Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

imazosulfuron (Ref: TH 913)
** URA-09800-H-0-WG ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for imazosulfuron

Description: A herbicide used to control most annual and perennial broad-leaved weeds in rice and some other crops

Example pests controlled: Sedges including yellow nutsedge, Hemp sesbania, Broad-leaved weeds

Example applications: Turf; Rice; Tomatoes; Peppers; Cereals including wheat, barley, rye and triticale

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1994

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Slovenia/Finland
Date inclusion expires Not applicable
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C14H13ClN6O5S
Canonical SMILES COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)C2=C(N=C3N2C=CC=C3)Cl)OC
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) NAGRVUXEKKZNHT-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H13ClN6O5S/c1-25-9-7-10(26-2)18-13(17-9)19-14(22)20-27(23,24)12-11(15)16-8-5-3-4-6-21(8)12/h3-7H,1-2H3,(H2,17,18,19,20,22)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Sulfonylurea
Minimum active substance purity >93%, 980 g/kg
Known relevant impurities EC RAR 2016: None declared
Substance origin Synthetic
Mode of action Inhibits plant growth, absorbed through roots and translocated throughout plant. Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS
CAS RN 122548-33-8
EC number 602-788-7
CIPAC number 590
US EPA chemical code 118602
PubChem CID 92433
Molecular mass (g mol-1) 412.83
PIN (Preferred Identification Name) -
IUPAC name 1-(2-chloroimidazo[1,2-a]pyridin-3-ylsulfonyl)-3-(4,6-dimethoxypyrimidin-2-yl)urea
CAS name 2-chloro-N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]imidazo[1,2-a]pyridine-3-sulfonamide
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) B
Herbicide Resistance Classification (WSSA) 2
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Lindernia dubia
Physical state Whte crystalline powder
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Sumitomo Chemical Co. Ltd.
Example products using this active
  • Takeoff
  • League
  • Imazosulfuron 50 WG
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Available as water dispersible granules or as a suspension concentrate.


ENVIRONMENTAL FATE

for imazosulfuron

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 429.0 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 2200 L3 - Ethyl acetate -
4479 A5 - Acetone -
400 L3 - Xylene -
12745 A5 - Dichloromethane -
Melting point (oC) 183.5 L3 -
Boiling point (oC) 198 A5 -
Degradation point (oC) 195 A3 -
Flashpoint (oC) Not expected to self-ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 8.51 X 10-01 Calculated -
Log P -0.07 A5 Low
Bulk density (g ml-1)/Specific gravity 1.53 A5 -
Dissociation constant (pKa) at 25oC 0.30 A5 -
Note: pKa(II)=3.94; Strong acid
Vapour pressure at 20oC (mPa) 3.5 X 10-03 A4 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) - - -
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.49 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 3.96 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 57.31 A5 Moderately persistent
DT50 (lab at 20oC) 57.31 A5 Moderately persistent
DT50 (field) 56 A5 Moderately persistent
DT90 (lab at 20oC) 600 A3 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Lab studies DT50 range 21-75 days, field study range 21-91 days (Germany)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 3.1 A5 Moderately fast
Note pH 4 DT50=8.5 days
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note pH 4: DT50 7.0 days; Stable at pH 9 DT50 > 1 year
Water-sediment DT50 (days) 120 A5 Slow
Water phase only DT50 (days) 257 A5 Stable

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - A4 -
Koc -
Notes and range -
Freundlich Kf 3.36 A5 Slightly mobile
Kfoc 1415
1/n 0.93
Notes and range EU dossier Kf range 0.76-4.49 mL/g, Kfoc range 76-4490 mL/g, 1/n range 0.86-1.02, Soils=5; RAR 2016 Kfoc 135-428 mL/g, 1/n 0.78-0.89, Soils=5
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
1-(2-chloroimidazol(1,2-a)pyridine-3-yl-sulfonyl)-3-(4-hydroxy-6-methoxypyrimidin-2-yl)urea This metabolite may cause environmental pollution, click here for further information Soil   0.127   Major fraction; Relevant
2-chloroimidazol(1,2-a)pyridine-3-sulfonamide This metabolite may cause environmental pollution, click here for further information Soil   0.258   Major fraction; Relevant
N-(((amino(imino)methyl)amino)carbonyl)-2-chloroimidazo(1,2-a)pyridine-3-sulfonamide Soil (anaerobic)   0.056   Minor fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2-amino-4,6-dimethoxypyrimidine ADPM Rat; Water; Soil - -
2-amino-4-hydroxy-6-methoxypyrimidine AHMP Soil (anaerobic) 0.056 -
2-cyano-4,6-dimethoxypyrimidne CDPM Water (photolysis) - -
1(2-chloroimidazol(1,2-a)pyridine-3-yl-sulfonyl)-3-(4-hydroxy-5,6-dimethoxypyrimidine-2-yl)urea HDS Rat - -
1(2-chloroimidazol(1,2-a)pyridine-3-yl-sulfonyl)-3-(5-hydroxy-4,6-dimethoxypyrimidine-2-yl)urea IHDU Rat - -
2-(2-imino-1,2-dihydropyridin-1-yl)oxalic acid IHOA Water (photolysis) - -
(4,6-dimethoxypyridine-2-yl)aminocarbonylsulfamic acid SDPM Soil (anaerobic); Water (photoylsis) - -
4,6-dimethoxy-2-ureidopyrimidine UDPM Rat; Soil (photolysis), Water (photolysis) - -


ECOTOXICOLOGY

for imazosulfuron

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) 106 L2 Rat, 2 year Moderate
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 2250 A5 Anas platyrhynchos Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) > 100 A5 Oncorhynchus mykiss Low
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 91 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 1.2 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.00075 A5 Lemna gibba High
Non-target plants > 500 A5 Avena sativa
Seedling emergence, ER50
as g/ha
-
> 50 A5 Avena sativa
Vegetative vigour, ER50
as g/ha
-
Algae - Acute 72 hour EC50, growth (mg l-1) 0.69 A5 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 100 A5 Low
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 41.6 A5 Moderate
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 500 A5 Eisenia foetida Low
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 50 >
A5 Typhlodromus pyri
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 50 >
A5 Aphidius rhopalosiphi
-
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 25 mg kg-1 soil, 56 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for imazosulfuron

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 2.12 A5 Rat (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.75 A5 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.53 A5 -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 [Low risk when used as prescribed] - -
Exposure Routes Public Negligible risk when used as prescribed
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A0; B0; C0; D0; E3

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

General human health issues Possible liver & thyroid toxicant
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
CLP classification 2013 Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases N - Dangerous for the environment: R52/53
EC Safety Classification Click here to view information omn the EU safety phrases None allocated at this time
WHO Classification NL - Not listed
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for imazosulfuron

Language Name
English imazosulfuron
French imazosulfuron
German Imazosulfuron
Danish imazosulfuron
Italian imazosulfuron
Spanish imazosulfuron
Greek -
Slovenian imazosulfuron
Polish imazosulfuron
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 23 May 2018
Contact: aeru@herts.ac.uk