| quinalphos (Ref: ENT 27397) |
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GENERAL INFORMATION 
for quinalphos
Description: A broad-spectrum insecticide and acaricide used against a range of common insect pests
Example pests controlled: Caterpillars; Aphids; Mealybugs; Mites; Bollworms; Leaf hoppers; Borers
Example applications: Rape; Peanuts; Sorghum; Wheat; Sugarcane; Fibre crops; Cotton; Vines & grapes
Efficacy & activity: -
Availability status: Unknown
Introduction & key dates: circa 1970
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Expired |
| EU Candidate for substitution (CfS) | Not applicable |
| Listed in EU database | Yes |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Chemical structure:
| Isomerism | - |
| Chemical formula | C12H15N2O3PS |
| Canonical SMILES | CCOP(=S)(OCC)OC1=NC2=CC=CC=C2N=C1 |
| Isomeric SMILES | No data |
| International Chemical Identifier key (InChIKey) | JYQUHIFYBATCCY-UHFFFAOYSA-N |
| International Chemical Identifier (InChI) | InChI=1S/C12H15N2O3PS/c1-3-15-18(19,16-4-2)17-12-9-13-10-7-5-6-8-11(10)14-12/h5-9H,3-4H2,1-2H3 |
| 2D structure diagram/image available? | Yes |
General status:
| Pesticide type | Insecticide, Acaricide | |||
| Substance group | Organophosphate | |||
| Minimum active substance purity | - | |||
| Known relevant impurities | - | |||
| Substance origin | Synthetic | |||
| Mode of action | Contact and stomach action. Non-systemic. Acetylcholinesterase (AChE) inhibitor. | |||
| CAS RN | 13593-03-8 | |||
| EC number | 237-031-6 | |||
| CIPAC number | 449 | |||
| US EPA chemical code | - | |||
| PubChem CID | 26124 | |||
| Molecular mass (g mol-1) | 298.3 | |||
| PIN (Preferred Identification Name) | O,O-diethyl O-quinoxalin-2-yl phosphorothioate | |||
| IUPAC name | O,O-diethyl O-quinoxalin-2-yl phosphorothioate | |||
| CAS name | O,O-diethyl O-2-quinoxalinyl phosphorothioate | |||
| Other status information | Marine Pollutant | |||
| Relevant Environmental Water Quality Standards | - | |||
| Herbicide Resistance Classification (HRAC) | Not applicable | |||
| Herbicide Resistance Classification (WSSA) | Not applicable | |||
| Insecticide Resistance Classification (IRAC) | 1B | |||
| Fungicide Resistance Classification (FRAC) | Not applicable | |||
| Examples of recorded resistance | Bemisia tabaci Helicoverpa armigera Myzus persicae Pectinophora gossypiella Spodoptera litura many others |
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| Physical state | Colourless crystals | |||
| Related substances & organisms | - | |||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use as a pesticide under EC Regulation 1107/2009 | |||
| Formulation and application details | Available as emulsifiable concentrates, ULVs, granules, dusts and wettable powders. | |||
ENVIRONMENTAL FATE
for quinalphos
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 17.8 | L3 | Low | |
| Solubility - In organic solvents at 20oC (mg l-1) | 250000 | L3 - Hexane | - | |
| Melting point (oC) | 31.5 | L3 | - | |
| Boiling point (oC) | - | - | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | - | - | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 2.75 X 1004 | Calculated | - |
| Log P | 4.44 | L3 | High | |
| Bulk density (g ml-1)/Specific gravity | 1.235 | L3 | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 20oC (mPa) | 0.346 | L3 | Low volatility | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 4.70 X 10-03 | V3 | Non-volatile | |
GUS leaching potential index  |
1.10 | Calculated | Low leachability | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 2.09 X 10-02 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Medium | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
General biodegradability | - |
| Soil degradation (days) (aerobic) | DT50 (typical) | 21 | L3 | Non-persistent |
| DT50 (lab at 20oC) | - | - | - | |
| DT50 (field) | - | - | - | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| DT50 modelling endpoint | - | - | - | |
| Note | Best available data | |||
| Dissipation rate RL50 on plant matrix | Value | 1.4 | R3 | - |
| Note | Tea, green leaves, n=1 | |||
| Dissipation rate RL50 on and in plant matrix | Value | 2.9 | R4 | - |
| Note | Published literature RL50 range 1.2-8.3 days, 9 field crops, various matrices, n=12 | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | - | - | - |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | 39 | L2 | Moderately persistent |
| Note | pH sensitive: DT50 23 days at pH 3, 39 days at pH 6, 26 days at pH 9, all at 25 degC | |||
| Water-sediment DT50 (days) | - | - | - | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | S1 | Slightly mobile |
| Koc | 1465 | |||
| Notes and range | Estimated | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
Key metabolites:
| Metabolite | Formation medium | Estimated maximum occurrence fraction | 1107/2009 relevancy |
|
| 2-hydroxyquinoxaline | Soil | - | - | |
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | - | - | - |
| CT50 (days) | - | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 71 | L3 Rat | High | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | L2 Rat, 2 year | - |
| (ppm diet) | 3 | - | ||
| Birds - Acute LD50 (mg kg-1) | 4.3 | L3 Coturnix japonica | High | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | 0.005 | L3 Oncorhynchus mykiss | High | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | 0.00066 | L3 Daphnia magna | High | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | - | - | - | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | - | - | - | |
| Honeybees | Contact acute 48 hour LD50 (μg bee-1) | 0.07 | R3 Apis mellifera | High |
| Oral acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Unknown mode acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | 118.4 | L3 | Moderate | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50 / EC50 / NOEC / % Effect | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for quinalphos
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 71 | L3 Rat | High | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | 1750 | L3 Rat | - | |
| Mammals - Inhalation LC50 (mg l-1) | 0.45 | L3 Rat | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | - | - | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
| AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | List I; List II | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | - | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water Standards | - | - | - | |
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
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| General human health issues | Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin, | |||||||
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
Corrosive when molten IMDG Transport Code is usually 6.1 |
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| CLP classification 2013 | Health: H301, H312 Environment: H400, H410 |
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| EC Risk Classification |
T - Toxic: R25 Xn - Harmful: R21 N - Dangerous for the environment: R50, R53 |
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| EC Safety Classification |
S1/2, S22, S36/37, S45, S60, S61 | |||
| WHO Classification | II | - | Moderately hazardous | |
| US EPA Classification (formulation) | II | - | Warning - Moderately toxic | |
| UN Number | Usually 2783 or 3018 | |||
| Waste disposal & packaging |
Packaging Group II (medium danger) | |||
| Language | Name |
| English | quinalphos |
| French | quinalphos |
| German | Quinalphos |
| Danish | quinalphos |
| Italian | quinalfos |
| Spanish | quinalfos |
| Greek | quinalphos |
| Slovenian | kvinalfos |
| Polish | kwinalfos |
| Swedish | - |
| Hungarian | - |
| Dutch | quinalfos |
Record last updated: Tuesday 04 June 2019
Contact: aeru@herts.ac.uk