yl)-4-oxobut-2-enoic acid trans-oxobutenoic acid; fuberidazole metabolite M17 Water (Photolysis) - -
1H-benzimidazole-2-carboxylic acid fuberidazole metabolite M01 Soil - -
4-(1H-benzimidazol-2-yl)-4-hydroxybutanoic acid fuberidazole metabolite M09 Plant - -
hydroxyfuberidazole glucoside - Rate (Bile) - -
1-(1H-benzimidazole-2-yl)ethanone
Note: Possible groundwater contaiminant
fuberidazole metabolite M11 Soil - -
4-(1H-benzimidazol-2-yl)-4-oxobutanal oxobutanal benzimidazole; fuberidazole metabolite M15 Soil (Photolysis) - -
(2Z)-4-(1H-benzimidazol-2-yl)-4-oxobut-2-enoic acid cis-oxobutenoic acid; fuberidazole metabolite M16 Water (Photolysis) - -


ECOTOXICOLOGY

for fuberidazole

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 37 Q2 Estimated Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 300 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) > 20 L2 Rat, 2 year High
(ppm diet) > 80 -
Birds - Acute LD50 (mg kg-1) > 750 A5 Coturnix japonica Moderate
Birds - Short term dietary (LC50/LD50) > 930 mg kg bw-1 day-1 A5 Coturnix japonica -
Fish - Acute 96 hour LC50 (mg l-1) 0.91 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 4.7 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.12 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 1.4 A5 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) 0.5 Q2 Unknown species Moderate
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 200 A5 Low
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 187.2 A5 Low
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) > 500 A5 Eisenia foetida, corr Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect 260.6 A5 Folsomia candida, NOEC -
Other arthropod (1) LR50 g ha-1 - - -
% Effect 0 Mortality
Dose: 26 g ha-1
A5 Aphidius rhopalosiphi
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 8.9 Mortality
Dose: 26 g ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 0.07 g/kg soil
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for fuberidazole

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 300 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 0.458 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0072 A5 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.08 A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.0072 A5 -
Dermal penetration studies (%) 1.0-6.0 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public Negligible risk of exposure considering patterns of use
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B3; C3; D0; E0

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Moderately toxic
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H302, H317, H351, H373
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S22, S60, S61
WHO Classification II - Moderately hazardous
UN Number Usually 2588
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for fuberidazole

Language Name
English fuberidazole
French fuberidazole
German Fuberidazol
Danish fuberidazole
Italian fuberidazolo
Spanish fuberidazol
Greek fuberidazole
Slovenian fuberidazol
Polish fuberidazol
Swedish fuberidazol
Hungarian fuberidazol
Dutch fuberidazool

Record last updated: Tuesday 25 June 2019
Contact: aeru@herts.ac.uk