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thiodicarb (Ref: OMS 3026)
** Al3 29311 ** CGA 45156 ** RPA 80600M ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for thiodicarb

Description: A insecticide and molluscicide used to control Lepidoptera, Coleoptera, slugs and other pests fruit, vegetables and many other crops

Example pests controlled: Stem weevils; Black beetles; Springtails; Caterpillars; Cabbage white butterfly; Budworms; Tobacco loopers

Example applications: Cereals including wheat, triticale, rye, barley, oats; Grapes; Forage brassicas; Grass seed crops; Cotton; Maize; Sweetcorn; Pulses; Tomatoes; Tobacco

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1980

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C10H18N4O4S3
Canonical SMILES CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) XDOTVMNBCQVZKG-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3
2D structure diagram/image available? Yes

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Common Name Relationship Link
Thiodicarb - Click here for the CCDC structure diagram

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Molluscicide, Ovicide
Substance group Carbamate
Minimum active substance purity 940 g/kg
Known relevant impurities EU dossier - methomyl 5g/kg
Substance origin Synthetic
Mode of action Mainly stomach action but some contact effects. Cholinesterase inhibitor.
CAS RN 59669-26-0
EC number 261-848-7
CIPAC number 543
US EPA chemical code 114501
PubChem CID 6386307
Molecular mass (g mol-1) 354.47
PIN (Preferred Identification Name) -
IUPAC name (3EZ,12EZ)-3,7,9,13-tetramethyl-5,11-dioxa-2,8,14-trithia-4,7,9,12-tetraazapentadeca-3,12-diene-6,10-dione
CAS name dimethyl N,N'-(thiobis((methylimino)carbonyloxy))bis[ethanimidothioate]
Other status information Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1A
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Helicoverpa armigera
Heliothis virescens
Pseudoplusia includens
Spodoptera exigua
Spodoptera litura
many others
Physical state White powder
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Aventis
  • Bayer CropScience
  • Sipcam
  • Me2
  • Nufarm
Example products using this active
  • Judge
  • Toro
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually sulpplied as read-to-use bait or pellets but may be applied via aerosal dispersal .


ENVIRONMENTAL FATE

for thiodicarb

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 22.2 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 970 A5 - Ethanol -
320 A5 - n-Hexane -
920 A5 - Toluene -
5330 A5 - Acetone -
Melting point (oC) 172.6 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 184.7 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 4.17 X 1001 Calculated -
Log P 1.62 A5 Low
Bulk density (g ml-1)/Specific gravity 1.47 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 2.7 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 4.31 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.56 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 6.42 X 10-05 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Maxima at 232-234nm ~ 18000, >= 290nm = 10 A5 -
Surface tension (mN m-1) 71.97 A5 at 20oC, 94.1% -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 0.67 Click here to see a warning relating to modelling and this active substance A5 Non-persistent
DT50 (lab at 20oC) 0.39 A5 Non-persistent
DT50 (field) 18 B5 Non-persistent
DT90 (lab at 20oC) 2.16 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 0.13-1.2 days, DT90 range 0.42-3.9 days; field studies DT50 range 17.6-18 days, 0.5-45 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 9 A4 Moderately fast
Note Data for Autumn conditions, pH 6, 25 degC USA 35 deg N
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 30.8 A5 Moderately persistent
Note pH sensitive: DT50 69.1 days at pH 5, 0.26 days at pH 9, all at 25 degC
Water-sediment DT50 (days) 0.05 A5 Fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 1.05 A5 Moderately mobile
Kfoc 418
1/n 1.29
Notes and range EU dossier Kfoc range 55.2-1005.7 mL/g
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
methomyl (Ref: OMS 1196) This metabolite may cause environmental pollution, click here for further information Soil   0.800   Major fraction, Relevant
acetic acid Soil   -   Not relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
acetonitrile - Soil (Aerobic); Animal; Water - -
methomyl oxime
Note: DT50 soil = 7 days
- Soil 0.25 -
methomyl methylol - Soil - -
S-methyl-N-[N-methyl-N- (methylaminothio) carbamoyloxy] thioacetamidate - Soil (a = Aerobic, b = Anaerobic) a=0.40 -


ECOTOXICOLOGY

for thiodicarb

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 6.3 A5 Whole fish Low potential
CT50 (days) 12 -
Mammals - Acute oral LD50 (mg kg-1) 50 A5 Rat High
Mammals - Short term dietary NOEL (mg kg-1) 10 B5 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 2023 B5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 5620 mg kg feed-1 A5 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 1.4 A5 Lepomis macrochirus Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.027 A5 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.0016 A5 Daphnia magna High
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.014 F3 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) 0.08 A5 Chironomus riparius Moderate
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 8.3 F4 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) 3.2 Q2 Unknown species Low
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 3.1 A5 Moderate
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 0.153 A5 High
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) 38.5 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 2.0 A5 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 0.4 Mortality
A5 Aphidius rhopalosiphi
-
% Effect 77 Mortality
Dose: 200 kg ha-1
A5 Poecilus cupreus, adult
-
Other arthropod (2) LR50 g ha-1 377 >; Mortality
A4 Typhlodromus pyri
-
% Effect 71 Parasitism
Dose: 200 kg ha-1
A5 Aleochara bilineata, adult
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 10 mg kg-1 soil
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for thiodicarb

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 50 A5 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.66 A5 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.01 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.01 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.03 A3 SF=100 -
Dermal penetration studies (%) 0.15-3.0 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public No unacceptable risks to bystanders identified
Occupational No unacceptable risks to operators or other workers identified
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; Calc MAC=30.0 μg l-1; A5 -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B3; C3; D0; E0

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues USEPA - probable human carcinogen
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H301, H330
Environment: H400
EC Risk Classification Click here to view information omn the EU risk phrases T - Toxic: R23, R25
Xn - Harmful: R43
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S61, S22, S36/37, S45, S60
WHO Classification II - Moderately hazardous
UN Number 2757
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for thiodicarb

Language Name
English thiodicarb
French thiodicarbe
German Thiodicarb
Danish thiodicarb
Italian tiodicarb
Spanish tiodicarb
Greek -
Slovenian tiodikarb
Polish tiodikarb
Swedish tiodikarb
Hungarian -
Dutch -

Record last updated: Saturday 29 June 2019
Contact: aeru@herts.ac.uk