| triazophos (Ref: HOE 002960 ) |
 |
Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
GENERAL INFORMATION 
for triazophos
Description: An insecticide, nematicide and acaricide for the control of a range of insects in a wide range of crops
Example pests controlled: Aphids; Thrips; Midges; Beetles; Sawflies; Apple suckers; Fruit flies; Spidermites; Scale insects
Example applications: Rice; Fruit trees; Vineyards; Sugarcane; Corn; Tobacco; Potatoes; Ornamentals
Efficacy & activity: -
Availability status: Unknown
Introduction & key dates: 1973, first marketed
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Not applicable |
| EU Candidate for substitution (CfS) | Not applicable |
| Listed in EU database | Yes |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Chemical structure:
| Isomerism | None |
| Chemical formula | C12H16N3O3PS |
| Canonical SMILES | CCOP(=S)(OCC)OC1=NN(C=N1)C2=CC=CC=C2 |
| Isomeric SMILES | No data |
| International Chemical Identifier key (InChIKey) | AMFGTOFWMRQMEM-UHFFFAOYSA-N |
| International Chemical Identifier (InChI) | InChI=1S/C12H16N3O3PS/c1-3-16-19(20,17-4-2)18-12-13-10-15(14-12)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3 |
| 2D structure diagram/image available? | Yes |
General status:
| Pesticide type | Insecticide, Acaricide, Nematicide | |
| Substance group | Organophosphate | |
| Minimum active substance purity | - | |
| Known relevant impurities | - | |
| Substance origin | Synthetic | |
| Mode of action | Non-systemic, broad spectrum with contact and stomach action. Cholinesterase inhibitor. | |
| CAS RN | 24017-47-8 | |
| EC number | 245-986-5 | |
| CIPAC number | 353 | |
| US EPA chemical code | 344600 | |
| PubChem CID | 32184 | |
| Molecular mass (g mol-1) | 313.3 | |
| PIN (Preferred Identification Name) | O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate | |
| IUPAC name | O,O-diethyl O-1-phenyl-1H-1,2,4-triazol-3-yl phosphorothioate | |
| CAS name | O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate | |
| Other status information | Marine Pollutant; Chemical subject to PIC regulations | |
| Relevant Environmental Water Quality Standards | UK statutory standard for the protection of aquatic life: annual mean conc for inland, coastal and territorial waters; 0.005 ug/L | |
| Herbicide Resistance Classification (HRAC) | Not applicable | |
| Herbicide Resistance Classification (WSSA) | Not applicable | |
| Insecticide Resistance Classification (IRAC) | 1B | |
| Fungicide Resistance Classification (FRAC) | Not applicable | |
| Examples of recorded resistance | Bemisia tabaci Chilo suppressalis Epiphyas postvittana Plutella xylostella Spodoptera littoralis Spodoptera litura |
|
| Physical state | Yellow-brown oily liquid | |
| Related substances & organisms | ||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
|
|||
| Example products using this active |
|
|||
| UK LERAP status | No UK approval for use as a pesticide under EC Regulation 1107/2009 | |||
| Formulation and application details | Usually supplied as an emulsifiable concentrate, wettable powder, granules or ULV. | |||
ENVIRONMENTAL FATE
for triazophos
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 35 | B5 | Low | |
| Solubility - In organic solvents at 20oC (mg l-1) | 11100 | L3 - n-Hexane | - | |
| 50000 | L3 - Acetone | - | ||
| 500000 | L3 - Methanol | - | ||
| 500000 | L3 - Ethyl acetate | - | ||
| Melting point (oC) | 2.5 | L3 | - | |
| Boiling point (oC) | Decomposes before boiling | L3 | - | |
| Degradation point (oC) | 140 | L3 | - | |
| Flashpoint (oC) | - | - | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 3.55 X 1003 | Calculated | - |
| Log P | 3.55 | B5 | High | |
| Bulk density (g ml-1)/Specific gravity | 1.24 | B5 | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 20oC (mPa) | 1.33 | B4 | Low volatility | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 4.90 X 10-03 | V3 | Non-volatile | |
GUS leaching potential index  |
2.38 | Calculated | Transition state | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 1.73 X 10-02 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Medium | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
General biodegradability | - |
| Soil degradation (days) (aerobic) | DT50 (typical) | 44 | B5 | Moderately persistent |
| DT50 (lab at 20oC) | 44 | B5 | Moderately persistent | |
| DT50 (field) | 9 | L3 | Non-persistent | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| DT50 modelling endpoint | - | - | - | |
| Note | Lab studies DT50 range 20-50 days, field studies DT50 range 7-46 days | |||
| Dissipation rate RL50 on plant matrix | Value | 2.2 | R3 | - |
| Note | Pepper fruit, n=1 | |||
| Dissipation rate RL50 on and in plant matrix | Value | 7.1 | R4 | - |
| Note | Published literature RL50 range 1.0-11.4 days, 10 field grown crops, various matrices, n=12 | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | 21 | V2 | Slow |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | 140 | K4 | Persistent |
