Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

meptyldinocap (Ref: DE 126)
** GF-1478 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Meptyldinocap is a protectant, curative and eradicant fungicide approved for use in the EU. It has a low aqueous solubility, it is volatile and, based on its chemical propoerties, is unlikely to leach to groundwater. It is not persistent in soil and will usually degrade in water systems quickly. It is modertaely toxic to mammals and bioaccumlation may be a concern. Whilst it is not highly to toxic to birds is is toxic to many aquatic species including fish and algae.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for meptyldinocap

Description: A dinitrophenol fungicide that is a single isomer of dinocap and active against powdery mildew mainly on fruit and other crops

Example pests controlled: Powdery mildew

Example applications: Vines; Curcubits; Fruit including apples, pears, peaches, plums, straberries, grapes,

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 2007

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires 31/03/2025
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Chile; Africa; India

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism The single isomer of the existing active substance dinocap
Chemical formula C18H24N2O6
Canonical SMILES CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]
Isomeric SMILES CCCCCCC(C)C1=CC(=CC(=C1OC(=O)/C=C/C)[N+](=O)[O-])[N+](=O)[O-]
International Chemical Identifier key (InChIKey) NIOPZPCMRQGZCE-WEVVVXLNSA-N
International Chemical Identifier (InChI) InChI=1S/C18H24N2O6/c1-3-5-6-7-8-9-11-14-12-15(19(22)23)13-16(20(24)25)18(14)26-17(21)10-4-2/h4,10,12-13H,3,5-9,11H2,1-2H3/b10-4+
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide
Substance group Dinitrophenol
Minimum active substance purity 900 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Protectant, curative and eradicant activity by inhibiting spore germination. Uncoupler of oxidative phosphorylation
CAS RN 131-72-6
Alternative/old CAS RN 6119-92-2
EC number 228-088-8
CIPAC number 811
US EPA chemical code 036000
PubChem CID 5284389
Molecular mass (g mol-1) 364.39
PIN (Preferred Identification Name) -
IUPAC name (RS)-2-(1-methylheptyl)-4,6-dinitrophenyl crotonate
CAS name 2-(1-methylheptyl)-4,6-dinitrophenyl (2E)-2-butenoate
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 29
Examples of recorded resistance -
Physical state Yellowish brown liquid
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Dow AgroSciences
  • Landseer
Example products using this active
  • Kindred
  • karathane
  • GF-1478
UK LERAP status None
Formulation and application details Usually supplied as an emulsifiable concentrate that is mixed with water and used as a spray.


ENVIRONMENTAL FATE

for meptyldinocap

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.248 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 252000 A5 - Acetone -
256000 A5 - Ethyl acetate -
251000 A5 - n-Heptane -
256000 A5 - Xylene -
Melting point (oC) -22.5 A5 - Freezing point -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 200 A5 -
Flashpoint (oC) 30 A5 -
Octanol-water partition coefficient at pH 7, 20oC P 3.55 X 1006 Calculated -
Log P 6.55 A5 High
Bulk density (g ml-1)/Specific gravity 1.11 R4 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 0.00792 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.16 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -2.14 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 Neutral & Acidic solution: 240nm = 16727, 310nm = 2155; [Basic solution: 260nm = 6575, 372nm = 12980, 405nm = 10969 A5 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 12.0 A5 Non-persistent
DT50 (lab at 20oC) 12.0 A5 Non-persistent
DT50 (field) 15 R4 Non-persistent
DT90 (lab at 20oC) 64.7 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 4.1-22.4 days, DT90 range 13.7-122 days; Manufacturers published lab studies range 4-24 days (E3)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value 2.8 R3 -
Note Mango fruit, n=1
Aqueous photolysis DT50 (days) at pH 7 Value 0.4 A5 Fast
Note Natural light 40 deg N
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 43 A5 Moderately persistent
Note pH sensitive: 447 days @ pH4, 229 days @ pH5, 56 and 30.4 days @ pH7, 0.7 and 9.3 days @ pH9, all at 20 deg C
Water-sediment DT50 (days) 3.54 A5 Fast
Water phase only DT50 (days) 5.7 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 705 A4 Non-mobile
Kfoc 958245
1/n 1.05
Notes and range EU dossier Kf range 52-3102mL/g, Kfoc range 2889-310200 mL/g, 1/n range 0.9-1.73, Soils=6; EU dossier and Manufacturers published data gives Kfoc/Koc range 2889-310200 mL/g
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
2,4-dinitro-6-octylphenol This metabolite may cause environmental pollution, click here for further information Soil   0.22   Major fraction, Relevant
dinocap (Ref: ENT 24727) This metabolite may cause environmental pollution, click here for further information Soil   0.832   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2,4-dinitro-6-(1-methyl-beta-hydroxypentanoate)phenol - Rat (Urinary) - -
2,4-dinitro-6-(1-methyl-alpha,beta-pentanoate)phenol - Rat (Urinary) - -
2,4-diacetaminonitro-6-(1-methylpentanoate)phenol - Rat (Urinary) - -
2-acetoamino-4-nitro-6-(1-methyl-alpha,beta-pentenoate)phenol - Rat (Urinary) - -
2,4-dinitro-6-(1-methylpentanoate)phenol - Rat (Urinary) - -
2,4-dinitro-6-(1-methylbutanoate)phenol - Rat (Urinary) - -


ECOTOXICOLOGY

for meptyldinocap

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 992 A5 Whole fish Threshold for concern
CT50 (days) 0.6 -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 2150 A4 Colinus virginianus, for dinocap Low
Birds - Short term dietary (LC50/LD50) 344 mg kg bw-1 day-1 A4 Colinus virginianus, as dinocap -
Fish - Acute 96 hour LC50 (mg l-1) 0.0569 A5 Lepomis macrochirus High
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0041 A4 Daphnia pulicaria High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 2.12 A5 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 84.8 A5 Moderate
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 90 A5 Moderate
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) 302 A5 Eisenia foetida, corr Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 10.91 A5 Typhlodromus pyri -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect 16.7
28.8
Mortality
Parasitism
Dose: 0.84 kg ha-1
R4 Aphidius rhopalosiphi
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 0.62 mg kg-1 soil
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for meptyldinocap

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 1.24 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.016 A3 proposed Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.12 A3 proposed Rabbit, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.008 A3 proposed Dog, SF=200 -
Dermal penetration studies (%) 1.0-10.0 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Acceptable risks for proposed uses
Occupational Acceptable risks for proposed uses
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Possible liver and thyroid toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Flammable
Not explosive or oxidising
IMDG Transport Code is usually 3
CLP classification 2013 Health: H302, H317, H319, H332, H336
Handling: H226
Environment: h400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R43
H - Handling risks: R10
N - Dangerous for the environment: R50/53
EC Safety Classification Click here to view information omn the EU safety phrases S24, S37, S60, S61
WHO Classification NL - Not listed
US EPA Classification (formulation) - -
UN Number Usually 1993
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for meptyldinocap

Language Name
English meptyldinocap
French meptyldinocap
German Meptyldinocap
Danish meptyldinocap
Italian meptyldinocap
Spanish meptildinocap
Greek -
Slovenian meptildinokap
Polish meptyldinokap
Swedish -
Hungarian -
Dutch -

Record last updated: Thursday 13 September 2018
Contact: aeru@herts.ac.uk