| terbufos (Ref: AC 92100) |
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Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
GENERAL INFORMATION 
for terbufos
Description: An insecticide and nematicide used to control soil and other pests
Example pests controlled: Wireworms; Maggots; Rootworm larvae; White grubs; Black maize beetles; Nematodes; Aphids
Example applications: Corn; Sugarbeet; Sorghum; Sunflower; Citrus; Potatoes; Peanuts
Efficacy & activity: -
Availability status: Current
Introduction & key dates: First registered in US in 1974
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Expired |
| EU Candidate for substitution (CfS) | - |
| Listed in EU database | Yes |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Also used in: Australia, USA
Chemical structure:
| Isomerism | - |
| Chemical formula | C9H21O2PS3 |
| Canonical SMILES | CCOP(=S)(OCC)SCSC(C)(C)C |
| Isomeric SMILES | No data |
| International Chemical Identifier key (InChIKey) | XLNZEKHULJKQBA-UHFFFAOYSA-N |
| International Chemical Identifier (InChI) | InChI=1S/C9H21O2PS3/c1-6-10-12(13,11-7-2)15-8-14-9(3,4)5/h6-8H2,1-5H3 |
| 2D structure diagram/image available? | Yes |
General status:
| Pesticide type | Insecticide, Nematicide | |||
| Substance group | Organophosphate | |||
| Minimum active substance purity | - | |||
| Known relevant impurities | - | |||
| Substance origin | Synthetic | |||
| Mode of action | Systemic. Cholinesterase inhibitor. | |||
| CAS RN | 13071-79-9 | |||
| EC number | 235-963-8 | |||
| CIPAC number | 459 | |||
| US EPA chemical code | 105001 | |||
| PubChem CID | 25670 | |||
| Molecular mass (g mol-1) | 288.4 | |||
| PIN (Preferred Identification Name) | S-[(tert-butylsulfanyl)methyl] O,O-diethyl phosphorodithioate | |||
| IUPAC name | S-tert-butylthiomethyl O,O-diethyl phosphorodithioate | |||
| CAS name | S-[[(1,1-dimethylethyl)thio]methyl] O,O-diethyl phosphorodithioate | |||
| Other status information | Severe Marine Pollutant; Chemical subject to PIC regulations; Found infrequently in drinkwater supplies | |||
| Relevant Environmental Water Quality Standards | - | |||
| Herbicide Resistance Classification (HRAC) | Not applicable | |||
| Herbicide Resistance Classification (WSSA) | Not applicable | |||
| Insecticide Resistance Classification (IRAC) | 1B | |||
| Fungicide Resistance Classification (FRAC) | Not applicable | |||
| Examples of recorded resistance | Diabrotica undecimpunctata Schizaphis graminum |
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| Physical state | Pale yellow liquid | |||
| Related substances & organisms | - | |||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use as a pesticide under EC Regulation 1107/2009 | |||
| Formulation and application details | Usually formulated as granules. | |||
ENVIRONMENTAL FATE
for terbufos
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 4.5 | K4 | Low | |
| Solubility - In organic solvents at 20oC (mg l-1) | 300000 | L2 - Acetone | - | |
| Melting point (oC) | -29.2 | L3 | - | |
| Boiling point (oC) | - | - | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | 88 | L3 - (open cup) | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 3.24 X 1004 | Calculated | - |
| Log P | 4.51 | G4 | High | |
| Bulk density (g ml-1)/Specific gravity | 1.11 | L3 | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 20oC (mPa) | 34.6 | G4 | Highly volatile | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 2.70 | H4 | Moderately volatile | |
GUS leaching potential index  |
1.25 | Calculated | Low leachability | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 2.01 X 10-02 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Low | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
General biodegradability | - |
| Soil degradation (days) (aerobic) | DT50 (typical) | 8 | K4 | Non-persistent |
| DT50 (lab at 20oC) | 5 | H4 | Non-persistent | |
| DT50 (field) | 12 | H4 | Non-persistent | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| DT50 modelling endpoint | - | - | - | |
| Note | Best available data | |||
| Dissipation rate RL50 on plant matrix | Value | - | - | - |
| Note | - | |||
| Dissipation rate RL50 on and in plant matrix | Value | - | - | - |
| Note | - | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | 4.5 | K4 | Moderately fast |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | 6.5 | K4 | Non-persistent |
| Note | Not sensitive to pH | |||
| Water-sediment DT50 (days) | - | - | - | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | G3 | Slightly mobile |
| Koc | 500 | |||
| Notes and range | - | |||
| Freundlich | Kf | 24.4 | R3 | Slightly mobile |
| Kfoc | 700 | |||
| 1/n | 1.09 | |||
| Notes and range | Soil characteristics - New Zealand Tokomaru soil with OC 3.2% | |||
| pH sensitivity | - | |||
