Pyrazoxyfen (Ref: SL 49)
Last updated: 19/01/2023
(Also known as: pyrazoxyfene)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A pre- or post-emergence herbicide used to control annual and perennial weeds mainly in rice crops
Barnyard grass
Rice; Cereals
-
Current
1985, Japan
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
-
Not applicable
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₂₀H₁₆Cl₂N₂O₃
CC1=NN(C(=C1C(=O)C2=C(C=C(C=C2)Cl)Cl)OCC(=O)C3=CC=CC=C3)C
No data
FKERUJTUOYLBKB-UHFFFAOYSA-N
InChI=1S/C20H16Cl2N2O3/c1-12-18(19(26)15-9-8-14(21)10-16(15)22)20(24(2)23-12)27-11-17(25)13-6-4-3-5-7-13/h3-10H,11H2,1-2H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
pyrazoxyfen
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Herbicide
Pyrazole herbicide; Benzoylpyrazole herbicide
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-
Synthetic
Selective, systemic absorbed through young stems and roots. Bleaching: inhibition of 4-hydroxyphenyl-pyruvate-dioxygenase.
71561-11-0
615-306-5
None allocated
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92383
No data found
403.26
-
2-[4-(2,4-dichlorobenzoyl)-1,3-dimethylpyrazol-5-yloxy]acetophenone
2-[[4-(2,4-dichlorobenzoyl)-1,3-dimethyl-1H-pyrazol-5-yl]oxy]-1-phenylethanone
-
-
F2
27
Not applicable
Not applicable
-
Colourless crystals
900
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
157000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
325000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Benzene
-
16000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethanol
-
710
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Hexane
-
111
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
-
-
-
4.90 X 1003
Calculated
-
3.69
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
-
-
-
-
-
-
1.37
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
0.048
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
2.15 X 10-05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
10
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
Best available data
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-
-
-
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-
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-
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-
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Soil adsorption and mobility
-
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source
Slightly mobile
2023
Estimated
-
-
-
-
-
-
-
0.69
Calculated
Low leachability
1.01 X 10-02
Calculated
-
-
Medium
Calculated
-
Slightly mobile
Calculated
-
-
-
-
-
-
None
Terrestrial ecotoxicology
1644
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
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-
-
-
-
-
-
-
-
-
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-
0.79
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
-
-
-
> 40
Daphnia magna
Moderate
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-
-
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HUMAN HEALTH AND PROTECTION
High (class III)
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-
1644
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
5000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
0.28
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
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-
-
-
-
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EU MRL pesticide database 
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-
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
No further information available
No information available
Health: H302 Environment: H400
II (Moderately hazardous)
-
-
pyrazoxyfen
pyrazoxyfène
Pyrazoxyfen
pyrazoxyfen
pirazossifen
piraoxifen
-
pyrazoksyfen
-
-
-
Record last updated:
19/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242