Isoprothiolane (Ref: SS 11946)
Last updated: 01/09/2023
(Also known as: IPT; NNF 109)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An insecticide and fungicide used to control a range of rice pests
Rice stem rot, Fusarium leaf spot, Planthoppers
Rice
-
Considered obsolete but may be available in some countries
1975, first reported and introduced
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
-
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
None
C₁₂H₁₈O₄S₂
CC(C)OC(=O)C(=C1SCCS1)C(=O)OC(C)C
No data
UFHLMYOGRXOCSL-UHFFFAOYSA-N
InChI=1S/C12H18O4S2/c1-7(2)15-10(13)9(11(14)16-8(3)4)12-17-5-6-18-12/h7-8H,5-6H2,1-4H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
isoprothiolane
-
Fungicide, Insecticide
Phosphorothiolate insecticide; Phosphorothiolate fungicide; Dithiolane fungicide
-
-
Synthetic
Systemic with protective and curative action. Phospholipid biosynthesis inhibitor.
50512-35-1
610-537-8
456
-
39681
No data found
290.40
-
diisopropyl 1,3-dithiolan-2-ylidenemalonate
bis(1-methylethyl) 1,3-dithiolan-2-ylidenepropanedioate
-
-
Not applicable
Not applicable
Not applicable
6
-
Colourless crystals
King Tech Corp. Nihon Nohyaku Co. Ltd.
Fudiolan Fuji-One Fujiwang Vifusi
Available in a variety of formulations including emulsifiable concentrates, granules, wettable powders and low and ultralow volume sprays.
54
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderate
1512000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
-
761000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethanol
-
4061000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
10000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
n-Hexane
-
54.9
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
2.00 X 1003
Calculated
-
3.3
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
-
-
-
-
-
-
1.04
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
18.8
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Highly volatile
1.00 X 10-01
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately volatile
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
Slightly mobile
1352
Estimated
-
-
-
-
-
-
-
-
-
-
Cannot be calculated
-
-
-
-
-
-
-
-
-
354
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Threshold for concern
Not available
-
None
Terrestrial ecotoxicology
1190
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
-
-
-
-
-
-
-
-
> 4180
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Coturnix japonica
Low
-
-
-
-
-
-
> 91.95
R4 R = Peer reviewed scientific publications 4 = Verified data
Eisenia foetida
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6.8
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
62
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4.58
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Pseudokirchneriella subcapitata
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
1190
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
10250
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
2.7
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
No further information available
No information available
Health: H302
II (Moderately hazardous)
-
-
-
isoprothiolane
isoprothiolane
Isoprothiolan
isoprothiolan
isoprothiolane
isoprotiolan
-
izoprotiolan
-
-
-
-
Record last updated:
01/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242