| Note | - | |||
| Water-sediment DT50 (days) | 35 | K3 | Moderately fast | |
| Water phase only DT50 (days) | 35 | K3 | Stable | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | B5 | Moderately mobile |
| Koc | 358 | |||
| Notes and range | - | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
Other known metabolites:
| Metabolite name and reference | Aliases | Formation medium / Rate | Estimated maximum occurrence fraction | Metabolising enzymes |
| 1-phenyl-3-hydroxy-1,2,4-triazole | - | a = Soil; b = Animal (Faecal) | a=0.005 | - |
| triazophos oxon | - | Soil | - | - |
| urea | - | Soil | - | - |
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | 300 | Q2 Estimated | Threshold for concern |
| CT50 (days) | Not available | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 66 | B5 Rat | High | |
| Mammals - Short term dietary NOEL | (mg kg-1) | 1.5 | B5 Rat | High |
| (ppm diet) | 20 | - | ||
| Birds - Acute LD50 (mg kg-1) | 8.3 | B5 Colinus virginianus | High | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | 0.038 | B5 Oncorhynchus mykiss | High | |
| Fish - Chronic 21 day NOEC (mg l-1) | 0.0005 | Q2 Oncorhynchus mykiss | High | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | 0.0026 | B5 Daphnia magna | High | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | 0.01 | Q2 Daphnia magna | Moderate | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | 9.1 | B5 Scenedemus subspicatus | Moderate | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | 0.1 | Q2 Unknown species | Moderate | |
| Honeybees (Apis spp.) | Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | 59.8 | R4 | Moderate |
| Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| Bumblebees (Bombus spp.) | Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - |
| - | ||||
| Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| - | ||||
| Mason bees (Osmia spp.) | Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - |
| Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) | - | - | - | |
| Other pollinators (1) | Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) | - | - | - |
| Mode of exposure | - | |||
| Other pollinators (2) | Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) | - | - | - |
| Mode of exposure | - | |||
| Earthworms - Acute 14 day LC50 (mg kg-1) | 466 | B5 Eisenia foetida | Moderate | |
| Earthworms - Chronic NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms | Acute LC50 (mg kg-1) | - | - | - | Chronic NOEC (mg kg-1) | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | Harmful | AA2 Typhlodromus pyri | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | Harmful | AA2 Chrysoperla carnea | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for triazophos
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 66 | B5 Rat | High | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | > 2000 | L3 Rat | - | |
| Mammals - Inhalation LC50 (mg l-1) | 0.53 | L3 Rat | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | 0.001 | JMPR 1993 | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | 0.001 | JMPR 2003 | - | |
| AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | 0.05 | UK ACP 1999 | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | List I; List II | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | - | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water Standards | - | - | - | |
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Genotoxic | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
|
A3; B0; C0; D0; E0 | - |
- |
|
|
|||
| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
|
|
- |
|
- |
|
|||
| General human health issues | Acts as a toxicant to most major organs | |||||||
| Key: Genotoxicity A: Chromosome aberration (EFSA database) B: DNA damage/repair (EFSA database) C: Gene mutation (EFSA database) D: Genome mutation (EFSA database) E: Unspecified genotoxicity type (miscellaneous data source) 0: No data 1: Positive 2: Mixed/ambiguous results 3: Negative |
Key: Other : Yes, known to cause a problem  : No, known not to cause a problem  : Possibly, status not identified - : No data found |
|||||||
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
No information available | |||
| CLP classification 2013 | Health: H301, H312, H331 Environment: H400, H410 |
|||
| EC Risk Classification |
T - Toxic: R23/25 Xn - Harmful: R21 N - Dangerous for the environment: R50, R53 |
|||
| EC Safety Classification |
S1/2, S36/37, S45, S61 | |||
| WHO Classification | Ib | - | Highly hazardous | |
| UN Number | 3018 | |||
| Waste disposal & packaging |
- | |||
| Language | Name |
| English | triazophos |
| French | triazophos |
| German | Triazophos |
| Danish | triazophos |
| Italian | triazofos |
| Spanish | triazofos |
| Greek | - |
| Slovenian | triazofos |
| Polish | triazofos |
| Swedish | - |
| Hungarian | - |
| Dutch | triazofos |
Record last updated: Wednesday 30 May 2018
Contact: aeru@herts.ac.uk