Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!
methidathion (Ref: ENT 27193 )
** OMS 844 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for methidathion

Description: An insecticide and acaricide used to control a wide range of chewing and sucking pests

Example pests controlled: Scales; Spider mites; Bollworm; Budworm; Lygus bugs; Whitefly

Example applications: Sunflower; Artichokes; Apples; Almonds; Cherries; Citrus; Sorghum; Cotton; Alfalfa

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1968

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Portugal
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C6H11N2O4PS3
Canonical SMILES COC1=NN(C(=O)S1)CSP(=S)(OC)OC
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) MEBQXILRKZHVCX-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C6H11N2O4PS3/c1-10-5-7-8(6(9)16-5)4-15-13(14,11-2)12-3/h4H2,1-3H3
2D structure diagram/image available? Yes

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Common Name Relationship Link
Methidathion - Click here for the CCDC structure diagram

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide
Substance group Organophosphate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Non-systemic with contact and stomach action. Cholinesterase inhibitor.
CAS RN 950-37-8
EC number 213-449-4
CIPAC number 193
US EPA chemical code 100301
PubChem CID 13709
Molecular mass (g mol-1) 302.3
PIN (Preferred Identification Name) -
IUPAC name 3-dimethoxyphosphinothioylthiomethyl-5-methoxy-1,3,4-thiadiazol-2(3H)-one
CAS name S-((5-methoxy-2-oxo-1,3,4-thiadiazol-3(2H)-yl)methyl) O,O-dimethyl phosphorodithioate
Other status information Marine Pollutant; Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Aedes nigromaculis
Aphis gossypii
Bemisia tabaci
Meligethes aeneus
Myzus persicae
Plutella xylostella
many more
Physical state Colourless crystals
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • King Tech Corp
  • Makhteshim Agan
  • Syngenta
  • Ciba Geigy
Example products using this active
  • Cobra
  • Cobracide
  • Suprathion
  • Supracide
  • Ultracid
  • Ultracide
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as an emulsifiable concentrate or wettable powder.


ENVIRONMENTAL FATE

for methidathion

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 240 K4 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 150000 L3 - Ethanol -
670000 L3 - Acetone -
11000 L3 - Hexane -
14000 L3 - n-Octanol -
Melting point (oC) 39.5 L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 3.72 X 1002 Calculated -
Log P 2.57 K4 Low
Bulk density (g ml-1)/Specific gravity 1.51 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 0.25 L3 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 3.30 X 10-04 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.18 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 9.23 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 10 L3 Non-persistent
DT50 (lab at 20oC) 10 L3 Non-persistent
DT50 (field) 7 X3 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Lab and field studies DT50 range 3-18 days
Dissipation rate RL50 on plant matrix Value 5.0 R4 -
Note Published literature RL50 range 0.45-11.36 days, 6 field & undercover grown crops, various matrices, n=7
Dissipation rate RL50 on and in plant matrix Value 6.5 R4 -
Note Published literature RL50 range 1.5-12.6 days, 3 field & undercover grown crops, various matrices, n=5; Grapes in cold storage RL50=64 days.
Aqueous photolysis DT50 (days) at pH 7 Value 14 Q3 Slow
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 27 K4 Non-persistent
Note -
Water-sediment DT50 (days) 70 K4 Moderately fast
Water phase only DT50 (days) 6 K4 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - G3 Moderately mobile
Koc 400
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for methidathion

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 12.6 R3 Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 25 F4 Rat High
Mammals - Short term dietary NOEL (mg kg-1) 0.2 L2 Rat, 2 year High
(ppm diet) 4 -
Birds - Acute LD50 (mg kg-1) 23.6 L3 Anas platyrhynchos High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.01 L3 Oncorhynchus mykiss High
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0064 J4 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) > 22 L3 Scenedemus subspicatus Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) > 0.2 P3 Chlorella pyrenoidosa Moderate
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 0.13 K4 High
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) 5.6 L3 Eisenia foetida High
Earthworms - Chronic NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms Acute LC50 (mg kg-1) - - -
Chronic NOEC (mg kg-1) - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Harmful AA2 Typhlodromus pyri -
Other arthropod (2) LR50 g ha-1 - - -
% Effect Harmful AA2 Chrysoperla carnea -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for methidathion

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 25 F4 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 200 L3 Rabbit -
Mammals - Inhalation LC50 (mg l-1) 0.14 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.001 JMPR 1997 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.01 UK ACP 1999 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Routes Public -
Occupational May be absorbed through the skin
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B0; C0; D0; E3

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Possible nervous system, liver, gall bladder and ovaries toxicant
USEPA - possible human carcinogen
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes IMDG Transport Code is 6.1
CLP classification 2013 Health: H300, H302
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Very toxic: R28
Xn - Harmful: R21
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S22, S28, S36/37, S45, S60, S61
WHO Classification Ib - Highly hazardous
UN Number 2783
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for methidathion

Language Name
English methidathion
French methidathion
German Methidathion
Danish methidathion
Italian metidation
Spanish metidation
Greek methidathion
Slovenian metidation
Polish metydation
Swedish -
Hungarian -
Dutch methidathion

Record last updated: Wednesday 27 November 2019
Contact: aeru@herts.ac.uk