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GET ADDITIONAL DATA HERE!

profenofos (Ref: OMS 2004)
** polycron ** selecron ** curacron ** CGA 15324 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for profenofos

Description: An insecticide used on a wide variety of crops to control many pests but mainly Lepidoptera and mites

Example pests controlled: Aphids; Lygus bugs; Cotton bollworm; Tobacco bud worm; Leaf webber; Cotton leaf-perforator; Beet armyworm; Whitefly (suppression); Spidermites; Caterpillars

Example applications: Cotton; Maize; Tobacco; Sugarbeet; Soybeans; Potatoes; Ornamentals including jasmine.

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1975, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism A molecule with one chiral feature - 2 steroisomers.
Chemical formula C11H15BrClO3PS
Canonical SMILES CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) QYMMJNLHFKGANY-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide
Substance group Organophosphate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Non-systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 41198-08-7
EC number 255-255-2
CIPAC number 461
US EPA chemical code 111401
PubChem CID 38779
Molecular mass (g mol-1) 373.63
PIN (Preferred Identification Name) -
IUPAC name (RS)-(O-4-bromo-2-chlorophenyl O-ethyl S-propyl phosphorothioate)
CAS name O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate
Other status information PAN listed Highly Hazardous Chemical
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Bemisia tabaci
Chrysoperla carnea
Earias vittella
Leucoptera meyricki
Spodoptera littoralis
Tetranychus urticae
many others
Physical state Pale yellow liquid
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • AgroCare
  • King Tech Corp
  • Syngenta
Example products using this active
  • Devi-Soldier
  • Ellak
  • Fertifenophos
  • Hilfos
  • Curacron
  • Selecron 500 EC
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details -


ENVIRONMENTAL FATE
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Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 28 H4 Low
Solubility - In organic solvents at 20oC (mg l-1) Miscible L2 - Acetone -
Miscible L2 - Methanol -
Miscible L2 - Xylene -
Melting point (oC) Not applicable L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) 124 L3 -
Octanol-water partition coefficient at pH 7, 20oC P 5.01 X 1001 Calculated -
Log P 1.7 H4 Low
Bulk density (g ml-1)/Specific gravity 1.46 L3 -
Dissociation constant (pKa) at 25oC Not applicable L3 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 2.53 H4 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.65 X 10-03 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.59 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 6.87 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 7 L3 Non-persistent
DT50 (lab at 20oC) 7 L3 Non-persistent
DT50 (field) 7 L3 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note: -
Dissipation rate RL50 on plant matrix Value 1.6 R4 -
Note Published literature RL50 range 1.0-2.0 days, 6 field & undercover grown crops, various matrices, n=9
Dissipation rate RL50 on and in plant matrix Value 5.4 R4 -
Note Published literature RL50 range 1.0-41.0 days, 6 field crops, various matrices, n=14
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable W4 -
Note Other data: DT50 93 days at pH 5, 14.6 days at pH 7, 5.7 hours at pH 9, all at 20 degC (L3)
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - H3 Slightly mobile
Koc 2016
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY
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Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 1186 Q2 Estimated Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 358 L3 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 0.3 -
Birds - Acute LD50 (mg kg-1) 70 L3 Coturnix japonica High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.08 L3 Oncorhynchus mykiss High
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.5 F4 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.0016 F3 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 0.095 F4 High
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION
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General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 358 L3 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) 472 L3 Rabbit -
Mammals - Inhalation LC50 (mg l-1) 3.0 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.03 JMPR 2007 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 1.0 JMPR 2007 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

General human health issues Harmful by inhalation

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 -
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R20/21/22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S36/37, S60, S61
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number 3018
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS
for profenofos

Language Name
English profenofos
French profenophos
German Profenofos
Danish profenofos
Italian profenfos
Spanish profenofos
Greek profenofos
Slovenian profenofos
Polish profenofos
Swedish -
Hungarian -
Dutch profenofos

Record last updated: Monday 02 July 2018
Contact: aeru@herts.ac.uk