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propazine (Ref: G 30028)
** prozinex ** propazin ** gesamil ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for propazine

Description: A chlorotriazine herbicide used for control of broad-leaved weeds and annual grasses

Example pests controlled: Annual morning glory; Pigweed; Smartweed; Carpet weed; Lambsquarter; Ragweed; Velvetleaf

Example applications: Sorghum; Corn; Some umbelliferae vegetables; Carrots; Fennel; Ornamentals; Greenhouse use

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1998, USA

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur -
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C9H16ClN5
Canonical SMILES CC(C)NC1=NC(=NC(=N1)Cl)NC(C)C
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) WJNRPILHGGKWCK-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C9H16ClN5/c1-5(2)11-8-13-7(10)14-9(15-8)12-6(3)4/h5-6H,1-4H3,(H2,11,12,13,14,15)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Triazine
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Selective, systemic, absorbed by roots and translocated
CAS RN 139-40-2
EC number 205-359-9
CIPAC number 92
US EPA chemical code 080808
PubChem CID 4937
Molecular mass (g mol-1) 229.71
PIN (Preferred Identification Name) -
IUPAC name 6-chloro-N2,N4-diisopropyl-1,3,5-triazine-2,4-diamine
CAS name 6-chloro-N,N'-bis(1-methylethyl)-1,3,5-triazine-2,4-diamine
Other status information Marine pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) C1
Herbicide Resistance Classification (WSSA) -
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state Colourless crystalline solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Griffin Corporation
  • Ciba Geigy
  • Makhteshim Agan
Example products using this active
  • Milogard
  • Milo-Pro
  • Gesamil
  • Milocep
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Often supplied as water-dispersible granules or wettable powder.


ENVIRONMENTAL FATE

for propazine

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 8.6 K4 Low
Solubility - In organic solvents at 20oC (mg l-1) 6200 L3 - Benzene -
5000 L3 - Diethyl ether -
2500 L3 - Carbon tetrachloride -
Melting point (oC) 213 L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 8.91 X 1003 Calculated -
Log P 3.95 K4 High
Bulk density (g ml-1)/Specific gravity 1.16 L3 -
Dissociation constant (pKa) at 25oC 1.7 L3 -
Note: Very weak base
Vapour pressure at 20oC (mPa) 0.004 G4 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.79 X 10-04 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 3.86 Calculated High leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.07 X 10+00 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 131 K4 Persistent
DT50 (lab at 20oC) 135 F3 Persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Best available data
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 0.8 K3 Fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 83 K3 Moderately persistent
Note Stable under normal environmental conditions, hydrolysed by acids and alkalis at elevated temperatures
Water-sediment DT50 (days) 77 K4 Moderately fast
Water phase only DT50 (days) 77 K4 Stable

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - G3 Moderately mobile
Koc 154
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
hydroxypropazine Soil   -   -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
2-hydroxy-4,6-bis(isopropylamino)-s-triazine - Soil (Aerobic); Water (Photolysis) - -
4,6-bis(isopropylamino)-s-triazine - Soil (Aerobic) - -
2-chloro-4-amino-6-isopropylamino-s-triazine - Soil (Aerobic & Anaerobic) - -


ECOTOXICOLOGY

for propazine

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 62 Q2 Estimated Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 3840 G4 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) 13 L3 Rat High
(ppm diet) 200 -
Birds - Acute LD50 (mg kg-1) 10000 L3 Anas platyrhynchos Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 17.5 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 17.7 K2 Unknown species Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.88 F3 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.18 F3 Cyanobacteria Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 16 K4 Moderate
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for propazine

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 3840 G4 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 3100 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 2.04 L3 Rabbit -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Endocrine issues - Induction of aromatase activity and increase of estrogen production

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 Human: H351
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Carcinogen category 3: R40
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S36/37, S60, S61
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) IV - Caution - Not acutely toxic
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for propazine

Language Name
English propazine
French propazine
German Propazin
Danish propazin
Italian propazina
Spanish propazina
Greek -
Slovenian propazin
Polish propazyna
Swedish -
Hungarian -
Dutch propazine

Record last updated: Thursday 24 May 2018
Contact: aeru@herts.ac.uk