Profenofos (Ref: OMS 2004)
Last updated: 25/03/2022
(Also known as: polycron; selecron; curacron; CGA 15324)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An insecticide used on a wide variety of crops to control many pests but mainly Lepidoptera and mites
Aphids; Lygus bugs; Cotton bollworm; Tobacco bud worm; Leaf webber; Cotton leaf-perforator; Beet armyworm; Whitefly (suppression); Spidermites; Caterpillars
Cotton; Maize; Tobacco; Sugarbeet; Soybeans; Potatoes; Ornamentals including jasmine.
-
Current
1975, first reported
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
A molecule with one chiral feature - 2 steroisomers.
C₁₁H₁₅BrClO₃PS
CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl
No data
QYMMJNLHFKGANY-UHFFFAOYSA-N
InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3
Yes
Insecticide, Acaricide
Organophosphate insecticide; Organophosphate acaricide; Organothiophosphate insecticide; Organothiophosphate acaricide
-
-
Synthetic
Non-systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
41198-08-7
255-255-2
461
111401
38779
373.63
-
(RS)-(O-4-bromo-2-chlorophenyl O-ethyl S-propyl phosphorothioate)
O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate
PAN listed Highly Hazardous Chemical
-
Not applicable
Not applicable
1B
Not applicable
Bemisia tabaci , Chrysoperla carnea, Earias vittella , Leucoptera meyricki , Spodoptera littoralis , Tetranychus urticae , many others
Pale yellow liquid
AgroCare King Tech Corp Syngenta
Devi-Soldier Ellak Fertifenophos Hilfos Curacron Selecron 500 EC
-
28
Low
Miscible
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Acetone
-
Miscible
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Methanol
-
Miscible
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Xylene
-
Not applicable
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
124
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
5.01 X 1001
Calculated
-
1.7
Low
1.46
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
Not applicable
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
No dissociation
2.53
Low volatility
1.65 X 10-03
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
7
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
7
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
7
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
-
-
-
-
-
-
-
-
-
-
1.6
R4 R = Peer reviewed scientific publications 4 = Verified data
-
Published literature RL₅₀ range 1.0-2.0 days, 6 field & undercover grown crops, various matrices, n=9
5.4
R4 R = Peer reviewed scientific publications 4 = Verified data
-
Published literature RL₅₀ range 1.0-41.0 days, 6 field crops, various matrices, n=14
-
-
-
-
Stable
W4 W = French database provided by ARVALIS-Institut du Végétal 4 = Verified data
Stable
Other data: DT₅₀ 93 days at pH 5, 14.6 days at pH 7, 5.7 hours at pH 9, all at 20 °C (L3)
-
-
-
-
-
-
Soil adsorption and mobility
-
Slightly mobile
2016
Best available data
-
-
-
-
-
-
-
0.59
Calculated
Low leachability
6.87 X 10-03
Calculated
-
-
Medium
Calculated
-
Slightly mobile
Calculated
-
1186
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Estimated
Threshold for concern
Not available
-
Terrestrial ecotoxicology
358
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
-
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 2 year
-
0.3
-
-
-
-
> 70
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Coturnix japonica
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.095
Apis mellifera
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 0.08
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
High
0.002
P3 P = Other governments and regulators 3 = Unverified data of known source
Pimephales promelas
High
> 0.5
Daphnia magna
Moderate
-
-
-
0.0016
Americamysis bahia
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
358
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
472
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rabbit
-
3.0
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
0.03
JMPR 2007
-
1.0
JMPR 2007
-
-
-
-
-
-
-
-
-
-
List I; List II
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
✓Yes, known to cause a problem
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
Harmful by inhalation
No information available
Health: H302, H312, H332 Environment: H400, H410
II (Moderately hazardous)
3018
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profenofos
profenophos
Profenofos
profenofos
profenfos
profenofos
profenofos
profenofos
-
-
profenofos
Record last updated:
25/03/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242