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sethoxydim (Ref: BAS 9052H)
** sethoxydime ** cyethoxydim ** NP 55 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for sethoxydim

Description: A post-emergence, selective, annual and perennial grass weed herbicide

Example pests controlled: Barnyardgrass; Crabgrass; Cupgrass; Foxtail; Tall fescue; Johnsongrass; Junglerice; Tame oats; Itchgrass; Volunteer cereals; Stinkgrass

Example applications: Alfalfa; Citrus; Sorghum; Corn; Small grains; Rice; Ornamental grass; Oilseed rape; Sugarbeet; Vegetables

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1983, Introduced USA

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism A chiral molecule
Chemical formula C17H29NO3S
Canonical SMILES CCCC(=C1C(=O)CC(CC1=O)CC(C)SCC)NOCC
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) CSPPKDPQLUUTND-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C17H29NO3S/c1-5-8-14(18-21-6-2)17-15(19)10-13(11-16(17)20)9-12(4)22-7-3/h12-13,19H,5-11H2,1-4H3/b18-14+
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Cyclohexadione
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Selective, systemic absorbed mainly by foliage. An acetyl CoA carboxylase inhibitor (ACCase).
CAS RN 74051-80-2
EC number 277-682-3
CIPAC number 401
US EPA chemical code 121001
PubChem CID 52923
Molecular mass (g mol-1) 327.48
PIN (Preferred Identification Name) (5E)-2-[(1E)-N-ethoxybutanimidoyl]-5-[(2E)-2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one
IUPAC name (5RS)-2-[(EZ)-1-(ethoxyimino)butyl]-5-[(2RS)-2-(ethylthio)propyl]-3-hydroxycyclohex-2-en-1-one
CAS name 2-(1-(ethoxyimino)butyl)-5-(2-(ethylthio)propyl)-3-hydroxy-2-cyclohexen-1-one
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) A
Herbicide Resistance Classification (WSSA) 1
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Many recorded cases
Alopecurus myosuroides
Avena fatua
Avena sterilis
Avena sterilis ludoviciana
Digitaria sanguinalis
Physical state Oily amber liquid
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • BASF
  • Bayer CropScience
  • Nippon Soda
Example products using this active
  • Conclude
  • Headline G
  • Poast
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as an emulsifiable concentrate.


ENVIRONMENTAL FATE

for sethoxydim

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 4700 G4 High
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting point (oC) Not applicable L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 4.47 X 1001 Calculated -
Log P 1.65 G4 Low
Bulk density (g ml-1)/Specific gravity 1.043 L3 -
Dissociation constant (pKa) at 25oC 4.58 V3 -
Note: Weak acid
Vapour pressure at 20oC (mPa) 0.013 L3 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.39 X 10-06 H4 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.49 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 4.15 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 1.2 K4 Non-persistent
DT50 (lab at 20oC) 1 K4 Non-persistent
DT50 (field) 5 F3 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Other sources: DT50 5-25 days (Q3), 1 day sandy soils (R3)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value 0.04 R3 -
Note Navy bean leaves, n=1
Aqueous photolysis DT50 (days) at pH 7 Value 0.02 K4 Fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 242 K3 Persistent
Note -
Water-sediment DT50 (days) 130 Q2 Slow
Water phase only DT50 (days) 17.8 K3 Slow

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - G3 Moderately mobile
Koc 75
Notes and range Literature values indicate little adsorption with values typicaly between 50 and 100 ml/g
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
sethoxydim-sulfoxide This metabolite may cause environmental pollution, click here for further information Soil   0.560   Major fraction
6-(2-ethylsulfinylpropyl)-4-oxy-2-propyl-4,5,6,7-tetrahydro-1,3,benzoxazole This metabolite may cause environmental pollution, click here for further information Soil   0.190   Major fraction


ECOTOXICOLOGY

for sethoxydim

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 22.5 F4 Whole fish Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 2676 L3 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) 17.2 L2 Rat, 2 year High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 5000 L3 Coturnix japonica Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) > 170 F3 Oncorhynchus mykiss Low
Fish - Chronic 21 day NOEC (mg l-1) 0.18 P3 Lepomis macrochirus, 4 day Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 1.5 L3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) > 0.700 F3 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.28 F3 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.64 D4 Unknown species Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 10 K4 Moderate
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) > 542 Q3 Moderate
Earthworms - Chronic NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms Acute LC50 (mg kg-1) - - -
Chronic NOEC (mg kg-1) - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Moderately harmful Dose: 3160 g ha-1
AA3 Typhlodromus pyri
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect Harmless Dose: 3160 g ha-1
AA3 Chrysoperla carnea
-
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for sethoxydim

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 2676 L3 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 6.28 L3 Rat, 4 hr -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.14 L3 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public -
Occupational May be absorbed through the skin
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B0; C0; D0; E3

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Possible thyroid, liver and bone marrow toxicant
May cause lung damage if swallowed
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 Not classified: Obsolete
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R65
N - Dangerous for the environment: R51/53
EC Safety Classification Click here to view information omn the EU safety phrases -
WHO Classification III - Slightly hazardous
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for sethoxydim

Language Name
English sethoxydim
French séthoxydime
German Sethoxydim
Danish sethoxydim
Italian setossidim
Spanish setoxidim
Greek -
Slovenian setoksidim
Polish setoksydim
Swedish -
Hungarian -
Dutch setoxidim

Record last updated: Wednesday 27 November 2019
Contact: aeru@herts.ac.uk