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parathion-methyl (Ref: OMS 213)
** metaphos ** meptox ** thiophenit ** quinophos ** methyl-parathion ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for parathion-methyl

Description: An insecticide used to control sucking and chewing insects in a wide range of crops

Example pests controlled: Aphids; Boll weevils; Mealybugs; Scale; Armyworms

Example applications: Cereals; Cotton; Vegetables; Soybean; Fruit; Vines

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1950

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Italy
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA, Costa Rica

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C8H10NO5PS
Canonical SMILES COP(=S)(OC)OC1=CC=C(C=C1)[N+](=O)[O-]
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) RLBIQVVOMOPOHC-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3
2D structure diagram/image available? Yes

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Common Name Relationship Link
Parathion-methyl - Click here for the CCDC structure diagram

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide
Substance group Organophosphate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Contact and stomach insecticide. Cholinesterase inhibitor.
CAS RN 298-00-0
EC number 206-050-1
CIPAC number 487
US EPA chemical code 053501
PubChem CID 4130
Molecular mass (g mol-1) 263.21
PIN (Preferred Identification Name) -
IUPAC name O,O-dimethyl O-4-nitrophenyl phosphorothioate
CAS name O,O-dimethyl O-(4-nitrophenyl) phosphorothioate
Other status information Chemical subject to PIC regulations; Potential groundwater contaminant; Marine Pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Aedes melanimon
Aedes nigromaculis
Anopheles albimanus
Coleomegilla maculata
Culex pipiens pallens
many others
Physical state Colourless crystals
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • FCC Ltd
  • Cheminova A/S
  • Monsanto
Example products using this active
  • Sweeper
  • Amithion
  • Prompt
  • Sabidol
  • Wolfatox
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Available in a wide variety of formulations including dustable powders, emulsifible concentrates, encapsulated suspensions, ULV liquid and wettable powders.


ENVIRONMENTAL FATE

for parathion-methyl

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 55 L3 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 200000 L3 - Dichloromethane -
200000 L3 - Toluene -
15000 L2 - Hexane -
Melting point (oC) 35.5 L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) 150 L3 -
Octanol-water partition coefficient at pH 7, 20oC P 1.00 X 1003 Calculated -
Log P 3 L3 Moderate
Bulk density (g ml-1)/Specific gravity 1.36 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 0.2 L3 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 8.57 X 10-03 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.46 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 2.54 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 12 Y4 Non-persistent
DT50 (lab at 20oC) 12 Y4 Non-persistent
DT50 (field) 10 Y4 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note PIC DGD states lab DT50 range 1-18 days
Dissipation rate RL50 on plant matrix Value 3.6 R4 -
Note Published literature RL50 range 0.4-6.7 days, 6 field crops, various matrices, n=8
Dissipation rate RL50 on and in plant matrix Value 1.9 R4 -
Note Published literature RL50 range 0.7-6.6 days, 7 field crops, various matrices, n=12; Fruit in cold storage RL50 range 63-65 days, n=2
Aqueous photolysis DT50 (days) at pH 7 Value 9 Q2 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 21 K4 Non-persistent
Note -
Water-sediment DT50 (days) 5 Q2 Fast
Water phase only DT50 (days) 15 Q2 Slow

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - W3 Moderately mobile
Koc 240
Notes and range -
Freundlich Kf 34.4 R4 Moderately mobile
Kfoc 442
1/n 1.038
Notes and range Literature data: Kf range 8.0-37.8 (178 for peat) mL/g, Kfoc range 276-677 (276 for peat) mL/g, 1/n range 0.909-1.123, Soils=8
pH sensitivity -


ECOTOXICOLOGY

for parathion-methyl

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 71 J3 Oncorhynchus mykiss Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 3 L3 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 2 -
Birds - Acute LD50 (mg kg-1) 1044 L3 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 2.7 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0073 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.00035 F3 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 3 L3 Scenedemus subspicatus Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 19.5 F4 Moderate
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 40 L3 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for parathion-methyl

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 3 L3 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 45.0 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.17 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.003 JMPR 1995 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.03 UK ACP 1999 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits [LT TWA (USA): 0.2 mg/m3] F3 -
Exposure Routes Public -
Occupational Skin absorption, and to a lesser extent inhalation and ingestion
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

-

-

General human health issues Extremely hazardous
IARC Group 3 carcinogen; USEPA - not likely to be a human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Explosive on heating
Flammable
IMDG Transport Code is 6.1
CLP classification 2013 Handling: H226
Health: H300, H311, H330, H373
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Very toxic: R26/28
T - Toxic: R24
Xn - Harmful: R48/22
H - Handling risks: R5, R10
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S28, S36/37, S45, S60, S61
WHO Classification Ia - Extremely hazardous
US EPA Classification (formulation) I - Danger - Highly toxic
UN Number Active 2783, liquid products 3018
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for parathion-methyl

Language Name
English parathion-methyl
French parathion-methyl
German Parathion-methyl
Danish parathion-methyl
Italian paration-metile
Spanish paratiĆ³n-metil
Greek parathion-methyl
Slovenian parationmetyl
Polish paration metylu
Swedish -
Hungarian -
Dutch parathion-methyl

Record last updated: Wednesday 31 October 2018
Contact: aeru@herts.ac.uk