Other known metabolites:
| Metabolite name and reference | Aliases | Formation medium / Rate | Estimated maximum occurrence fraction | Metabolising enzymes |
| terbufos sulfoxide | - | Soil; Plant; Animal | - | - |
| terbufos sulfone | - | Soil; Plant; Animal | - | - |
| terbufos oxon sulfoxide | - | a = Soil; b= Plant; c = Animal | a=0.05 | - |
| terbufos oxon sulfone | - | Plant | - | - |
| terbufos oxon | - | Animal | - | - |
| O,O-diethyl phosphorothioate | - | Rats (Urinary) | - | - |
| diethyl phosphate | - | Rats (Urinary) | - | - |
| O,O-diethyl phosphorodithioate | - | Rats (Urinary) | - | - |
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | 286 | F4 | Threshold for concern |
| CT50 (days) | Not available | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 1.3 | G4 Rat | High | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | L2 Rat, 2 year | - |
| (ppm diet) | 1 | - | ||
| Birds - Acute LD50 (mg kg-1) | > 185 | L3 Anas platyrhynchos | Moderate | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | > 0.004 | L3 Lepomis macrochirus | High | |
| Fish - Chronic 21 day NOEC (mg l-1) | 0.0006 | P3 Oncorhynchus mykiss, growth | High | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | 0.00031 | K3 Daphnia magna | High | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | 0.00022 | F3 Americamysis bahia | High | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | 1.4 | K3 Unknown species | Moderate | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | - | - | - | |
| Honeybees (Apis spp.) | Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | 4.1 | F4 | Moderate |
| Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| Bumblebees (Bombus spp.) | Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - |
| - | ||||
| Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| - | ||||
| Mason bees (Osmia spp.) | Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - |
| Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| Other pollinators (1) | Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) | - | - | - |
| Mode of exposure | - | |||
| Other pollinators (2) | Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) | - | - | - |
| Mode of exposure | - | |||
| Earthworms - Acute 14 day LC50 (mg kg-1) | 4 | Q3 | High | |
| Earthworms - Chronic NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms | Acute LC50 (mg kg-1) | - | - | - | Chronic NOEC (mg kg-1) | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for terbufos
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 1.3 | G4 Rat | High | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | 1.0 | L3 Rabbit | - | |
| Mammals - Inhalation LC50 (mg l-1) | 0.0061 | L3 Rat | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | 0.0006 | JMPR 2003 | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | 0.002 | JMPR 2003 | - | |
| AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | List I; List II | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | - | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water Standards | - | - | - | |
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Genotoxic | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
|
A3; B0; C0; D0; E3 | - |
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
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| General human health issues | Highly toxic | |||||||
| Key: Genotoxicity A: Chromosome aberration (EFSA database) B: DNA damage/repair (EFSA database) C: Gene mutation (EFSA database) D: Genome mutation (EFSA database) E: Unspecified genotoxicity type (miscellaneous data source) 0: No data 1: Positive 2: Mixed/ambiguous results 3: Negative |
Key: Other : Yes, known to cause a problem  : No, known not to cause a problem  : Possibly, status not identified - : No data found |
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Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
No information available | |||
| CLP classification 2013 | Health: H300, H310 Environment: H400, H410 |
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| EC Risk Classification |
T+ - Very toxic: R27/28 N - Dangerous for the environment: R50, R53 |
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| EC Safety Classification |
S1/2, S36/37, S45, S60, S61 | |||
| WHO Classification | Ia | - | Extremely hazardous | |
| UN Number | 3018 | |||
| Waste disposal & packaging |
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| Language | Name |
| English | terbufos |
| French | terbuphos |
| German | Terbufos |
| Danish | terbufos |
| Italian | terbufos |
| Spanish | terbufos |
| Greek | terbufos |
| Slovenian | terbufos |
| Polish | terbufos |
| Swedish | - |
| Hungarian | - |
| Dutch | terbufos |
Record last updated: Wednesday 27 November 2019
Contact: aeru@herts.ac.uk