Select Option
Home
A to Z
Search
Terms & Conditions
Support Information
Purchasing & Other Services
Video User Guides
GET ADDITIONAL DATA HERE!

prometryn (Ref: C 34161)
** prometryne ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for prometryn

Description: A herbicide used to control annual grasses and broad-leaved weeds in a variety of crops

Example pests controlled: Grasses including barnyard grass, goosegrass, ryegrass, prairies grass; Broad-leaved weeds including deadnettle, nightshade, chickweed, fathen, common spurry

Example applications: Cotton; Celery; Pigeon peas; Dill; Potatoes; Sunflowers; Carrots; Peanuts

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1964, first registered USA

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires Essential use only
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C10H19N5S
Canonical SMILES CC(C)NC1=NC(=NC(=N1)SC)NC(C)C
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) AAEVYOVXGOFMJO-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C10H19N5S/c1-6(2)11-8-13-9(12-7(3)4)15-10(14-8)16-5/h6-7H,1-5H3,(H2,11,12,13,14,15)
2D structure diagram/image available? Yes

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Common Name Relationship Link
Prometryn - Click here for the CCDC structure diagram

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Triazine
Minimum active substance purity 96%
Known relevant impurities -
Substance origin Synthetic
Mode of action A selective, systemic, contact and residual triazine, a photosynthetic electron transport inhibitor at the photosystem II receptor site
CAS RN 7287-19-6
EC number 230-711-3
CIPAC number 93
US EPA chemical code 080805
PubChem CID 4929
Molecular mass (g mol-1) 241.36
PIN (Preferred Identification Name) -
IUPAC name N2,N4-diisopropyl-6-methylthio-1,3,5-triazine-2,4-diamine
CAS name N,N'-bis(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine
Other status information Potential groundwater contaminant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) C1
Herbicide Resistance Classification (WSSA) 5
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state Colourless crystalline solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Ciba Geigy
  • Makhteshim-Agan
Example products using this active
  • Caparol
  • Gesaguard
  • Primetol Q
  • Prometex
UK LERAP status None
Formulation and application details Often supplied as a wettable powder.


ENVIRONMENTAL FATE

for prometryn

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 33 K4 Low
Solubility - In organic solvents at 20oC (mg l-1) 240000 C4 - Acetone -
5500 C4 - Hexane -
160000 C4 - Methanol -
170000 C4 - Toluene -
Melting point (oC) 119 L3 -
Boiling point (oC) 300 Q3 -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 2.19 X 1003 Calculated -
Log P 3.34 G4 High
Bulk density (g ml-1)/Specific gravity 1.15 L3 -
Dissociation constant (pKa) at 25oC 4.1 Q3 - @ 25 degC -
Note: Weak base, pKb = 9.95
Vapour pressure at 20oC (mPa) 0.13 G4 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.20 X 10-03 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.59 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.13 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 41 K4 Moderately persistent
DT50 (lab at 20oC) 41 K4 Moderately persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Other sources: DT50 60 days (DW4)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 30 K4 Stable
Note Degraded by UV light
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable K4 -
Note Stable under normal environmental conditions, hydrolysed in acidic and alkaline media
Water-sediment DT50 (days) 38 Q3 Moderately fast
Water phase only DT50 (days) 56 K4 Stable

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - G3 Moderately mobile
Koc 400
Notes and range -
Freundlich Kf 53.26 R4 Non-mobile
Kfoc 4330
1/n 0.86
Notes and range Kf range 4.22-165 mL/g, Kfoc range 122-12692 mL/g, 1/n range 0.57-1.18, Soils=3
pH sensitivity -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2-hydroxy-propazine - Soil - -
2,4-bis(isopropylamino)-6-hydroxy-S-triazine - Soil (Aerobic) - -
2-methylthio-4-amino-6-isopropylamino-S-triazine
(Ref: GS-11354)
- Soil - -
hydroxypropazine
(Ref: GS-11526)
- Soil - -


ECOTOXICOLOGY

for prometryn

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 85 F4 Whole fish Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 2000 L3 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 750 -
Birds - Acute LD50 (mg kg-1) > 2150 G4 Anas platyrhynchos Low
Birds - Short term dietary (LC50/LD50) > 500 ppm Q3 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 5.5 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.08 P3 Cyprinus carpio, 60 day Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 12.66 L3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 2 F3 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 1.4 F3 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.0105 F3 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.002 F4 Scenedesmus acutus High
Algae - Chronic 96 hour NOEC, growth (mg l-1) > 0.0025 P3 Chlamydomonas reinhardtii Moderate
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 99 G4 Moderate
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) 153 K4 Moderate
Earthworms - Chronic NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms Acute LC50 (mg kg-1) - - -
Chronic NOEC (mg kg-1) - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Harmless Dose: 10 g ha-1
AA2 Chrysoperla carnea
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for prometryn

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 L3 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2020 L3 Rabbit -
Mammals - Inhalation LC50 (mg l-1) > 5.17 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.01 L3 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B0; C0; D0; E3

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Possible kidney and liver toxicant
Possible blood toxicant
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 Health: H332
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases N - Dangerous for the environment: R50/53
EC Safety Classification Click here to view information omn the EU safety phrases S23, S24/25
WHO Classification III - Slightly hazardous
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for prometryn

Language Name
English prometryn
French prometryne
German Prometryn
Danish prometryn
Italian prometrina
Spanish prometrina
Greek -
Slovenian prometrin
Polish prometryn
Swedish -
Hungarian prometryn
Dutch -

Record last updated: Wednesday 27 November 2019
Contact: aeru@herts.ac.uk