Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

azocyclotin (Ref: BAY BUE 1452)
** tricyclotin ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Azocyclotin is an organotin acaricide that is not approved for use in the EU and largely considered obsolete. It has a low aqueous solubility, is non-volatile and is not expected to leach to groundwater. Data is limited but is not expected to be persistent in soil systems but may be persistent in aquatic systems under certain conditions. It is highly toxic to mammals and also has a high potential to bioaccumulate. It is thought to be a skin, eye and respiratory system irritant. It is highly toxic to fish and aquatic invertebrates and moderately toxic to birds, honeybees and earthworms.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for azocyclotin

Description: An organotin acaricide used mainly for Phytophagous mite control

Example pests controlled: Mites including spider mites, citrus mites, bulb mites, tomato-russet mite

Example applications: Fruit including apples, pears, strawberries, grapes, citrus; Egg plant

Efficacy & activity: -

Availability status: Unknown

Introduction & key dates: 1978

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Italy
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Nw Zealand; Chile; Australia; Morocco; South Africa; Iran; Lebanon

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C20H35N3Sn
Canonical SMILES C1CCC(CC1)[Sn](C2CCCCC2)(C3CCCCC3)N4C=NC=N4
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) ONHBDDJJTDTLIR-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/3C6H11.C2H2N3.Sn/c3*1-2-4-6-5-3-1;1-3-2-5-4-1;/h3*1H,2-6H2;1-2H;/q;;;-1;+1/rC20H35N3Sn/c1-4-10-18(11-5-1)24(23-17-21-16-22-23,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h16-20H,1-15H2
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Acaricide
Substance group Organometal
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Contact action. Inhibits oxidative phosphorylation.
CAS RN 41083-11-8
EC number 255-209-1
CIPAC number 404
US EPA chemical code -
PubChem CID 91634
Molecular mass (g mol-1) 436.22
PIN (Preferred Identification Name) 1-(tricyclohexylstannyl)-1H-1,2,4-triazole
IUPAC name tri(cyclohexyl)-1H-1,2,4-triazol-1-yltin
CAS name 1-(tricyclohexylstannyl)-1H-1,2,4-triazole
Other status information Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 12B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Tetranychus urticae
Physical state Colourless crystalline powder
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • AgroCare
  • King Tech Corp
  • Arysta LifeScience Corp
  • Bayer
Example products using this active
  • Caligur
  • Peropal
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as a wettable powder.


ENVIRONMENTAL FATE

for azocyclotin

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.04 F3 Low
Solubility - In organic solvents at 20oC (mg l-1) 35000 L3 - Dichloromethane -
30 L2 - Isopropanol -
500 L2 - n-Hexane -
3.5 L2 - Toluene -
Melting point (oC) 210 L3 -
Boiling point (oC) Decomposes before boiling V3 -
Degradation point (oC) 210 L3 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable V3 -
Octanol-water partition coefficient at pH 7, 20oC P 2.40 X 1005 Calculated -
Log P 5.38 T4 High
Bulk density (g ml-1)/Specific gravity 1.34 L3 -
Dissociation constant (pKa) at 25oC 5.36 L3 -
Note: Weak base
Vapour pressure at 20oC (mPa) 2.00 X 10-08 L3 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 7.00 X 10-02 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.50 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 9.93 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 27 W4 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Best available data
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Rapid F3 -
Note Complete hydrolysis occurs in under 10 mins at pH 5, 7 and 9
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - W3 Non-mobile
Koc 4450
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
cyhexatin (Ref: OMS 3029) Soil   -   -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
dicyclohexyltin oxide - Soil - -
cyclohexyltin acid - Soil - -
1,2,4-triazole
(Ref: CGA 71019)
Note: -
- Plant; Animal - -


ECOTOXICOLOGY

for azocyclotin

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 7500 J3 High potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 80 F4 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 5 -
Birds - Acute LD50 (mg kg-1) 144 L3 Coturnix japonica Moderate
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.004 L3 Oncorhynchus mykiss High
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.04 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.16 L3 Scenedemus subspicatus Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) 100 L3 Moderate
Earthworms - Acute 14 day LC50 (mg kg-1) 806 L3 Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Harmful AB1 Typhlodromus pyri -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for azocyclotin

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 80 F4 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.02 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.003 JMPR 2005 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.02 JMPR 2005 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational Occupational exposure may occur through inhalation of dust and dermal contact
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues No further information available

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 Health: H301, H315, H318, H330, H335
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Very toxic: R26
T - Toxic: R25
Xn - Harmful: R41
Xi - Irritant: R37/38
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S26, S28, S45, S61, S36/37/39, S38, S60
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) I - Danger - Highly toxic
UN Number 2786
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for azocyclotin

Language Name
English azocyclotin
French azocyclotin
German Azocyclotin
Danish azocyclotin
Italian azociclotin
Spanish azociclotin
Greek -
Slovenian azociklotin
Polish azocyklocyna
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 23 May 2018
Contact: aeru@herts.ac.uk