| 2-aminobutane |
 |
Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
SUMMARY
2-aminobutane is a fumigant fungicide that does not have approval for use in the EU. It is highly soluble in water and is extremely volatile. It is not persistent in soil systems. It is moderately toxic to mammals and has a high potential for bioaccumulation. It is a recognised irritant. It is moderately toxic to birds, earthworms, honeybees and most aquatic organisms. GENERAL INFORMATION 
for 2-aminobutane
Description: A fumigant fungicide permitted for use only on stored seed potatoes
Example pests controlled: Gangrene; Silver spot; Scurf; Post-harvest decay; Blue & green moulds
Example applications: Seed potatoes; Oranges; Ornamentals including chrysanthemums, gladioli
Efficacy & activity: -
Availability status: Unknown
Introduction & key dates: 1972, USA
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Expired |
| EU Candidate for substitution (CfS) | Not applicable |
| Listed in EU database | Yes |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Chemical structure:
| Isomerism | One of the four isomeric amines of butane |
| Chemical formula | C4H11N |
| Canonical SMILES | CCC(C)N |
| Isomeric SMILES | No data |
| International Chemical Identifier key (InChIKey) | BHRZNVHARXXAHW-UHFFFAOYSA-N |
| International Chemical Identifier (InChI) | InChI=1S/C4H11N/c1-3-4(2)5/h4H,3,5H2,1-2H3 |
| 2D structure diagram/image available? | Yes |
General status:
| Pesticide type | Fungicide | |||
| Substance group | Alkylamine | |||
| Minimum active substance purity | - | |||
| Known relevant impurities | - | |||
| Substance origin | Synthetic | |||
| Mode of action | Fumigant | |||
| CAS RN | 13952-84-6 | |||
| EC number | 237-732-7 | |||
| CIPAC number | 248 | |||
| US EPA chemical code | 004214 | |||
| PubChem CID | 24874 | |||
| Molecular mass (g mol-1) | 73.14 | |||
| PIN (Preferred Identification Name) | - | |||
| IUPAC name | (RS)-2-aminobutane | |||
| CAS name | 2-butanamine | |||
| Other status information | Chemical subject to PIC regulations | |||
| Relevant Environmental Water Quality Standards | - | |||
| Herbicide Resistance Classification (HRAC) | Not applicable | |||
| Herbicide Resistance Classification (WSSA) | Not applicable | |||
| Insecticide Resistance Classification (IRAC) | Not applicable | |||
| Fungicide Resistance Classification (FRAC) | Not known | |||
| Examples of recorded resistance | - | |||
| Physical state | Colourless liquid | |||
| Related substances & organisms | - | |||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use as a pesticide under EC Regulation 1107/2009 | |||
| Formulation and application details | - | |||
ENVIRONMENTAL FATE
for 2-aminobutane
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 120000 | CA3 | High | |
| Solubility - In organic solvents at 20oC (mg l-1) | Miscible | L3 - Ethanol | - | |
| Miscible | L3 - Methanol | - | ||
| Miscible | L3 - Acetone | - | ||
| Melting point (oC) | -104 | CA2 | - | |
| Boiling point (oC) | 63 | V3 | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | -19 | V3 - (closed cup) | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 5.50 X 1000 | Calculated | - |
| Log P | 0.74 | CA3 | Low | |
| Bulk density (g ml-1)/Specific gravity | 0.724 | CA3 | - | |
| Dissociation constant (pKa) at 25oC | 10.56 | CA3 | - | |
| Note: Very weak acid | ||||
| Vapour pressure at 20oC (mPa) | 1.93 X 1007 | B5 | Highly volatile | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 2.15 X 10-03 | V3 | Non-volatile | |
GUS leaching potential index  |
- | - | - | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | - | - | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Low | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
General biodegradability | - |
| Soil degradation (days) (aerobic) | DT50 (typical) | 0.2 |
Q2 | Non-persistent |
| DT50 (lab at 20oC) | - | - | - | |
| DT50 (field) | - | - | - | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| DT50 modelling endpoint | - | - | - | |
| Note | Best available data | |||
| Dissipation rate RL50 on plant matrix | Value | - | - | - |
| Note | - | |||
| Dissipation rate RL50 on and in plant matrix | Value | - | - | - |
| Note | - | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | - | - | - |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | - | - | - |
| Note | - | |||
| Water-sediment DT50 (days) | - | - | - | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | - | - |
| Koc | - | |||
| Notes and range | - | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
ECOTOXICOLOGY
for 2-aminobutane
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | Low risk | Q3 Based on LogP < 3 | Low potential |
| CT50 (days) | - | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 350 | B4 Rat | Moderate | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | - | - |
| (ppm diet) | - | - | ||
| Birds - Acute LD50 (mg kg-1) | > 250 | Q2 Gallus gallus | Moderate | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | > 46 | A5 Lepomis macrochirus | Moderate | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | > 40.4 | A5 Daphnia magna | Moderate | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | > 0.54 | B4 Unknown species | Moderate | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | - | - | - | |
| Honeybees | Contact acute 48 hour LD50 (μg bee-1) | > 100 | E3 | Low |
| Oral acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Unknown mode acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | - | - | - | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50 / EC50 / NOEC / % Effect | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for 2-aminobutane
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
Low (class I) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 350 | B4 Rat | Moderate | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | > 2500 | L3 Rabbit | - | |
| Mammals - Inhalation LC50 (mg l-1) | - | - | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | 0.01 | F2 | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
| AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | - | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | Small risk of inhalation exposure from treated sites or from treated food commodities Source: HSDB |
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| Occupational | Potentially via inhalation and dermal contact Source: HSDB |
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| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water Standards | - | - | - | |
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
- |
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
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| General human health issues | High inhalation exposure can cause pulmonary edema and asphyxiation | |||||||
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
Very corrosive Flammable |
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| CLP classification 2013 | Handling: H225 Health: H302, H314, H332 Environment: H400 |
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| EC Risk Classification |
Xn - Harmful: R20/22 H - Handling risks: R11, R35 N - Dangerous for the environment: R50 |
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| EC Safety Classification |
S1/2, S9, S16, S26, S28, S45, S61, S36/37/39 | |||
| WHO Classification | NL | - | Not listed | |
| US EPA Classification (formulation) | II | - | Warning - Moderately toxic | |
| UN Number | 1992 | |||
| Waste disposal & packaging |
Packaging Group II (medium danger) | |||
TRANSLATIONS
for 2-aminobutane
| Language | Name |
| English | 2-aminobutane |
| French | 2-amino butane |
| German | 2-Aminobutan |
| Danish | 2-aminobutan |
| Italian | 2-aminobutano (alias sec-butilammina) |
| Spanish | 2-aminobutano |
| Greek | - |
| Slovenian | 2-aminobutan |
| Polish | 2-aminobutan |
| Swedish | - |
| Hungarian | - |
| Dutch | - |
Record last updated: Monday 28 May 2018
Contact: aeru@herts.ac.uk