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GET ADDITIONAL DATA HERE!

vamidothion (Ref: ENT 26613)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for vamidothion

Description: An insecticide and acaricide which provides persistent control of piercing and sucking pests

Example pests controlled: Aphids including wooly apple aphids, citrus aphid, cotton aphid; Spidermites; Thrips

Example applications: Cotton; Apples; Citrus; Rice; Beans; Maize; Sorghum

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1962, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Portugal
Date inclusion expires Expired
EU Candidate for substitution (CfS) Not applicable
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism Chiral, a specific isomer or a derivative of a chiral molecule
Chemical formula C8H18NO4PS2
Canonical SMILES CC(C(=O)NC)SCCSP(=O)(OC)OC
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) LESVOLZBIFDZGS-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C8H18NO4PS2/c1-7(8(10)9-2)15-5-6-16-14(11,12-3)13-4/h7H,5-6H2,1-4H3,(H,9,10)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide
Substance group Organophosphate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Systemic. Cholinesterase inhibitor.
CAS RN 2275-23-2
EC number 218-894-8
CIPAC number 117
US EPA chemical code 379200
PubChem CID 560193
Molecular mass (g mol-1) 287.34
PIN (Preferred Identification Name) rac-O,O-dimethyl S-(2-{[(2R)-1-(methylamino)-1-oxopropan-2-yl]sulfanyl}ethyl) phosphorothioate
IUPAC name O,O-dimethyl S-(RS)-2-(1-methylcarbamoylethylthio)ethyl phosphorothioate
CAS name O,O-dimethyl S-[2-[[1-methyl-2-(methylamino)-2-oxoethyl]thio]ethyl] phosphorothioate
Other status information Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state White crystalline needles
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Rhone poulenc
Example products using this active
  • Asystin Z
  • Kilval
  • Trucidor
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplued as an emulsifiable concentrate.


ENVIRONMENTAL FATE

for vamidothion

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 4000 K4 High
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting point (oC) 43 L3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 6.17 X 10-05 Calculated -
Log P -4.21 L3 Low
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 1.00 X 10-10 L2 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 8.71 X 10-11 V3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.55 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.29 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 1.8 K4 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) 0.2 L3 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Best available data
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 119 K3 Persistent
Note -
Water-sediment DT50 (days) 7 K3 Fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - W3 Mobile
Koc 70
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
vamidothion sulfoxide - Soil; Rat - -
vamidothion sulfone - Intermediary product - -
vamidothion sulfoxide sulfonic acid - Soil - -
des-O-methyl vamidothion - Plant - -
dimethyl phosphate - Plant; Animal; Rat (Urinary) - -
monomethylphosphate - Animal; Rat (Urinary) - -
O,O-dimethyl phosphorothioate - Animal - -


ECOTOXICOLOGY

for vamidothion

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 75 Q2 Estimated Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 64 L3 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - L3 Rat -
(ppm diet) 50 -
Birds - Acute LD50 (mg kg-1) > 35 L2 Phasianidae High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) > 590 L2 Danio rerio Low
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 0.19 L3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) > 1525 K3 Unknown species Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 0.56 R4 High
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Harmful Dose: 300 g ha-1
AA3 Typhlodromus pyri
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect Harmful Dose: 300 g ha-1
AA3 Chrysoperla carnea
-
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for vamidothion

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 64 L3 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) > 1160 L3 Rabbit -
Mammals - Inhalation LC50 (mg l-1) 1.73 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.008 A5 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

-

-

General human health issues May cause abdominal cramps, vomiting and diarrhoa if ingested

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes IMDG Transport Code is 6.1
Will emit toxic and irritating fumes in a fire
CLP classification 2013 Health: H301, H312
Environment: H400
EC Risk Classification Click here to view information omn the EU risk phrases T - Toxic: R25
Xn - Harmful: R21
N - Dangerous for the environment: R50
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S36/37, S45, S61
WHO Classification Ib - Highly hazardous
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Active 2783, liquid products usually 3018
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for vamidothion

Language Name
English vamidothion
French vamidothion
German Vamidothion
Danish vamidothion
Italian vamidotion
Spanish vamidotion
Greek -
Slovenian vamidotion
Polish wamidotion
Swedish -
Hungarian -
Dutch vamidothion

Record last updated: Wednesday 30 May 2018
Contact: aeru@herts.ac.uk