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sulcotrione (Ref: SC 0051)
** sulcotrion ** ICI A0051 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for sulcotrione

Description: A herbicide for grass and broad-leaved weed control in maize, sugar cane and other crops

Example pests controlled: Pigweed; Goosefoot; Crabgrass; Common purslane; khaki weed; Bladder weed; Italian ryegrass; Dwarf marigold; Nightshade

Example applications: Maize; Sweetcorn; Sorghum; Sunflowers; Soybean; Cotton; Wheat; Broccoli; Carrots; Curcubits; Tobacco

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1991

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Germany/Spain
Date inclusion expires 31/08/2022
EU Candidate for substitution (CfS) Yes - low ADI / ARfD / AOEL
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C14H13ClO5S
Canonical SMILES CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) PQTBTIFWAXVEPB-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Triketone
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - hydrogen cyanide 80mg/kg, toluene 4g/kg
Substance origin Synthetic
Mode of action Absorbed mainly by the leaves but also some root uptake. Bleaching: inhibition of 4-hydroxyphenyl-pyruvate-dioxygenase.
CAS RN 99105-77-8
EC number -
CIPAC number 723
US EPA chemical code -
PubChem CID 91760
Molecular mass (g mol-1) 328.77
PIN (Preferred Identification Name) 2-[2-chloro-4-(methanesulfonyl)benzoyl]cyclohexane-1,3-dione
IUPAC name 2-(2-chloro-4-mesylbenzoyl)cyclohexane-1,3-dione
CAS name 2-[2-chloro-4-(methylsulfonyl)benzoyl]-1,3-cyclohexanedione
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) F2
Herbicide Resistance Classification (WSSA) 27
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state White solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Syngenta
Example products using this active
  • Mikado
  • Cyclone
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as a suspension concentrate that is mixed with water and applied as a spray.


ENVIRONMENTAL FATE

for sulcotrione

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 165.0 R4 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 2000 A5 - Xylene -
190000 A5 - Dichloromethane -
48000 A5 - Acetone -
300 A5 - 1-Octanol -
Melting point (oC) 139 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 170 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 2.00 X 10-02 Calculated -
Log P -1.7 A5 Low
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC 3.13 A5 -
Note: Weak acid
Vapour pressure at 20oC (mPa) 5.00 X 10-03 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 6.0 X 10-07 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 3.43 Calculated High leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 4.11 X 10-01 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 285nm = 15239, 283.5nm = 16868, 259 nm = 20364 A5 -
Surface tension (mN m-1) 69.0 A5 at 20oC, 90% solution -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 25 A5 Non-persistent
DT50 (lab at 20oC) 25.3 A5 Non-persistent
DT50 (field) 3.6 A5 Non-persistent
DT90 (lab at 20oC) 100.2 A5 -
DT90 (field) 18.4 A5 -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 10.8-89.7 days, DT90 range 47-246 days; field studies DT50 range 1.2-11.4 days, DT90 range 6.9-38 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 25.6 A5 Slow
Note pH sensitive: DT50 13 days at pH 4, 40.9 days at pH 9, all data for 5 cm depth and seasonal mean values. Degradation slower at 30 cm depth.
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable at pH 5 to pH 9, temp 25-40 Deg C
Water-sediment DT50 (days) 63.9 A5 Moderately fast
Water phase only DT50 (days) 9.5 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 1.05 A5 Mobile
Kfoc 36
1/n 0.839
Notes and range EU dossier Kf range 0.29-2.26, Kfoc range 17-58 mL/g, 1/n range 0.812-0.888, Soils=6
pH sensitivity Predominantly OC-dependent but pH-dependent to a minor extent

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
2-chloro-4-methylsulfonyl-benzoic acid This metabolite may cause environmental pollution, click here for further information Soil   0.603   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
4-hydroxyphenyl pyruvate - Rat (Blood) - -
4-hydroxy-sulcotrione, 2-[2-chloro-4-(methylsulfonyl)benzoyl]-4-hydroxycyclohexane-1,3-dione sulcotrione metabolite M02 Rat (Urinary) - -
5-hydroxy-sulcotrione, 2-[2-chloro-4-(methylsulfonyl)benzoyl]-5-hydroxycyclohexane-1,3-dione sulcotrione metabolite M04 Rat (Urinary) - -


ECOTOXICOLOGY

for sulcotrione

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) > 0.5 L2 Rat, 2 year High
(ppm diet) > 100 -
Birds - Acute LD50 (mg kg-1) > 1350 A5 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) > 1259 mg kg bw-1 day-1 A5 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 227 A5 Oncorhynchus mykiss Low
Fish - Chronic 21 day NOEC (mg l-1) 3.2 A4 Oncorhynchus mykiss, Juvenile growth Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 848 A5 Daphnia magna Low
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) > 75 A5 Daphnia magna Low
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.051 A5 Lemna gibba Moderate
Non-target plants 7.0 A5 Lactuca sativa
Seedling emergence, ER50
as g/ha
-
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 1.2 A5 Raphidocelis subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 200 A5 Low
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 50 A5 Moderate
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) > 1000 A5 Low
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 450 >, 48 hour
A5 Aphidius rhopalosiphi, adult
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 450 >, 7 day
A5 Typhlodromus pyri
-
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 4.5 kg ha-1, 28 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for sulcotrione

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 4000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 1.63 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0004 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.0006 A5 Rat, SF=100 -
Dermal penetration studies (%) 0.1-0.5 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public No unacceptable risks to bystanders identified for intended use
Occupational No unacceptable risks to operators or other workers identified for intended use
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B2; C3; D0; E0

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Potential kidney and liver toxicant
May cause eye damage
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
CLP classification 2013 Health: H317, H361d, H373
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Reproduction risk category 3: R63
Xn - Harmful: R43
EC Safety Classification Click here to view information omn the EU safety phrases -
WHO Classification NL - Not listed
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for sulcotrione

Language Name
English sulcotrione
French sulcotrione
German Sulcotrion
Danish sulcotrion
Italian sulcotrione
Spanish sulcotriona
Greek -
Slovenian sulkotrion
Polish sulkotrion
Swedish -
Hungarian -
Dutch sulcotrion

Record last updated: Wednesday 26 June 2019
Contact: aeru@herts.ac.uk