Ofurace (Ref: AE F057623)
Last updated: 18/01/2023
(Also known as: RE 20615; milfuram; RE 20615; HOE 057623)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A fungicide used to control a range of diseases but mainly downy mildew and late blights
Late blight; Downy mildew; Damping-off; Seed rot; Root rot
Fruit including grapes; Potatoes; Tobacco; Safflowers; Tomatoes
-
-
1992
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
A chiral molecule. The technical material is a racemate comprising equal amounts of (R)- and (S)-ofurace.
C₁₄H₁₆ClNO₃
CC1=C(C(=CC=C1)C)N(C2CCOC2=O)C(=O)CCl
No data
OWDLFBLNMPCXSD-UHFFFAOYSA-N
InChI=1S/C14H16ClNO3/c1-9-4-3-5-10(2)13(9)16(12(17)8-15)11-6-7-19-14(11)18/h3-5,11H,6-8H2,1-2H3
Yes
Fungicide
Phenylamide fungicide; Anilide fungicide
-
-
Synthetic
Systemic with curative and protective action. Disrupts fungal nucleic acid synthesis - RNA ploymerase 1.
58810-48-3
261-451-9
444
-
42850
No data found
281.74
-
(RS)-α-(2-chloro-N-2,6-xylylacetamido)-γ-butyrolactone
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furanyl)acetamide
-
-
Not applicable
Not applicable
Not applicable
4
-
Colourless crystals
Usually formulated as a suspension concentrate or wettable powder
146
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderate
68000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
27000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethyl acetate
-
27000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
-
8600
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
p-Xylene
-
145
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
2.45 X 1001
Calculated
-
1.39
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
-
-
-
-
-
-
1.43
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
2.00 X 10-02
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
3.90 X 10-05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
26
W4 W = French database provided by ARVALIS-Institut du Végétal. Dataset no longer available. 4 = Verified data
Non-persistent
-
-
-
26
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately fast
-
0.3
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
Mobile
38
Estimated
-
-
-
-
-
-
-
3.42
Calculated
High leachability
4.15 X 10-01
Calculated
-
-
Low
Calculated
-
Mobile
Calculated
-
Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
-
-
None
Terrestrial ecotoxicology
2600
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
2.5
L1 L = Pesticide manuals and hard copy reference books / other sources 1 = Estimated data with little or no verification
Rat
High
-
-
-
-
-
> 5000
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Phasianidae
Low
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
58
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Apis mellifera
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 29
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 46
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
2600
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Low
5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rabbit
-
2.06
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
0.03
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
No data found
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
XNo, known not to cause a problem
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
No further information available
No information available
Health: H319
III (Slightly hazardous)
-
-
ofurace
ofurace
Ofurace
ofurace
ofurace
ofurace
-
ofuras
-
-
-
-
Record last updated:
18/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242