Uniconazole (Ref: XE 1019)
Last updated: 21/01/2023
(Also known as: S-uniconazole; lomica; S 3307D)
Uniconazole is a plant growth regulator. It has a low water solubility, is quite volatile and there is also a slight risk of leaching to groundwater. It can be persistent in both soil and aquatic systems. It is moderately toxic to mammals but would not be expected to bioaccumulate. It shows a moderate level of toxicity to most aquatic species honey bees, earthworms and birds.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A plant growth regulator used to reduce vegetative growth and increase flowering
Growth
Bedding plants including calibrachoa, celosia, petunia, salvia, scaevola, dahlia, marigold, verbena, viola; Woody landscape ornamentals; Tomatoes; Peppers; Cucumbers; Avocado
-
Current
1985
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
Exists as optical isomers. Uniconazole-P is the most biologically active isomer.
C₁₅H₁₈ClN₃O
CC(C)(C)C(C(=CC1=CC=C(C=C1)Cl)N2C=NC=N2)O
CC(C)(C)C(/C(=C\C1=CC=C(C=C1)Cl)/N2C=NC=N2)O
YNWVFADWVLCOPU-MDWZMJQESA-N
InChI=1S/C15H18ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-10,14,20H,1-3H3/b13-8+/t14-/m1/s1
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
(R)-(-)-uniconazole
Isomer
Plant Growth Regulator
Triazole fungicide; Conazole fungicide
-
-
Synthetic
Inhibits gibberellin biosynthesis
83657-22-1
617-483-4
None allocated
128976
6436604
No data found
291.78
rac-(1E,3R)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol
(E)-(RS)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol
(βE)-β-((4-chlorophenyl)methylene)-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol
-
-
Not applicable
Not applicable
Not applicable
Not known
-
Off-white crystalline solid
Uniconazole 50 Sumagic Plant Growth Regulator Sunny
Usually supplied as a suspension concentrate for use as a foliar spray, drench or bulb dip
8.41
at 25 °C
Low
88000
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Methanol mg kg⁻¹
-
300
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Hexane mg kg⁻¹
-
7000
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Xylene mg kg⁻¹
-
155.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
475
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
-
-
-
-
-
6.92 X 1003
Calculated
-
3.84
K3 K = Research datasets, e.g. Pandora, Demetra 3 = Unverified data of known source
High
Likely to be soluble
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
Based on chemical group
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
1.18
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
13.07
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
-
-
8.9
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately volatile
-
-
-
-
-
-
-
-
-
-
100
Persistent
100
Persistent
435
Very persistent
-
-
-
-
-
-
-
-
-
Best available data
-
-
-
-
4.1
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
-
Wheat, whole plant, n=1
30
Stable
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Slightly mobile
670
Koc range 250 (sandy loam) to 1100 (loam) mL g⁻¹, Soils=11
-
-
-
-
-
-
-
3.10
Calculated
High leachability
3.89 X 10-01
Calculated
-
-
Medium
Calculated
-
Slightly mobile
Calculated
-
-
-
-
-
-
Known groundwater metabolites
None
None
Terrestrial ecotoxicology
430
Rat
Moderate
2.25
Rat
High
-
-
-
-
-
> 1155
Colinus virginianus
Moderate
-
-
-
-
-
-
1000
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 20
Apis mellifera
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
14.8
Oncorhynchus mykiss
Moderate
-
-
-
10
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
430
Rat
Moderate
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
2.75
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat 4 hr
-
-
-
-
0.02
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
EU MRL pesticide database 
-
-
-
-
-
-
-
-
-
-
Carcinogen
Endocrine disruptor
?Possibly, status not identified
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
?Possibly, status not identified
No data found
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
Slightly toxic if ingested USEPA - possible human carcinogen
No information available
Health: H302
II (Moderately hazardous)
Not regulated
-
uniconazole
uniconazole
Uniconazol
uniconazol
uniconazolo
uniconazol
-
unikonazol
-
-
-
Record last updated:
21/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242